Project name: f3667fe796b69b7

Chain sequence(s)	H: EVQLVESGGGVVQPGGSLKLSCVASGTDFSINFIRWYRQAPGKQREFVAGFTATGNTNYADSMKGRFTISRDNTKNAVYLQIDSLKPEDTAVYYCYMLDKWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	5 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:02)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:08:00)
[INFO]       Main:     Simulation completed successfully.                                          (00:08:03)

• Minimal score value: -1.9991
• Maximal score value: 1.7722
• Average score: -0.3453
• Total score value: -38.3263

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.7625
2	V	H	-0.2987
3	Q	H	-1.1066
4	L	H	0.2862
5	V	H	1.7637
6	E	H	0.0433
7	S	H	-0.3165
9	G	H	-0.4256
10	G	H	-0.3173
11	G	H	0.1059
12	V	H	1.7722
13	V	H	0.2876
14	Q	H	-1.1949
15	P	H	-0.4671
16	G	H	-0.5330
17	G	H	-0.1837
18	S	H	-0.1994
19	L	H	-0.0521
20	K	H	-1.6820
21	L	H	0.0000
22	S	H	-0.0032
23	C	H	0.0000
24	V	H	0.9839
25	A	H	0.0000
26	S	H	-0.2719
27	G	H	-0.4744
29	T	H	-0.4710
30	D	H	-1.7992
31	F	H	0.0000
32	S	H	-0.1006
33	I	H	0.3379
39	N	H	-0.6522
40	F	H	0.7248
41	I	H	0.0000
42	R	H	-0.4734
43	W	H	0.0000
44	Y	H	0.2095
45	R	H	0.0000
46	Q	H	-0.4511
47	A	H	-0.1021
48	P	H	-0.3372
49	G	H	-0.8117
50	K	H	-1.9991
51	Q	H	-1.6323
52	R	H	-1.1674
53	E	H	-1.1436
54	F	H	0.3550
55	V	H	0.0000
56	A	H	0.0000
57	G	H	0.0000
58	F	H	0.2073
59	T	H	0.1227
60	A	H	-0.1033
65	T	H	-0.1159
66	G	H	-0.5163
67	N	H	-1.3311
68	T	H	-0.4849
69	N	H	-1.2353
70	Y	H	0.0349
71	A	H	-0.2650
72	D	H	-1.8259
73	S	H	-0.5350
74	M	H	0.0000
75	K	H	-1.7840
76	G	H	-0.8287
77	R	H	-0.3992
78	F	H	0.0000
79	T	H	-0.0702
80	I	H	0.0000
81	S	H	-0.1675
82	R	H	-0.3201
83	D	H	-0.6168
84	N	H	-1.3478
85	T	H	-0.5986
86	K	H	-1.7879
87	N	H	-0.7256
88	A	H	0.0000
89	V	H	0.0000
90	Y	H	0.4388
91	L	H	0.0000
92	Q	H	-0.4552
93	I	H	0.0000
94	D	H	-0.8381
95	S	H	-0.3759
96	L	H	0.0000
97	K	H	-1.3623
98	P	H	-0.8106
99	E	H	-1.8649
100	D	H	0.0000
101	T	H	-0.0182
102	A	H	0.0000
103	V	H	0.3713
104	Y	H	0.0000
105	Y	H	0.1488
106	C	H	0.0000
107	Y	H	0.2624
108	M	H	0.0000
109	L	H	0.2829
137	D	H	-1.8726
138	K	H	-1.3310
139	W	H	0.3809
140	G	H	-0.1760
141	Q	H	-1.2291
142	G	H	-0.3021
143	T	H	-0.1976
144	Q	H	-0.8833
145	V	H	0.0000
146	T	H	0.1728
147	V	H	0.0000
148	S	H	-0.1753
149	S	H	-0.2380