Project name: e7bf0038599deab

Chain sequence(s)	A: QQKFQFQFEQQ; C: QQKFQFQFEQQ; B: QQKFQFQFEQQ; E: QQKFQFQFEQQ; D: QQKFQFQFEQQ; G: QQKFQFQFEQQ; F: QQKFQFQFEQQ; I: QQKFQFQFEQQ; H: QQKFQFQFEQQ; K: QQKFQFQFEQQ; J: QQKFQFQFEQQ; L: QQKFQFQFEQQ
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:06:49)
[INFO]       Main:     Simulation completed successfully.                                          (00:06:52)

• Minimal score value: -3.0768
• Maximal score value: 0.0
• Average score: -1.5352
• Total score value: -202.6477

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-2.3732
2	Q	A	0.0000
3	K	A	-2.1209
4	F	A	0.0000
5	Q	A	-1.8331
6	F	A	0.0000
7	Q	A	-1.9786
8	F	A	0.0000
9	E	A	-2.2451
10	Q	A	-2.0777
11	Q	A	-2.6112
1	Q	B	-2.6567
2	Q	B	0.0000
3	K	B	-2.3602
4	F	B	0.0000
5	Q	B	-1.9584
6	F	B	0.0000
7	Q	B	-1.9056
8	F	B	0.0000
9	E	B	0.0000
10	Q	B	-2.0581
11	Q	B	-2.6142
1	Q	C	-3.0039
2	Q	C	0.0000
3	K	C	-3.0039
4	F	C	0.0000
5	Q	C	-1.9313
6	F	C	0.0000
7	Q	C	-1.6662
8	F	C	0.0000
9	E	C	0.0000
10	Q	C	-2.1134
11	Q	C	-2.7514
1	Q	D	-2.2752
2	Q	D	-2.0496
3	K	D	-1.7789
4	F	D	-0.3950
5	Q	D	-1.2867
6	F	D	-0.3943
7	Q	D	-1.6556
8	F	D	-1.3170
9	E	D	-2.9378
10	Q	D	-2.9980
11	Q	D	-2.8282
1	Q	E	-2.2521
2	Q	E	-1.9952
3	K	E	-1.8829
4	F	E	-0.4239
5	Q	E	-1.3615
6	F	E	-0.6270
7	Q	E	-1.7332
8	F	E	-1.3826
9	E	E	-2.8981
10	Q	E	-3.0103
11	Q	E	-2.8315
1	Q	F	-3.0768
2	Q	F	0.0000
3	K	F	-2.8705
4	F	F	0.0000
5	Q	F	-1.8095
6	F	F	0.0000
7	Q	F	-1.5667
8	F	F	0.0000
9	E	F	-2.0066
10	Q	F	-2.0554
11	Q	F	-2.7149
1	Q	G	-2.5989
2	Q	G	0.0000
3	K	G	-2.1907
4	F	G	0.0000
5	Q	G	-1.6269
6	F	G	0.0000
7	Q	G	-1.6560
8	F	G	0.0000
9	E	G	0.0000
10	Q	G	-2.0624
11	Q	G	-2.6747
1	Q	H	-2.5950
2	Q	H	0.0000
3	K	H	-2.1115
4	F	H	0.0000
5	Q	H	-1.6912
6	F	H	0.0000
7	Q	H	-1.7772
8	F	H	0.0000
9	E	H	-2.2420
10	Q	H	-2.1969
11	Q	H	-2.7202
1	Q	I	-3.0107
2	Q	I	-2.7206
3	K	I	-2.9883
4	F	I	0.0000
5	Q	I	-1.8383
6	F	I	0.0000
7	Q	I	-1.5473
8	F	I	0.0000
9	E	I	-2.0621
10	Q	I	-2.1871
11	Q	I	-2.8030
1	Q	J	-2.4212
2	Q	J	-2.2517
3	K	J	-2.0831
4	F	J	-0.2816
5	Q	J	-1.2059
6	F	J	-0.3263
7	Q	J	-1.6252
8	F	J	-1.3003
9	E	J	-2.8599
10	Q	J	-2.9803
11	Q	J	-2.8032
1	Q	K	-2.2612
2	Q	K	-2.0946
3	K	K	-2.0712
4	F	K	-0.6157
5	Q	K	-1.4060
6	F	K	-0.4761
7	Q	K	-1.6504
8	F	K	-1.2606
9	E	K	-2.7030
10	Q	K	-2.6997
11	Q	K	-2.5781
1	Q	L	-2.6321
2	Q	L	0.0000
3	K	L	-2.8076
4	F	L	0.0000
5	Q	L	-1.9061
6	F	L	0.0000
7	Q	L	-1.6170
8	F	L	0.0000
9	E	L	-2.0208
10	Q	L	-2.0822
11	Q	L	-2.6475