Project name: debfef0cc1726a0

Chain sequence(s)	G: IQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSSYSLITFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
Selected Chain(s)	G
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with G chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:09)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:10)

• Minimal score value: -3.5386
• Maximal score value: 3.104
• Average score: -0.625
• Total score value: -131.873

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	I	G	-0.1549
3	Q	G	-1.6017
4	M	G	0.0000
5	T	G	-1.2296
6	Q	G	0.0000
7	S	G	-0.8099
8	P	G	-0.6700
9	S	G	-0.9186
10	S	G	-0.8237
11	L	G	-0.5491
12	S	G	-0.9731
13	A	G	-1.0735
14	S	G	-1.0402
15	V	G	-0.4400
16	G	G	-0.8357
17	D	G	-1.8521
18	R	G	-2.3657
19	V	G	0.0000
20	T	G	-0.6215
21	I	G	0.0000
22	T	G	-0.9073
23	C	G	0.0000
24	R	G	-2.6360
25	A	G	0.0000
26	S	G	-1.6248
27	Q	G	-1.3401
28	S	G	-0.2131
29	V	G	1.3585
36	S	G	0.6495
37	S	G	-0.0529
38	A	G	0.2864
39	V	G	0.0000
40	A	G	0.0000
41	W	G	0.0000
42	Y	G	-0.1415
43	Q	G	0.0000
44	Q	G	-1.7266
45	K	G	-2.3482
46	P	G	-1.6711
47	G	G	-1.8032
48	K	G	-2.5060
49	A	G	-1.5578
50	P	G	-1.4917
51	K	G	-1.5718
52	L	G	0.1864
53	L	G	0.0000
54	I	G	0.0000
55	Y	G	1.5839
56	S	G	0.3294
57	A	G	0.0000
65	S	G	-0.1163
66	S	G	0.7366
67	L	G	1.4669
68	Y	G	1.6576
69	S	G	0.4749
70	G	G	-0.0014
71	V	G	0.2278
72	P	G	-0.0761
74	S	G	-0.3572
75	R	G	-0.8472
76	F	G	0.0000
77	S	G	-0.2870
78	G	G	-0.4436
79	S	G	-1.3784
80	R	G	-2.5693
83	S	G	-1.7288
84	G	G	-1.2230
85	T	G	-1.4302
86	D	G	-1.8955
87	F	G	0.0000
88	T	G	-1.0833
89	L	G	0.0000
90	T	G	-0.6206
91	I	G	0.0000
92	S	G	-1.3518
93	S	G	-1.1834
94	L	G	0.0000
95	Q	G	-1.4177
96	P	G	-1.9549
97	E	G	-2.4819
98	D	G	0.0000
99	F	G	0.0000
100	A	G	0.0000
101	T	G	-0.9770
102	Y	G	0.0000
103	Y	G	-0.0310
104	C	G	0.0000
105	Q	G	0.0000
106	Q	G	0.0000
107	S	G	1.5819
108	S	G	1.7384
109	Y	G	1.9572
114	S	G	1.5906
115	L	G	2.8267
116	I	G	3.1040
117	T	G	1.5953
118	F	G	1.4888
119	G	G	0.0000
120	Q	G	-1.2020
121	G	G	0.0000
122	T	G	0.0000
123	K	G	-1.7022
124	V	G	0.0000
125	E	G	-1.1400
126	I	G	0.0000
127	K	G	-1.5298
128	R	G	-0.9406
129	T	G	0.0755
130	V	G	1.2453
131	A	G	0.6249
132	A	G	0.1940
133	P	G	-0.1940
134	S	G	-0.0731
135	V	G	0.0000
136	F	G	1.6435
137	I	G	1.4240
138	F	G	1.5097
139	P	G	0.1361
140	P	G	0.0000
141	S	G	-1.7508
142	D	G	-3.1958
143	E	G	-3.4348
144	Q	G	-2.4181
145	L	G	-2.4838
146	K	G	-2.9624
147	S	G	-1.8830
148	G	G	-1.3191
149	T	G	-0.9808
150	A	G	0.0000
151	S	G	0.0582
152	V	G	0.0000
153	V	G	0.6426
154	C	G	0.0000
155	L	G	0.7773
156	L	G	0.0000
157	N	G	-0.4388
158	N	G	-1.2049
159	F	G	0.0000
160	Y	G	-0.6484
161	P	G	-1.1486
162	R	G	-2.1155
163	E	G	-2.7360
164	A	G	-2.0818
165	K	G	-2.1260
166	V	G	-1.0045
167	S	G	-0.1576
168	W	G	0.0000
169	Y	G	0.1726
170	V	G	0.0000
171	D	G	-1.6343
172	N	G	-1.2539
173	A	G	-0.0386
174	L	G	1.0366
175	Q	G	-0.0446
176	S	G	-0.5795
177	G	G	-1.4303
178	N	G	-1.8335
179	S	G	-1.7756
180	Q	G	-2.3931
181	E	G	-1.9918
182	S	G	-0.9609
183	V	G	-0.3192
184	T	G	-0.8910
185	E	G	-2.1355
186	Q	G	0.0000
187	D	G	-2.4159
188	S	G	-2.4974
189	K	G	-2.5396
190	D	G	-1.8058
191	S	G	0.0000
192	T	G	0.0000
193	Y	G	0.0000
194	S	G	-0.7194
195	L	G	-0.5500
196	S	G	-0.1898
197	S	G	0.0000
198	T	G	-0.8147
199	L	G	0.0000
200	T	G	-0.7093
201	L	G	-0.7236
202	S	G	-0.8952
203	K	G	-1.9166
204	A	G	-1.7688
205	D	G	-2.3336
206	Y	G	0.0000
207	E	G	-3.4257
208	K	G	-3.5386
209	H	G	-2.7436
210	K	G	-2.7633
211	V	G	-0.9317
212	Y	G	0.0000
213	A	G	0.0000
214	C	G	0.0000
215	E	G	-0.6490
216	V	G	0.0000
217	T	G	-1.1232
218	Q	G	-1.3390
219	G	G	-1.1072
220	T	G	-0.4550
221	T	G	-0.2933
222	S	G	-0.4017
223	V	G	0.1470
224	T	G	-0.1301
225	K	G	-0.2541
226	S	G	-0.0579
227	F	G	-0.4868
228	N	G	-1.5138
229	R	G	-2.0973
230	G	G	-1.6510
231	E	G	-2.0309
232	C	G	-0.3670