Project name: ec259401b71cb58

Chain sequence(s)	A: GGGHKFG; C: GGGHKFG; B: GGGHKFG; E: GGGHKFG; D: GGGHKFG; G: GGGHKFG; F: GGGHKFG; I: GGGHKFG; H: GGGHKFG; K: GGGHKFG; J: GGGHKFG; M: GGGHKFG; L: GGGHKFG; O: GGGHKFG; N: GGGHKFG; Q: GGGHKFG; P: GGGHKFG; S: GGGHKFG; R: GGGHKFG; T: GGGHKFG
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:56)
[INFO]       Main:     Simulation completed successfully.                                          (00:05:01)

• Minimal score value: -2.8372
• Maximal score value: 0.0
• Average score: -1.477
• Total score value: -206.7808

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.2348
2	G	A	-1.2541
3	G	A	-1.5408
4	H	A	-1.7300
5	K	A	-2.3687
6	F	A	0.0000
7	G	A	-1.4626
1	G	B	-1.2229
2	G	B	-1.2447
3	G	B	-1.4784
4	H	B	-1.5971
5	K	B	-2.1491
6	F	B	0.0000
7	G	B	-1.3903
1	G	C	-1.2350
2	G	C	-1.2576
3	G	C	-1.5181
4	H	C	-1.6692
5	K	C	-2.2703
6	F	C	0.0000
7	G	C	-1.4323
1	G	D	-1.2530
2	G	D	-1.2843
3	G	D	-1.5639
4	H	D	-1.7589
5	K	D	-2.4217
6	F	D	0.0000
7	G	D	-1.4647
1	G	E	-1.2504
2	G	E	-1.3346
3	G	E	-1.6250
4	H	E	-1.8749
5	K	E	-2.5265
6	F	E	0.0000
7	G	E	-1.4975
1	G	F	-1.2867
2	G	F	-1.4789
3	G	F	-2.0721
4	H	F	-2.3011
5	K	F	-2.7987
6	F	F	0.0000
7	G	F	-1.3983
1	G	G	-1.1580
2	G	G	-1.4028
3	G	G	-2.1254
4	H	G	-2.4541
5	K	G	-2.7353
6	F	G	-1.3922
7	G	G	-1.0416
1	G	H	-1.1512
2	G	H	-1.3741
3	G	H	-2.0441
4	H	H	-2.3895
5	K	H	-2.7262
6	F	H	-1.8172
7	G	H	-1.0485
1	G	I	-1.2670
2	G	I	-1.4433
3	G	I	-1.9979
4	H	I	-2.2602
5	K	I	-2.6452
6	F	I	0.0000
7	G	I	-1.4601
1	G	J	-1.2222
2	G	J	-1.3165
3	G	J	-1.5435
4	H	J	-1.7473
5	K	J	-2.3595
6	F	J	0.0000
7	G	J	-1.4179
1	G	K	-1.2281
2	G	K	-1.2383
3	G	K	-1.5076
4	H	K	-1.6514
5	K	K	-2.2103
6	F	K	0.0000
7	G	K	-1.4277
1	G	L	-1.2470
2	G	L	-1.2612
3	G	L	-1.5458
4	H	L	-1.7149
5	K	L	-2.3895
6	F	L	0.0000
7	G	L	-1.4703
1	G	M	-1.2653
2	G	M	-1.2957
3	G	M	-1.5703
4	H	M	-1.7240
5	K	M	-2.2960
6	F	M	0.0000
7	G	M	-1.4354
1	G	N	-1.3058
2	G	N	-1.3656
3	G	N	-1.6622
4	H	N	-1.8981
5	K	N	-2.5842
6	F	N	0.0000
7	G	N	-1.4458
1	G	O	-1.3153
2	G	O	-1.5198
3	G	O	-2.0416
4	H	O	-2.1581
5	K	O	-2.4122
6	F	O	0.0000
7	G	O	-1.1452
1	G	P	-1.2788
2	G	P	-1.3091
3	G	P	-1.6132
4	H	P	-1.7785
5	K	P	-2.4753
6	F	P	0.0000
7	G	P	-1.4850
1	G	Q	-1.3030
2	G	Q	-1.4949
3	G	Q	-2.0199
4	H	Q	-2.2368
5	K	Q	-2.8372
6	F	Q	0.0000
7	G	Q	-1.4676
1	G	R	-1.0475
2	G	R	-1.5232
3	G	R	-1.9633
4	H	R	-2.3098
5	K	R	-2.6114
6	F	R	-1.4770
7	G	R	-1.0677
1	G	S	-1.0534
2	G	S	-1.5435
3	G	S	-1.9623
4	H	S	-2.2394
5	K	S	-2.2369
6	F	S	-0.5551
7	G	S	-0.5632
1	G	T	-1.2225
2	G	T	-1.2383
3	G	T	-1.4988
4	H	T	-1.5793
5	K	T	-2.2529
6	F	T	0.0000
7	G	T	-1.4153