Project name: e6cd1d279aad1dd

Chain sequence(s)	H: HLAQSGGGVVQPGRSLTLSCAASGFTFASSDMHWIRQGPGKGLEWVAVISFTGETKNYADSVRGRFTISRDNSRSTLHLQMYGLRADDTAVYYCASGPHHSGSGTYYPSYLYGWGPGAPVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:48)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:50)

• Minimal score value: -2.8201
• Maximal score value: 1.7421
• Average score: -0.4783
• Total score value: -59.3133

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
0	H	H	-1.0027
1	L	H	0.0000
2	A	H	-0.3794
3	Q	H	-0.4843
4	S	H	-0.6498
5	G	H	-0.6969
6	G	H	-0.2459
7	G	H	0.5022
8	V	H	1.5318
9	V	H	-0.0552
10	Q	H	-1.2742
11	P	H	-1.9889
12	G	H	-1.8688
13	R	H	-2.2618
14	S	H	-1.0172
15	L	H	-0.1043
16	T	H	-0.4015
17	L	H	0.0000
18	S	H	-0.5507
19	C	H	0.0000
20	A	H	-0.7381
21	A	H	-0.6391
22	S	H	-0.4818
23	G	H	-0.3489
24	F	H	0.5589
25	T	H	0.2011
26	F	H	0.0000
27	A	H	-0.0827
28	S	H	0.0360
29	S	H	0.1415
30	D	H	0.0000
31	M	H	0.0000
32	H	H	0.0000
33	W	H	0.0000
34	I	H	0.0000
35	R	H	0.0000
36	Q	H	-0.5790
37	G	H	-1.2441
38	P	H	-1.0259
39	G	H	-1.4718
40	K	H	-2.1526
41	G	H	-1.0873
42	L	H	0.4454
43	E	H	-0.3538
44	W	H	0.3713
45	V	H	0.0000
46	A	H	0.0000
47	V	H	-0.1311
48	I	H	0.0000
49	S	H	0.0000
50	F	H	0.2369
51	T	H	-0.6299
52	G	H	-1.2268
53	E	H	-1.9778
54	T	H	-1.3561
55	K	H	-1.4140
56	N	H	-1.4535
57	Y	H	-1.3880
58	A	H	-1.5436
59	D	H	-2.5503
60	S	H	-1.7722
61	V	H	0.0000
62	R	H	-2.8201
63	G	H	-1.5429
64	R	H	-0.9113
65	F	H	0.0000
66	T	H	-0.7784
67	I	H	0.0000
68	S	H	-1.0839
69	R	H	-1.4137
70	D	H	-2.1919
71	N	H	-1.8410
72	S	H	-1.7908
73	R	H	-2.5330
74	S	H	-1.5209
75	T	H	-1.3487
76	L	H	0.0000
77	H	H	-0.9246
78	L	H	0.0000
79	Q	H	-0.7397
80	M	H	0.0000
81	Y	H	0.0661
82	G	H	-0.9295
83	L	H	0.0000
84	R	H	-2.8155
85	A	H	-1.9290
86	D	H	-2.4166
87	D	H	0.0000
88	T	H	-0.8015
89	A	H	0.0000
90	V	H	0.2658
91	Y	H	0.0000
92	Y	H	0.3081
93	C	H	0.0000
94	A	H	0.0000
95	S	H	0.0000
96	G	H	0.0000
97	P	H	0.1649
98	H	H	-0.7876
99	H	H	-1.2299
100	S	H	-0.8611
101	G	H	-0.9080
102	S	H	-0.3529
103	G	H	-0.3143
104	T	H	0.5298
105	Y	H	1.1136
106	Y	H	1.5380
107	P	H	0.6693
108	S	H	0.7213
109	Y	H	1.4896
110	L	H	1.5142
111	Y	H	1.7421
112	G	H	0.8663
113	W	H	0.6018
114	G	H	-0.1664
115	P	H	-0.2866
116	G	H	-0.1708
117	A	H	0.0000
118	P	H	-0.0830
119	V	H	0.0000
120	T	H	0.0461
121	V	H	0.0000
122	S	H	-0.5459
123	S	H	-0.3059