Project name: dfe123355a1fb8

Chain sequence(s)	H: QVQLQESGGGLVQPGGSLRLSCVLSNGIFSTYGMNWYRQAPGKQREFVASITSSGSTNYSPSVKGRFTISRENAKSTVNLQMNNLNPEDTAVYYCNTWSTWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:24)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:25)

• Minimal score value: -3.142
• Maximal score value: 1.1991
• Average score: -0.7853
• Total score value: -87.1703

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.6889
2	V	H	-1.0458
3	Q	H	-1.9156
4	L	H	0.0000
5	Q	H	-1.4157
6	E	H	0.0000
7	S	H	-0.9770
8	G	H	-1.1175
9	G	H	-0.5943
11	G	H	0.1366
12	L	H	1.1503
13	V	H	0.0940
14	Q	H	-1.3401
15	P	H	-1.7056
16	G	H	-1.6884
17	G	H	-1.1222
18	S	H	-1.2861
19	L	H	-0.8749
20	R	H	-1.9124
21	L	H	0.0000
22	S	H	-0.6990
23	C	H	0.0000
24	V	H	-0.2388
25	L	H	0.0000
26	S	H	-1.2175
27	N	H	-1.4923
28	G	H	-0.5909
29	I	H	1.1991
30	F	H	0.0000
35	S	H	-0.5097
36	T	H	0.2088
37	Y	H	0.6134
38	G	H	0.0239
39	M	H	0.0000
40	N	H	0.0000
41	W	H	0.0000
42	Y	H	-0.2845
43	R	H	-1.3038
44	Q	H	-1.9941
45	A	H	0.0000
46	P	H	-1.4900
47	G	H	-1.7919
48	K	H	-3.1420
49	Q	H	-3.0626
50	R	H	-2.6282
51	E	H	-2.6386
52	F	H	-0.7955
53	V	H	0.0000
54	A	H	0.0000
55	S	H	-0.3236
56	I	H	0.0000
57	T	H	-0.5076
58	S	H	-0.7973
59	S	H	-0.6671
63	G	H	-1.1220
64	S	H	-0.8190
65	T	H	-0.9187
66	N	H	-1.5837
67	Y	H	-1.0795
68	S	H	0.0000
69	P	H	-1.0537
70	S	H	-1.0211
71	V	H	0.0000
72	K	H	-2.2493
74	G	H	-1.6389
75	R	H	-1.6188
76	F	H	0.0000
77	T	H	-1.0048
78	I	H	0.0000
79	S	H	-0.8915
80	R	H	-1.8208
81	E	H	-2.8171
82	N	H	-2.2291
83	A	H	-1.7744
84	K	H	-2.4460
85	S	H	-1.2964
86	T	H	-1.2844
87	V	H	0.0000
88	N	H	-0.9981
89	L	H	0.0000
90	Q	H	-1.1486
91	M	H	0.0000
92	N	H	-1.6467
93	N	H	-2.1079
94	L	H	0.0000
95	N	H	-1.7972
96	P	H	-1.5581
97	E	H	-2.1169
98	D	H	0.0000
99	T	H	-0.7486
100	A	H	0.0000
101	V	H	-0.3607
102	Y	H	0.0000
103	Y	H	-0.3056
104	C	H	0.0000
105	N	H	0.0000
106	T	H	0.0000
107	W	H	1.1768
116	S	H	0.4639
117	T	H	0.2423
118	W	H	0.0869
119	G	H	-0.8499
120	Q	H	-1.5092
121	G	H	-0.8988
122	T	H	-0.8745
123	Q	H	-0.6305
124	V	H	0.0000
125	T	H	-0.1078
126	V	H	0.0000
127	S	H	-0.6139
128	S	H	-0.7646