Project name: CM142-148 (1)

Chain sequence(s)	A: GVSHWM; C: GVSHWM; B: GVSHWM; E: GVSHWM; D: GVSHWM; G: GVSHWM; F: GVSHWM; I: GVSHWM; H: GVSHWM; J: GVSHWM
Selected Chain(s)	A,C,B,E,D,G,F,I,H,J
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:18)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:21)

• Minimal score value: -0.9409
• Maximal score value: 2.0668
• Average score: 0.6122
• Total score value: 36.7317

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	G	C	-0.7742
3	V	C	0.0000
4	S	C	-0.0222
5	H	C	0.0000
6	W	C	1.7009
7	M	C	2.0578
2	G	A	-0.4877
3	V	A	-0.0001
4	S	A	0.0152
5	H	A	0.7605
6	W	A	1.8630
7	M	A	2.0155
2	G	B	-0.6512
3	V	B	-0.3277
4	S	B	-0.0794
5	H	B	0.8408
6	W	B	1.9172
7	M	B	2.0573
2	G	E	-0.9366
3	V	E	0.0000
4	S	E	-0.1281
5	H	E	0.0000
6	W	E	1.7411
7	M	E	1.9994
2	G	D	-0.8659
3	V	D	0.0000
4	S	D	-0.0840
5	H	D	0.0000
6	W	D	1.8048
7	M	D	2.0465
2	G	F	-0.9409
3	V	F	0.0000
4	S	F	-0.1777
5	H	F	0.0000
6	W	F	1.6656
7	M	F	2.0668
2	G	G	-0.7308
3	V	G	0.0000
4	S	G	0.0772
5	H	G	0.0000
6	W	G	1.7622
7	M	G	1.9641
2	G	I	-0.4249
3	V	I	0.1121
4	S	I	0.1524
5	H	I	0.9486
6	W	I	1.6105
7	M	I	1.8469
2	G	H	-0.4147
3	V	H	0.0000
4	S	H	0.3646
5	H	H	0.0000
6	W	H	1.6292
7	M	H	1.8690
2	G	J	0.1416
3	V	J	1.2688
4	S	J	0.7249
5	H	J	1.0318
6	W	J	1.7957
7	M	J	1.9258