Project name: 22-4.pdb

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCAASGSISSHNDMSWYRQAPGNQLELVSFIASGGSTYYADSVKGRFTISRDHAKNTLYLQMNSLRAEDTAVYYCNSRTYDGEKTYWGQGTTVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:54)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:54)

• Minimal score value: -2.6299
• Maximal score value: 1.2439
• Average score: -0.6304
• Total score value: -73.7576

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5028
2	V	H	-0.9911
3	Q	H	-1.0878
4	L	H	0.0000
5	V	H	1.1088
6	E	H	0.2864
7	S	H	-0.3658
8	G	H	-0.7835
9	G	H	-0.2288
11	G	H	0.4515
12	L	H	1.2439
13	V	H	0.0337
14	Q	H	-1.3374
15	P	H	-1.3922
16	G	H	-1.3852
17	G	H	-0.9400
18	S	H	-0.9719
19	L	H	-0.3681
20	R	H	-1.1283
21	L	H	0.0000
22	S	H	-0.1870
23	C	H	0.0000
24	A	H	-0.0812
25	A	H	-0.3753
26	S	H	-0.5656
27	G	H	-0.7623
28	S	H	-0.7774
29	I	H	0.0000
30	S	H	-1.2582
35	S	H	-1.1517
36	H	H	-1.2529
37	N	H	-0.9174
38	D	H	-0.8642
39	M	H	0.0000
40	S	H	0.0000
41	W	H	0.0000
42	Y	H	0.4585
43	R	H	0.0000
44	Q	H	-0.9166
45	A	H	-1.3024
46	P	H	-1.1069
47	G	H	-1.4573
48	N	H	-2.2198
49	Q	H	-1.8316
50	L	H	-0.4122
51	E	H	-0.5630
52	L	H	0.5925
53	V	H	0.0000
54	S	H	0.0000
55	F	H	0.7129
56	I	H	0.0000
57	A	H	-0.6200
58	S	H	-1.1775
59	G	H	-1.0040
63	G	H	-0.6493
64	S	H	-0.2007
65	T	H	0.4840
66	Y	H	1.0798
67	Y	H	-0.0036
68	A	H	-0.8943
69	D	H	-2.3058
70	S	H	-1.7184
71	V	H	0.0000
72	K	H	-2.4041
74	G	H	-1.7503
75	R	H	-1.5969
76	F	H	0.0000
77	T	H	-0.5489
78	I	H	0.0000
79	S	H	-0.4454
80	R	H	-1.1487
81	D	H	-1.7622
82	H	H	-1.7928
83	A	H	-1.4356
84	K	H	-2.2649
85	N	H	-1.7275
86	T	H	0.0000
87	L	H	0.0000
88	Y	H	-0.4015
89	L	H	0.0000
90	Q	H	-0.8086
91	M	H	0.0000
92	N	H	-1.1924
93	S	H	-1.2105
94	L	H	0.0000
95	R	H	-2.2172
96	A	H	-1.6590
97	E	H	-2.1881
98	D	H	0.0000
99	T	H	-0.6315
100	A	H	0.0000
101	V	H	0.2143
102	Y	H	0.0000
103	Y	H	0.4665
104	C	H	0.0000
105	N	H	0.0000
106	S	H	0.0000
107	R	H	-1.0160
108	T	H	-1.1228
109	Y	H	-0.6605
110	D	H	-2.0497
113	G	H	-2.0666
114	E	H	-2.6299
115	K	H	-1.9783
116	T	H	-0.7507
117	Y	H	-0.3483
118	W	H	0.2229
119	G	H	-0.0223
120	Q	H	-0.8138
121	G	H	-0.2006
122	T	H	-0.1551
123	T	H	-0.0005
124	V	H	0.0000
125	T	H	0.0153
126	V	H	0.0000
127	S	H	-0.5631
128	S	H	-0.5048