Project name: e88f4397feee93c

Chain sequence(s)	A: ELQLVESGGGLVQPGGSLRLSCAASRSIFGIYDMGWFRQAPGKEREWVSSVSNGVAFYADSVKGRFTISRDRAKNSVYLQMNSLRAEDTAVYYCRAVAHSTNTYWGQGTLVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:53)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:54)

• Minimal score value: -3.6296
• Maximal score value: 2.1614
• Average score: -0.5088
• Total score value: -58.5101

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.2354
2	L	A	-0.9407
3	Q	A	-0.5823
4	L	A	0.5279
5	V	A	1.3032
6	E	A	0.2930
7	S	A	-0.5269
8	G	A	-0.9464
9	G	A	0.0381
11	G	A	1.0441
12	L	A	1.7739
13	V	A	0.6692
14	Q	A	-1.1729
15	P	A	-1.2417
16	G	A	-1.4380
17	G	A	-1.3128
18	S	A	-1.3829
19	L	A	-1.2596
20	R	A	-2.5358
21	L	A	0.0000
22	S	A	-0.5351
23	C	A	0.0000
24	A	A	0.0213
25	A	A	-0.2977
26	S	A	-1.0041
27	R	A	-1.8137
28	S	A	-0.9000
29	I	A	0.3670
30	F	A	1.8108
35	G	A	0.9675
36	I	A	0.6076
37	Y	A	0.1612
38	D	A	0.0434
39	M	A	0.0000
40	G	A	0.0000
41	W	A	0.0000
42	F	A	0.1609
43	R	A	0.0000
44	Q	A	-1.8973
45	A	A	-1.7307
46	P	A	-1.4603
47	G	A	-1.8614
48	K	A	-3.4162
49	E	A	-3.6296
50	R	A	-2.6404
51	E	A	-1.8855
52	W	A	-0.3562
53	V	A	0.0000
54	S	A	0.0000
55	S	A	0.9365
56	V	A	0.0000
57	S	A	0.1720
58	N	A	-1.0621
63	G	A	-0.2868
64	V	A	1.5402
65	A	A	1.4989
66	F	A	2.1614
67	Y	A	0.1699
68	A	A	0.0000
69	D	A	-2.2842
70	S	A	-1.6857
71	V	A	0.0000
72	K	A	-2.1828
74	G	A	-1.7779
75	R	A	-1.9720
76	F	A	0.0000
77	T	A	-0.9556
78	I	A	0.0000
79	S	A	-0.4150
80	R	A	-1.2808
81	D	A	-1.7104
82	R	A	-2.1471
83	A	A	-1.5982
84	K	A	-2.3915
85	N	A	-1.6310
86	S	A	0.0000
87	V	A	0.0000
88	Y	A	-0.6847
89	L	A	0.0000
90	Q	A	-2.0666
91	M	A	0.0000
92	N	A	-2.4208
93	S	A	-1.5485
94	L	A	0.0000
95	R	A	-2.1347
96	A	A	-1.1735
97	E	A	-1.5898
98	D	A	0.0000
99	T	A	-0.1322
100	A	A	0.0000
101	V	A	0.7107
102	Y	A	0.0000
103	Y	A	0.0823
104	C	A	0.0000
105	R	A	0.1574
106	A	A	0.0000
107	V	A	0.0406
108	A	A	0.0000
109	H	A	-0.9731
113	S	A	-0.7582
114	T	A	-0.7745
115	N	A	-0.8185
116	T	A	-0.1287
117	Y	A	0.3843
118	W	A	0.4841
119	G	A	-0.0369
120	Q	A	-0.8665
121	G	A	-0.2458
122	T	A	0.4155
123	L	A	1.7993
124	V	A	0.0000
125	T	A	0.5537
126	V	A	-0.2005
127	S	A	-0.2842
128	S	A	-0.1836