Project name: e93c67a80a1e5ca

Chain sequence(s)	A: HNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLAD
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:56)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:57)

• Minimal score value: -3.18
• Maximal score value: 2.1459
• Average score: -0.6518
• Total score value: -73.6571

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
19	H	A	-1.8244
20	N	A	-1.7976
21	T	A	-0.6296
22	T	A	0.2203
23	V	A	1.0852
24	F	A	0.1417
25	Q	A	-0.6623
26	G	A	0.0000
27	V	A	-0.6718
28	A	A	-1.5036
29	G	A	-1.8447
30	Q	A	-2.2481
31	S	A	-2.2146
32	L	A	0.0000
33	Q	A	-1.6308
34	V	A	0.0000
35	S	A	-0.4784
36	C	A	0.0000
37	P	A	-0.8928
38	Y	A	-1.1153
39	D	A	-1.8004
40	S	A	-0.7389
41	M	A	0.0114
42	K	A	-1.6639
43	H	A	0.0000
44	W	A	0.0838
45	G	A	-0.1913
46	R	A	-0.9518
47	R	A	-0.7917
48	K	A	0.0000
49	A	A	0.0000
50	W	A	0.0000
51	C	A	0.0000
52	R	A	-0.8546
53	Q	A	0.0000
54	L	A	-0.1267
55	G	A	-1.3508
56	E	A	-2.5855
57	K	A	-2.6065
58	G	A	-1.5330
59	P	A	-1.0969
60	C	A	-1.0314
61	Q	A	-1.4739
62	R	A	-1.3416
63	V	A	-0.7201
64	V	A	0.0000
65	S	A	-0.8234
66	T	A	0.0000
67	H	A	-0.2149
68	N	A	-0.8242
69	L	A	0.5788
70	W	A	1.0937
71	L	A	2.1459
72	L	A	1.6491
73	S	A	0.0000
74	F	A	1.8928
75	L	A	0.9225
76	R	A	-0.9410
77	R	A	-1.1375
78	W	A	-0.7019
79	N	A	-1.2836
80	G	A	-1.2598
81	S	A	-1.5245
82	T	A	-1.2658
83	A	A	0.0000
84	I	A	0.0000
85	T	A	-0.2605
86	D	A	0.0000
87	D	A	-0.7139
88	T	A	0.3387
89	L	A	1.0207
90	G	A	-0.4261
91	G	A	0.0000
92	T	A	-0.8378
93	L	A	0.0000
94	T	A	-0.6442
95	I	A	0.0000
96	T	A	0.0000
97	L	A	0.0000
98	R	A	-3.1800
99	N	A	-2.9067
100	L	A	0.0000
101	Q	A	-2.0718
102	P	A	-1.1259
103	H	A	-1.6414
104	D	A	-1.4973
105	A	A	-0.8297
106	G	A	0.0084
107	L	A	0.2486
108	Y	A	0.0000
109	Q	A	-0.7648
110	C	A	0.0000
111	Q	A	0.0000
112	S	A	0.0000
113	L	A	-1.7036
114	H	A	-2.3203
115	G	A	-1.6847
116	S	A	-1.5462
117	E	A	-2.7051
118	A	A	-2.1024
119	D	A	-2.2877
120	T	A	-1.2286
121	L	A	0.0000
122	R	A	-1.3872
123	K	A	-0.8589
124	V	A	0.0000
125	L	A	0.6361
126	V	A	0.0000
127	E	A	-0.4198
128	V	A	-0.5137
129	L	A	0.1713
130	A	A	-0.3634
131	D	A	-1.5348