Project name: e219d9a05e91374

Chain sequence(s)	A: QVQLVESGGGSVQAGGSLRLSCTASGFTFSSFGLGWFRQAPGQEREAVAAISSGSSTIYYADSVKGRFTISRDNAKNTVTLQMNNLKPEDTAIYYCAREGGYYYGRSYYTMDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:31)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:32)

• Minimal score value: -3.2616
• Maximal score value: 2.037
• Average score: -0.5826
• Total score value: -72.2437

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.3082
2	V	A	-0.4762
3	Q	A	-0.3743
4	L	A	0.0000
5	V	A	1.2164
6	E	A	0.0000
7	S	A	-0.4868
8	G	A	-1.2232
9	G	A	-1.1538
10	G	A	-0.9383
11	S	A	-0.7294
12	V	A	-0.8995
13	Q	A	-1.8477
14	A	A	-2.0482
15	G	A	-1.9363
16	G	A	-1.4761
17	S	A	-1.5225
18	L	A	-1.2085
19	R	A	-2.1205
20	L	A	0.0000
21	S	A	-0.4912
22	C	A	0.0000
23	T	A	-0.1303
24	A	A	0.0000
25	S	A	-0.5789
26	G	A	-0.8006
27	F	A	-0.2461
28	T	A	-0.2101
29	F	A	0.0000
30	S	A	-0.7138
31	S	A	-0.4021
32	F	A	0.0960
33	G	A	0.0000
34	L	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	F	A	-0.1906
38	R	A	0.0000
39	Q	A	-1.7023
40	A	A	-1.7035
41	P	A	-1.1723
42	G	A	-1.6668
43	Q	A	-2.7966
44	E	A	-3.2616
45	R	A	-2.5083
46	E	A	-2.1506
47	A	A	-0.5104
48	V	A	0.0000
49	A	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	S	A	-0.0023
53	S	A	-0.5808
54	G	A	-0.8330
55	S	A	-0.4894
56	S	A	-0.2066
57	T	A	0.4562
58	I	A	1.5419
59	Y	A	1.0249
60	Y	A	-0.1743
61	A	A	-1.1854
62	D	A	-2.3237
63	S	A	-1.7020
64	V	A	0.0000
65	K	A	-2.4929
66	G	A	-1.8811
67	R	A	-1.6355
68	F	A	0.0000
69	T	A	-0.5956
70	I	A	0.0000
71	S	A	-0.3328
72	R	A	-1.2114
73	D	A	-1.7809
74	N	A	-1.9882
75	A	A	-1.5030
76	K	A	-2.3574
77	N	A	-1.7518
78	T	A	-1.0856
79	V	A	0.0000
80	T	A	-0.7534
81	L	A	0.0000
82	Q	A	-1.1717
83	M	A	0.0000
84	N	A	-1.9787
85	N	A	-2.4194
86	L	A	0.0000
87	K	A	-2.9413
88	P	A	-2.0478
89	E	A	-2.4205
90	D	A	0.0000
91	T	A	-1.1675
92	A	A	0.0000
93	I	A	-0.3042
94	Y	A	0.0000
95	Y	A	-0.0498
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	E	A	0.3180
100	G	A	0.4262
101	G	A	0.7967
102	Y	A	1.9900
103	Y	A	2.0370
104	Y	A	1.4712
105	G	A	-0.0353
106	R	A	-0.6804
107	S	A	0.5196
108	Y	A	1.6106
109	Y	A	1.5797
110	T	A	0.8252
111	M	A	0.2162
112	D	A	-0.5050
113	Y	A	0.4061
114	W	A	0.5158
115	G	A	0.1956
116	Q	A	-0.7363
117	G	A	0.0000
118	T	A	-0.6476
119	Q	A	-1.2223
120	V	A	0.0000
121	T	A	-1.0320
122	V	A	0.0000
123	S	A	-1.3101
124	S	A	-0.9644