Project name: e22a1c58c7e195c

Chain sequence(s)	A: IVIVKGH; C: IVIVKGH; B: IVIVKGH; E: IVIVKGH; D: IVIVKGH; G: IVIVKGH; F: IVIVKGH; I: IVIVKGH; H: IVIVKGH; K: IVIVKGH; J: IVIVKGH; M: IVIVKGH; L: IVIVKGH; O: IVIVKGH; N: IVIVKGH; Q: IVIVKGH; P: IVIVKGH; S: IVIVKGH; R: IVIVKGH; T: IVIVKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:26)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:31)

• Minimal score value: -2.5264
• Maximal score value: 4.0552
• Average score: 0.2493
• Total score value: 34.901

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	I	A	2.5677
2	V	A	0.0000
3	I	A	1.0155
4	V	A	0.0000
5	K	A	-1.8063
6	G	A	-1.8127
7	H	A	-2.3573
1	I	B	2.6315
2	V	B	0.0000
3	I	B	1.0673
4	V	B	0.0000
5	K	B	-2.0070
6	G	B	-2.0010
7	H	B	-2.4707
1	I	C	2.8178
2	V	C	2.2973
3	I	C	1.1888
4	V	C	0.0429
5	K	C	-1.9577
6	G	C	-1.7386
7	H	C	-2.1547
1	I	D	3.6375
2	V	D	4.0552
3	I	D	3.0763
4	V	D	1.9822
5	K	D	-1.0241
6	G	D	-1.7077
7	H	D	-2.1666
1	I	E	2.8438
2	V	E	3.6880
3	I	E	0.0000
4	V	E	1.8363
5	K	E	-0.2401
6	G	E	-1.5054
7	H	E	-2.4222
1	I	F	2.2311
2	V	F	2.6605
3	I	F	0.0000
4	V	F	1.8603
5	K	F	0.0000
6	G	F	-1.0670
7	H	F	-2.1869
1	I	G	2.0416
2	V	G	2.5197
3	I	G	0.0000
4	V	G	1.7906
5	K	G	0.0000
6	G	G	-0.9649
7	H	G	-2.1342
1	I	H	2.0355
2	V	H	2.5187
3	I	H	0.0000
4	V	H	1.7356
5	K	H	0.0000
6	G	H	-1.0138
7	H	H	-2.1655
1	I	I	2.0612
2	V	I	2.5388
3	I	I	0.0000
4	V	I	1.6557
5	K	I	0.1753
6	G	I	-1.0956
7	H	I	-2.1843
1	I	J	2.0758
2	V	J	2.5529
3	I	J	0.0000
4	V	J	1.5886
5	K	J	0.0451
6	G	J	-1.1473
7	H	J	-2.1975
1	I	K	2.0562
2	V	K	2.5489
3	I	K	0.0000
4	V	K	1.5679
5	K	K	0.0372
6	G	K	-1.1622
7	H	K	-2.1899
1	I	L	2.3613
2	V	L	2.6505
3	I	L	0.0000
4	V	L	1.7243
5	K	L	0.0435
6	G	L	-1.1756
7	H	L	-2.1816
1	I	M	2.7954
2	V	M	3.4169
3	I	M	0.0000
4	V	M	1.8922
5	K	M	0.1327
6	G	M	-1.2290
7	H	M	-2.2775
1	I	N	3.4271
2	V	N	3.9508
3	I	N	2.8590
4	V	N	2.0905
5	K	N	-0.2992
6	G	N	-1.2745
7	H	N	-2.0379
1	I	O	3.2770
2	V	O	0.0000
3	I	O	2.2842
4	V	O	0.0000
5	K	O	-2.0901
6	G	O	-1.7182
7	H	O	-2.1038
1	I	P	3.8738
2	V	P	0.0000
3	I	P	1.6572
4	V	P	0.0000
5	K	P	-1.9352
6	G	P	-2.1970
7	H	P	-2.5264
1	I	Q	3.2489
2	V	Q	0.0000
3	I	Q	1.4056
4	V	Q	0.0000
5	K	Q	-1.7046
6	G	Q	-1.7356
7	H	Q	-2.3772
1	I	R	2.9748
2	V	R	0.0000
3	I	R	1.1519
4	V	R	0.0000
5	K	R	-1.4362
6	G	R	-1.6664
7	H	R	-2.3302
1	I	S	2.6025
2	V	S	0.0000
3	I	S	1.0886
4	V	S	0.0000
5	K	S	-1.6764
6	G	S	-1.7527
7	H	S	-2.3395
1	I	T	2.5650
2	V	T	0.0000
3	I	T	1.0338
4	V	T	0.0000
5	K	T	-1.5764
6	G	T	-1.7629
7	H	T	-2.3665