Project name: e2963fe143db11b

Chain sequence(s)	A: GGGGSGGGGSGGGGS; C: GGGGSGGGGSGGGGS; B: GGGGSGGGGSGGGGS; E: GGGGSGGGGSGGGGS; D: GGGGSGGGGSGGGGS; G: GGGGSGGGGSGGGGS; F: GGGGSGGGGSGGGGS; I: GGGGSGGGGSGGGGS; H: GGGGSGGGGSGGGGS; K: GGGGSGGGGSGGGGS; J: GGGGSGGGGSGGGGS; L: GGGGSGGGGSGGGGS
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:05)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:08)

• Minimal score value: -1.911
• Maximal score value: 0.0
• Average score: -0.9608
• Total score value: -172.95

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.5861
2	G	A	-1.5660
3	G	A	-1.1408
4	G	A	-0.8497
5	S	A	-0.7016
6	G	A	-0.7824
7	G	A	-0.8399
8	G	A	-0.7791
9	G	A	-0.7008
10	S	A	-0.6311
11	G	A	-0.7003
12	G	A	-0.8126
13	G	A	0.0000
14	G	A	-1.0195
15	S	A	-0.9172
1	G	B	-1.4686
2	G	B	-1.5698
3	G	B	0.0000
4	G	B	-0.8948
5	S	B	0.0000
6	G	B	-0.8597
7	G	B	-1.0917
8	G	B	0.0000
9	G	B	-0.8773
10	S	B	0.0000
11	G	B	-0.8197
12	G	B	-0.8796
13	G	B	0.0000
14	G	B	0.0000
15	S	B	-1.1845
1	G	C	-1.1587
2	G	C	-1.2452
3	G	C	-1.2753
4	G	C	-0.8108
5	S	C	-0.8617
6	G	C	-0.9229
7	G	C	-1.0370
8	G	C	-1.2191
9	G	C	-0.9189
10	S	C	-0.8255
11	G	C	-0.9401
12	G	C	-0.9395
13	G	C	-1.2974
14	G	C	-1.4741
15	S	C	-1.1029
1	G	D	-1.4160
2	G	D	-1.3268
3	G	D	-1.4260
4	G	D	0.0000
5	S	D	-1.0564
6	G	D	-1.1165
7	G	D	-1.1842
8	G	D	-1.3352
9	G	D	-1.2397
10	S	D	-1.0764
11	G	D	-1.1712
12	G	D	0.0000
13	G	D	-1.4917
14	G	D	-1.5798
15	S	D	-1.1745
1	G	E	-1.2600
2	G	E	-1.2447
3	G	E	-1.3738
4	G	E	-1.2336
5	S	E	-0.9302
6	G	E	-1.1629
7	G	E	-1.1214
8	G	E	-1.1949
9	G	E	-1.1750
10	S	E	-0.9106
11	G	E	-1.1785
12	G	E	-1.1060
13	G	E	-1.2501
14	G	E	-1.3868
15	S	E	-0.8851
1	G	F	-1.5830
2	G	F	-1.4592
3	G	F	-1.4845
4	G	F	0.0000
5	S	F	-0.9193
6	G	F	0.0000
7	G	F	-1.0616
8	G	F	-1.2461
9	G	F	0.0000
10	S	F	-0.8984
11	G	F	-0.9496
12	G	F	0.0000
13	G	F	-1.1603
14	G	F	0.0000
15	S	F	-1.0933
1	G	G	-1.5259
2	G	G	-1.2345
3	G	G	-1.2486
4	G	G	0.0000
5	S	G	-0.6143
6	G	G	-0.7107
7	G	G	-0.7415
8	G	G	-0.9555
9	G	G	0.0000
10	S	G	-0.5741
11	G	G	-0.6892
12	G	G	0.0000
13	G	G	-0.8989
14	G	G	-1.0850
15	S	G	-0.8767
1	G	H	-1.7572
2	G	H	-1.5378
3	G	H	-1.3000
4	G	H	0.0000
5	S	H	-0.6308
6	G	H	0.0000
7	G	H	-0.8359
8	G	H	-0.8401
9	G	H	0.0000
10	S	H	-0.5708
11	G	H	-0.7470
12	G	H	0.0000
13	G	H	-0.9001
14	G	H	-0.9985
15	S	H	-0.8651
1	G	I	-1.8533
2	G	I	-1.6824
3	G	I	-1.6076
4	G	I	0.0000
5	S	I	-0.9554
6	G	I	-1.0734
7	G	I	-1.1064
8	G	I	-1.1842
9	G	I	0.0000
10	S	I	-0.9200
11	G	I	-1.0878
12	G	I	-1.1580
13	G	I	-1.1927
14	G	I	0.0000
15	S	I	-0.8601
1	G	J	-1.4995
2	G	J	-1.5708
3	G	J	-1.6418
4	G	J	-1.1250
5	S	J	-1.0089
6	G	J	-1.0307
7	G	J	-1.2112
8	G	J	-1.3218
9	G	J	-1.0801
10	S	J	-1.0598
11	G	J	-1.1520
12	G	J	-1.2023
13	G	J	-1.3505
14	G	J	-1.0440
15	S	J	-0.6972
1	G	K	-1.6118
2	G	K	-1.9110
3	G	K	-1.5609
4	G	K	-1.2462
5	S	K	-1.1025
6	G	K	-1.0756
7	G	K	-1.2962
8	G	K	-1.1397
9	G	K	-1.1663
10	S	K	-1.0811
11	G	K	-1.1273
12	G	K	-1.3311
13	G	K	-1.3232
14	G	K	-1.0826
15	S	K	-0.8207
1	G	L	-1.7523
2	G	L	-1.8373
3	G	L	-1.2859
4	G	L	-1.0597
5	S	L	-0.8941
6	G	L	-0.9825
7	G	L	-1.0666
8	G	L	-0.8712
9	G	L	-0.9572
10	S	L	0.0000
11	G	L	-0.8774
12	G	L	-1.1516
13	G	L	0.0000
14	G	L	-1.0481
15	S	L	-0.9096