Project name: e8fc5be971fe389

Chain sequence(s)	A: LMFHASDDDEILDYFDYLFDFWFKSSLNWDREKHHKFWFHVFFEDFFFAEHFDFSKFLVFFFWFFFDHVIWGPFWHLTFRGDRNYFARWPDLFKDFFDYYEQL
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:03)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:04)

• Minimal score value: -3.9039
• Maximal score value: 3.2083
• Average score: -0.1558
• Total score value: -16.0477

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	L	A	2.2753
2	M	A	2.1777
3	F	A	2.4912
4	H	A	0.1705
5	A	A	-0.3902
6	S	A	-1.8999
7	D	A	-3.6343
8	D	A	-3.8481
9	D	A	-3.8285
10	E	A	-3.8963
11	I	A	-1.9950
12	L	A	-1.2234
13	D	A	-2.3722
14	Y	A	0.0000
15	F	A	-0.0330
16	D	A	-1.4221
17	Y	A	-0.2043
18	L	A	0.0000
19	F	A	0.0358
20	D	A	-0.8304
21	F	A	0.0262
22	W	A	0.4258
23	F	A	0.7109
24	K	A	-0.4442
25	S	A	-0.5296
26	S	A	0.3081
27	L	A	0.9998
28	N	A	-0.5793
29	W	A	-0.6254
30	D	A	-2.2680
31	R	A	-3.5719
32	E	A	-3.9039
33	K	A	-3.4528
34	H	A	0.0000
35	H	A	-2.2168
36	K	A	-2.2707
37	F	A	-1.1486
38	W	A	0.0000
39	F	A	0.0000
40	H	A	-0.7969
41	V	A	0.0000
42	F	A	0.4739
43	F	A	0.0000
44	E	A	-1.1771
45	D	A	-0.8250
46	F	A	0.0000
47	F	A	1.6374
48	F	A	1.5701
49	A	A	-0.1249
50	E	A	-0.8532
51	H	A	0.3600
52	F	A	1.6392
53	D	A	0.0000
54	F	A	2.2198
55	S	A	0.8080
56	K	A	0.9000
57	F	A	2.1074
58	L	A	2.5350
59	V	A	0.0000
60	F	A	0.0000
61	F	A	3.2083
62	F	A	2.7208
63	W	A	0.0000
64	F	A	2.2095
65	F	A	2.4827
66	F	A	2.1589
67	D	A	0.0000
68	H	A	0.0000
69	V	A	2.0821
70	I	A	2.4943
71	W	A	1.9145
72	G	A	0.0000
73	P	A	0.0000
74	F	A	2.2735
75	W	A	1.6842
76	H	A	0.0864
77	L	A	0.1465
78	T	A	0.8022
79	F	A	1.3229
80	R	A	-1.1179
81	G	A	-1.1540
82	D	A	-1.4990
83	R	A	-2.3874
84	N	A	-1.9077
85	Y	A	-0.3078
86	F	A	0.4000
87	A	A	-0.5368
88	R	A	-1.0105
89	W	A	-0.3474
90	P	A	-0.9763
91	D	A	-1.9167
92	L	A	0.0000
93	F	A	0.3995
94	K	A	-1.1089
95	D	A	-1.1295
96	F	A	0.4702
97	F	A	0.9613
98	D	A	-0.4662
99	Y	A	-0.1953
100	Y	A	0.3357
101	E	A	-1.2271
102	Q	A	-0.9401
103	L	A	0.5213