Project name: clone54

Chain sequence(s)	H: EVQLLESGGSLVQPGGSLRLSCAASGFTFYTYTMNWVRQAPGKGLEWVATIYYDGSNKFYADSVKGRFTISRDNSMDTLHLQMNSLRAEDTAVYYCVSAGWLDNWGQGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCRTNQGISNDLGWYQQEPGKAPKRLIHSASDLESGVPSRFSGSASGTEFTLTISSLQPEDFATYYCLQYNDYPRTFGQGTKVEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:43)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:44)

• Minimal score value: -2.7218
• Maximal score value: 1.535
• Average score: -0.5737
• Total score value: -127.3539

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.8627
2	V	H	-0.9229
3	Q	H	-1.0591
4	L	H	0.0000
5	L	H	0.9100
6	E	H	0.0000
7	S	H	-0.1994
8	G	H	-0.5010
9	G	H	0.2518
11	S	H	0.7274
12	L	H	1.4177
13	V	H	-0.0367
14	Q	H	-1.3548
15	P	H	-1.6417
16	G	H	-1.4348
17	G	H	-1.1614
18	S	H	-1.1795
19	L	H	-0.8656
20	R	H	-1.9482
21	L	H	0.0000
22	S	H	-0.4732
23	C	H	0.0000
24	A	H	0.1739
25	A	H	0.0000
26	S	H	-0.7051
27	G	H	-0.9632
28	F	H	-0.0956
29	T	H	0.4190
30	F	H	0.0000
35	Y	H	1.0534
36	T	H	0.8713
37	Y	H	1.0279
38	T	H	0.0000
39	M	H	0.0000
40	N	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.6758
45	A	H	-1.0651
46	P	H	-0.8413
47	G	H	-1.5399
48	K	H	-2.3643
49	G	H	-1.6227
50	L	H	0.0000
51	E	H	-0.9914
52	W	H	0.0000
53	V	H	0.0000
54	A	H	0.0000
55	T	H	0.0000
56	I	H	0.0000
57	Y	H	-0.0049
58	Y	H	0.5771
59	D	H	-1.0351
62	G	H	-1.0431
63	S	H	-1.2282
64	N	H	-1.5793
65	K	H	-1.0595
66	F	H	-0.2714
67	Y	H	-0.6421
68	A	H	-1.4114
69	D	H	-2.6285
70	S	H	-1.7478
71	V	H	0.0000
72	K	H	-2.5189
74	G	H	-1.6926
75	R	H	-1.3778
76	F	H	0.0000
77	T	H	-0.8260
78	I	H	0.0000
79	S	H	-0.5618
80	R	H	-0.6981
81	D	H	-1.0953
82	N	H	-0.6802
83	S	H	-0.2408
84	M	H	0.2123
85	D	H	-0.4473
86	T	H	0.0000
87	L	H	0.0000
88	H	H	-0.8531
89	L	H	0.0000
90	Q	H	-1.0991
91	M	H	0.0000
92	N	H	-1.2423
93	S	H	-1.1974
94	L	H	0.0000
95	R	H	-2.3543
96	A	H	-1.7338
97	E	H	-2.2556
98	D	H	0.0000
99	T	H	-0.3947
100	A	H	0.0000
101	V	H	0.6240
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	V	H	0.0000
106	S	H	0.0000
107	A	H	0.0000
108	G	H	0.1752
114	W	H	0.2612
115	L	H	0.0000
116	D	H	-0.7707
117	N	H	-0.6860
118	W	H	-0.5181
119	G	H	0.0000
120	Q	H	-1.1399
121	G	H	-0.1673
122	T	H	0.5661
123	L	H	1.5350
124	V	H	0.0000
125	T	H	0.3160
126	V	H	0.0000
127	S	H	-0.5580
128	S	H	-0.5641
1	D	L	-2.5875
2	I	L	0.0000
3	Q	L	-2.3995
4	M	L	0.0000
5	T	L	-1.5023
6	Q	L	0.0000
7	S	L	-0.7741
8	P	L	-0.7231
9	S	L	-1.0339
10	S	L	-1.3351
11	L	L	-0.9234
12	S	L	-1.1112
13	A	L	0.0000
14	S	L	-0.1170
15	V	L	0.8690
16	G	L	-0.4164
17	D	L	-1.2761
18	R	L	-2.1410
19	V	L	0.0000
20	T	L	-0.5893
21	I	L	0.0000
22	T	L	-0.6901
23	C	L	0.0000
24	R	L	-2.7218
25	T	L	0.0000
26	N	L	-2.5256
27	Q	L	-2.5868
28	G	L	-1.9265
29	I	L	0.0000
36	S	L	-1.2102
37	N	L	-1.4259
38	D	L	-1.1363
39	L	L	0.0000
40	G	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	E	L	-1.5000
46	P	L	-1.0997
47	G	L	-1.6231
48	K	L	-2.4207
49	A	L	-1.5613
50	P	L	0.0000
51	K	L	-1.5165
52	R	L	-0.7845
53	L	L	0.0000
54	I	L	0.0000
55	H	L	-0.6021
56	S	L	-0.6963
57	A	L	0.0000
65	S	L	-0.8684
66	D	L	-0.9400
67	L	L	-0.2475
68	E	L	-0.6542
69	S	L	-0.5191
70	G	L	-0.4997
71	V	L	-0.3102
72	P	L	-0.3133
74	S	L	-0.4145
75	R	L	-0.7282
76	F	L	0.0000
77	S	L	-0.4524
78	G	L	-0.4409
79	S	L	-0.6988
80	A	L	-0.8711
83	S	L	-0.9281
84	G	L	-1.3257
85	T	L	-1.7629
86	E	L	-1.5864
87	F	L	0.0000
88	T	L	-0.5794
89	L	L	0.0000
90	T	L	-0.6412
91	I	L	0.0000
92	S	L	-1.3883
93	S	L	-1.0500
94	L	L	0.0000
95	Q	L	-0.7312
96	P	L	-0.6031
97	E	L	-1.8379
98	D	L	0.0000
99	F	L	-0.7472
100	A	L	0.0000
101	T	L	0.0000
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	L	L	0.0000
106	Q	L	0.0000
107	Y	L	-0.5015
108	N	L	-1.2794
109	D	L	-1.2937
114	Y	L	-0.2848
115	P	L	-0.8039
116	R	L	0.0000
117	T	L	-0.8564
118	F	L	-0.4567
119	G	L	0.0000
120	Q	L	-1.6041
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-2.2696
124	V	L	0.0000
125	E	L	-1.6834
126	I	L	0.5940
127	K	L	-0.9758