Project name: d3935451bbaf969

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGSFTFSSYNMGWFRQAPGKGRELVAAIGSDGSTSSKDSRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAGYGGSSNEGAWDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:42)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:43)

• Minimal score value: -2.7148
• Maximal score value: 1.0238
• Average score: -0.8412
• Total score value: -100.1074

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.0874
2	V	A	-1.1674
3	Q	A	-0.9950
4	L	A	0.0000
5	V	A	0.6486
6	E	A	-0.1880
7	S	A	-0.7711
8	G	A	-1.1966
9	G	A	-0.8240
10	G	A	-0.0467
11	L	A	1.0238
12	V	A	-0.0315
13	Q	A	-1.3425
14	P	A	-1.6849
15	G	A	-1.5674
16	G	A	-1.1022
17	S	A	-1.5705
18	L	A	-1.1516
19	R	A	-2.3748
20	L	A	0.0000
21	S	A	-0.5031
22	C	A	0.0000
23	A	A	-0.1800
24	A	A	0.0000
25	S	A	-0.9801
26	G	A	-1.3028
27	S	A	-0.9384
28	F	A	0.0000
29	T	A	-0.4151
30	F	A	0.0000
31	S	A	-1.0062
32	S	A	-0.5019
33	Y	A	0.0000
34	N	A	-0.4463
35	M	A	0.0000
36	G	A	0.0000
37	W	A	0.0000
38	F	A	0.0000
39	R	A	0.0000
40	Q	A	-1.5360
41	A	A	-1.6461
42	P	A	-1.3728
43	G	A	-1.6489
44	K	A	-2.5977
45	G	A	-2.0629
46	R	A	-2.1954
47	E	A	-2.0121
48	L	A	-1.1312
49	V	A	0.0000
50	A	A	0.0000
51	A	A	0.0000
52	I	A	0.0000
53	G	A	-1.0492
54	S	A	-1.2878
55	D	A	-2.1619
56	G	A	-1.6090
57	S	A	-1.0556
58	T	A	-0.7391
59	S	A	-0.7741
60	S	A	-1.1098
61	K	A	-1.7929
62	D	A	-1.2822
63	S	A	-1.0233
64	R	A	-1.2696
65	F	A	0.0000
66	T	A	-1.0752
67	I	A	0.0000
68	S	A	-0.5319
69	R	A	-1.0398
70	D	A	-1.5473
71	N	A	-1.8434
72	A	A	-1.4462
73	K	A	-2.2778
74	R	A	-1.7204
75	M	A	-0.9070
76	V	A	0.0000
77	Y	A	-0.6355
78	L	A	0.0000
79	Q	A	-1.7826
80	M	A	0.0000
81	N	A	-2.1867
82	S	A	-1.5475
83	L	A	0.0000
84	R	A	-2.5165
85	A	A	-1.8063
86	E	A	-2.2961
87	D	A	0.0000
88	T	A	-0.8957
89	A	A	0.0000
90	V	A	-0.4689
91	Y	A	0.0000
92	Y	A	-0.2727
93	C	A	0.0000
94	A	A	0.0000
95	A	A	0.0000
96	G	A	0.0000
97	Y	A	0.6124
98	G	A	-0.3479
99	G	A	-0.5574
100	S	A	-0.9774
101	S	A	-1.5707
102	N	A	-2.4561
103	E	A	-2.7148
104	G	A	-1.8863
105	A	A	-1.3682
106	W	A	0.0000
107	D	A	-1.6536
108	Y	A	-0.4990
109	W	A	-0.3349
110	G	A	-0.1870
111	Q	A	-0.9775
112	G	A	-0.6682
113	T	A	-0.8115
114	Q	A	-1.0284
115	V	A	0.0000
116	T	A	-0.3282
117	V	A	0.0000
118	S	A	-0.8087
119	S	A	-0.6858