Project name: dfcd0747d72524b

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASAYYVKWFRQAPGKGRELVASPASPGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAASPDSSGTVYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:08)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:08)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:08)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:08)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:08)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:03)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:03)

• Minimal score value: -3.1253
• Maximal score value: 1.6534
• Average score: -0.7783
• Total score value: -79.3827

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-1.9293
2	V	A	-0.8230
3	Q	A	-1.2536
4	L	A	0.0000
5	V	A	-0.0091
6	E	A	0.0000
7	S	A	-0.8113
8	G	A	-0.9607
9	G	A	-0.7883
10	G	A	-0.0639
11	L	A	0.9998
12	V	A	-0.0777
13	Q	A	-1.3525
14	P	A	-1.7007
15	G	A	-1.5241
16	G	A	-1.1812
17	S	A	-1.4306
18	L	A	-1.0347
19	R	A	-2.1113
20	L	A	0.0000
21	S	A	-0.5211
22	C	A	0.0000
23	A	A	-0.8754
24	A	A	0.0000
25	S	A	-0.8909
26	A	A	0.0000
27	Y	A	1.3743
28	Y	A	1.6534
29	V	A	0.0000
30	K	A	-0.0304
31	W	A	0.0000
32	F	A	-0.1114
33	R	A	-1.0944
34	Q	A	-2.0309
35	A	A	-1.9027
36	P	A	-1.3362
37	G	A	-1.7785
38	K	A	-2.9419
39	G	A	-2.5981
40	R	A	-2.7320
41	E	A	-1.7997
42	L	A	0.1891
43	V	A	-0.0120
44	A	A	0.0000
45	S	A	0.0000
46	P	A	-0.2698
47	A	A	-0.2891
48	S	A	-0.3978
49	P	A	-0.7642
50	G	A	-1.1818
51	R	A	-1.5392
52	F	A	0.0000
53	T	A	-0.8677
54	I	A	-0.4908
55	S	A	-0.5806
56	R	A	-1.1765
57	D	A	-2.2367
58	N	A	-2.5889
59	A	A	-2.1114
60	K	A	-3.1253
61	R	A	-3.0487
62	M	A	-1.6590
63	V	A	0.0000
64	Y	A	-0.5834
65	L	A	0.0000
66	Q	A	-1.4342
67	M	A	0.0000
68	N	A	-1.7752
69	S	A	-1.4783
70	L	A	0.0000
71	R	A	-2.7550
72	A	A	-1.9506
73	E	A	-2.3893
74	D	A	0.0000
75	T	A	-0.9906
76	A	A	0.0000
77	V	A	-0.6179
78	Y	A	0.0000
79	Y	A	-0.2970
80	C	A	0.0000
81	A	A	0.0000
82	A	A	0.0000
83	S	A	-0.0065
84	P	A	-0.4514
85	D	A	-2.0757
86	S	A	-1.4123
87	S	A	-1.0335
88	G	A	-0.8394
89	T	A	-0.1778
90	V	A	0.9167
91	Y	A	0.7506
92	W	A	0.5127
93	G	A	-0.2950
94	Q	A	-0.9402
95	G	A	-0.6861
96	T	A	-0.8580
97	Q	A	-1.0506
98	V	A	0.0000
99	T	A	-0.3531
100	V	A	0.0000
101	S	A	-0.7920
102	S	A	-0.5011