Project name: d66d64b1361c3b4

Chain sequence(s)	H: QVQLVESGGGLVQAGDSLRLSCGASGGTFSRYGMGWFRQAPGKEREFVASITWSSGSTYYADSVKGRFTMSMDTAKTTVYLQMNSLKPEDTAAYYCAAELFGLGSANPHEYNAWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:08)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:08)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:08)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:08)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:08)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:32)

• Minimal score value: -2.8888
• Maximal score value: 2.398
• Average score: -0.5068
• Total score value: -62.8371

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.4666
2	V	H	-1.0570
3	Q	H	-1.0400
4	L	H	0.0000
5	V	H	1.0385
6	E	H	0.3362
7	S	H	-0.2761
8	G	H	-0.5844
9	G	H	0.1559
11	G	H	0.8377
12	L	H	1.4070
13	V	H	0.0000
14	Q	H	-1.8473
15	A	H	-2.1582
16	G	H	-2.0943
17	D	H	-2.6013
18	S	H	-1.7469
19	L	H	-0.8055
20	R	H	-1.2991
21	L	H	0.0000
22	S	H	-0.2319
23	C	H	0.0000
24	G	H	-0.1778
25	A	H	0.0000
26	S	H	-0.8658
27	G	H	-1.1156
28	G	H	-1.0823
29	T	H	-1.1374
30	F	H	0.0000
35	S	H	-1.1337
36	R	H	-1.2482
37	Y	H	0.3742
38	G	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.4295
45	A	H	-1.4191
46	P	H	-1.1553
47	G	H	-1.6204
48	K	H	-2.5650
49	E	H	-2.8888
50	R	H	-1.9274
51	E	H	-1.2935
52	F	H	-0.3988
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	I	H	0.0000
57	T	H	0.0067
58	W	H	-0.6164
59	S	H	-0.8976
62	S	H	-0.5887
63	G	H	-0.6275
64	S	H	-0.2852
65	T	H	0.3076
66	Y	H	0.8212
67	Y	H	-0.1583
68	A	H	-0.9093
69	D	H	-2.1469
70	S	H	-1.5779
71	V	H	0.0000
72	K	H	-1.8232
74	G	H	-1.4654
75	R	H	-1.3450
76	F	H	0.0000
77	T	H	-0.5094
78	M	H	0.0000
79	S	H	-0.1045
80	M	H	-0.2274
81	D	H	-0.6882
82	T	H	-0.5995
83	A	H	-0.8476
84	K	H	-1.7872
85	T	H	-1.0615
86	T	H	-0.4991
87	V	H	0.0000
88	Y	H	-0.2684
89	L	H	0.0000
90	Q	H	-0.7873
91	M	H	0.0000
92	N	H	-1.6116
93	S	H	-1.6747
94	L	H	0.0000
95	K	H	-2.6903
96	P	H	-1.9532
97	E	H	-2.3645
98	D	H	0.0000
99	T	H	-0.5779
100	A	H	0.0000
101	A	H	0.2682
102	Y	H	0.0000
103	Y	H	0.2223
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	E	H	0.0000
108	L	H	1.7952
109	F	H	2.3980
110	G	H	1.0239
111	L	H	1.8464
111A	G	H	1.0529
111B	S	H	0.2756
112B	A	H	-0.0868
112A	N	H	-1.0378
112	P	H	-1.1782
113	H	H	-1.7367
114	E	H	-0.7713
115	Y	H	0.0000
116	N	H	-1.3093
117	A	H	-0.7655
118	W	H	-0.1935
119	G	H	-0.2995
120	Q	H	-0.6161
121	G	H	-0.0305
122	T	H	0.4038
123	L	H	1.4022
124	V	H	0.0000
125	T	H	0.2225
126	V	H	0.0000
127	S	H	-0.7950
128	S	H	-0.8520