Project name: Wei Li

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASGFTLSDYYMSWVRQAPGKGLEWMGIIYPGDSDTRYSPSFQGHVTISRDDSKNTLYLQMNSLRAEDTAVYYCTRWGAGKDVWGQGTTVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:52)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:53)

• Minimal score value: -2.5193
• Maximal score value: 1.2255
• Average score: -0.6969
• Total score value: -80.84

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-2.1200
2	V	C	-1.2529
3	Q	C	-1.2534
4	L	C	0.0000
5	V	C	1.0928
6	E	C	0.2694
7	S	C	-0.4211
8	G	C	-0.8617
9	G	C	-0.3791
10	G	C	0.3046
11	L	C	1.2255
12	V	C	0.0934
13	Q	C	-1.1888
14	P	C	-1.5157
15	G	C	-1.3144
16	G	C	-0.9498
17	S	C	-1.1840
18	L	C	-0.7376
19	R	C	-1.4865
20	L	C	0.0000
21	S	C	-0.2523
22	C	C	0.0000
23	A	C	-0.1765
24	A	C	0.0000
25	S	C	-0.8980
26	G	C	-1.2231
27	F	C	-0.7281
28	T	C	-0.7027
29	L	C	0.0000
30	S	C	-1.6410
31	D	C	-1.7988
32	Y	C	-0.4299
33	Y	C	-0.1088
34	M	C	0.0000
35	S	C	0.0000
36	W	C	0.0000
37	V	C	0.0000
38	R	C	0.0000
39	Q	C	-0.5385
40	A	C	-1.1847
41	P	C	-1.1302
42	G	C	-1.4155
43	K	C	-2.0735
44	G	C	-0.9011
45	L	C	0.5787
46	E	C	-0.1608
47	W	C	0.3053
48	M	C	0.0000
49	G	C	0.0000
50	I	C	0.0000
51	I	C	0.0000
52	Y	C	-1.1027
53	P	C	-1.2660
54	G	C	-1.7135
55	D	C	-1.9710
56	S	C	-1.6901
57	D	C	-2.5193
58	T	C	-1.8695
59	R	C	-2.2821
60	Y	C	-1.1646
61	S	C	-0.8260
62	P	C	-0.9144
63	S	C	-0.8386
64	F	C	0.0000
65	Q	C	-1.8420
66	G	C	-1.3621
67	H	C	-1.4239
68	V	C	0.0000
69	T	C	-0.9342
70	I	C	0.0000
71	S	C	-0.7451
72	R	C	0.0000
73	D	C	-1.9122
74	D	C	-2.3091
75	S	C	-1.7172
76	K	C	-2.5022
77	N	C	-1.9422
78	T	C	0.0000
79	L	C	0.0000
80	Y	C	-0.3962
81	L	C	0.0000
82	Q	C	-0.9988
83	M	C	0.0000
84	N	C	-1.5380
85	S	C	-1.2193
86	L	C	0.0000
87	R	C	-1.6093
88	A	C	-1.3655
89	E	C	-1.9759
90	D	C	0.0000
91	T	C	-0.5560
92	A	C	0.0000
93	V	C	0.0758
94	Y	C	0.0000
95	Y	C	0.2488
96	C	C	0.0000
97	T	C	0.0000
98	R	C	0.0000
99	W	C	-0.0212
100	G	C	-0.5345
101	A	C	-0.9072
102	G	C	-1.2787
103	K	C	-1.5747
104	D	C	-2.0581
105	V	C	-0.9984
106	W	C	-0.2056
107	G	C	-0.0728
108	Q	C	-0.8790
109	G	C	-0.3450
110	T	C	-0.2744
111	T	C	-0.1530
112	V	C	0.0000
113	T	C	0.0363
114	V	C	0.0000
115	S	C	-0.6307
116	S	C	-0.6018