Project name: dc5ac21145d354c

Chain sequence(s)	H: EVQLVESGGGVVQPGGSLRLSCAASGFTFRSFGMSWVRQAPGKGPEWVSSISGSGSDTLYADSVKGRFTISRDNSKNTLYLQMNSLRPEDTALYYCTIGGSLSRSSQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:58)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:00)

• Minimal score value: -2.3957
• Maximal score value: 1.618
• Average score: -0.5341
• Total score value: -61.4229

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.6755
2	V	H	-0.6466
3	Q	H	-0.9503
4	L	H	0.0000
5	V	H	1.2239
6	E	H	0.0000
7	S	H	0.0657
8	G	H	-0.6189
9	G	H	0.1230
11	G	H	0.7473
12	V	H	1.6180
13	V	H	0.1476
14	Q	H	-1.2822
15	P	H	-1.4373
16	G	H	-1.3954
17	G	H	-0.8768
18	S	H	-0.9602
19	L	H	-0.4083
20	R	H	-1.2047
21	L	H	0.0000
22	S	H	-0.1073
23	C	H	0.0000
24	A	H	-0.0435
25	A	H	0.0000
26	S	H	-0.7950
27	G	H	-1.0251
28	F	H	-0.4722
29	T	H	-0.4510
30	F	H	0.0000
35	R	H	-2.0385
36	S	H	-0.7634
37	F	H	0.0973
38	G	H	-0.5087
39	M	H	0.0000
40	S	H	0.3134
41	W	H	0.0000
42	V	H	0.3848
43	R	H	0.0000
44	Q	H	-0.6397
45	A	H	0.0000
46	P	H	-0.8402
47	G	H	-1.1181
48	K	H	-1.4564
49	G	H	-1.2250
50	P	H	-0.7866
51	E	H	-0.4775
52	W	H	0.3721
53	V	H	0.0000
54	S	H	0.0000
55	S	H	0.1228
56	I	H	0.0000
57	S	H	-0.8681
58	G	H	-1.0529
59	S	H	-1.1342
62	G	H	-1.3045
63	S	H	-1.1103
64	D	H	-1.4423
65	T	H	-0.3045
66	L	H	0.4338
67	Y	H	-0.2836
68	A	H	-0.9584
69	D	H	-2.3111
70	S	H	-1.5961
71	V	H	0.0000
72	K	H	-2.3957
74	G	H	-1.6960
75	R	H	-1.5225
76	F	H	0.0000
77	T	H	-0.5465
78	I	H	0.0000
79	S	H	-0.3262
80	R	H	-1.1151
81	D	H	-1.6348
82	N	H	-2.0229
83	S	H	-1.7242
84	K	H	-2.2716
85	N	H	-1.9751
86	T	H	-1.0393
87	L	H	0.0000
88	Y	H	-0.2449
89	L	H	0.0000
90	Q	H	-0.7652
91	M	H	0.0000
92	N	H	-1.1810
93	S	H	-1.1895
94	L	H	0.0000
95	R	H	-1.9582
96	P	H	-1.4543
97	E	H	-1.2992
98	D	H	0.0000
99	T	H	-0.1912
100	A	H	0.0000
101	L	H	0.5112
102	Y	H	0.0000
103	Y	H	0.4120
104	C	H	0.0000
105	T	H	0.0000
106	I	H	-0.2250
107	G	H	-0.4740
108	G	H	-0.4550
114	S	H	-0.0025
115	L	H	0.7637
116	S	H	-0.4706
117	R	H	-1.6557
118	S	H	-1.2902
119	S	H	-0.7871
120	Q	H	-1.0228
121	G	H	0.0409
122	T	H	0.4325
123	L	H	1.2061
124	V	H	0.0000
125	T	H	0.3892
126	V	H	0.0000
127	S	H	-0.7222
128	S	H	-0.5993