Project name: f6c3085272602d4

Chain sequence(s)	A: GVFTYESEFTSEIPPPRLFKAFVLDADNLVPKIAPQAIKHSEILWGDGGPGTIKKITFGEGSQYGYVKHKIDSIDKENYSYSYTLIEGDALGDTLEKISYETKLVASPSGGSIIKSTSHYHTKGNVEIKEEHVKAGKEKASNLFKLIETYLKGHPDAYN
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:27)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:28)

• Minimal score value: -4.395
• Maximal score value: 0.8027
• Average score: -1.2433
• Total score value: -197.6862

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-0.7608
2	V	A	0.3024
3	F	A	0.4103
4	T	A	0.0277
5	Y	A	-0.8852
6	E	A	-2.4957
7	S	A	-1.7433
8	E	A	-1.6510
9	F	A	0.8027
10	T	A	0.1361
11	S	A	0.0000
12	E	A	-2.3249
13	I	A	0.0000
14	P	A	-0.7878
15	P	A	0.0000
16	P	A	-1.0999
17	R	A	-0.8835
18	L	A	0.0000
19	F	A	0.0000
20	K	A	-0.8560
21	A	A	0.0000
22	F	A	-0.2270
23	V	A	0.0000
24	L	A	-0.3224
25	D	A	-0.9126
26	A	A	-0.9927
27	D	A	-2.2027
28	N	A	-2.6574
29	L	A	0.0000
30	V	A	0.0000
31	P	A	-2.3792
32	K	A	-2.5784
33	I	A	-0.7661
34	A	A	0.0000
35	P	A	-2.2727
36	Q	A	-2.3248
37	A	A	-1.6239
38	I	A	0.0000
39	K	A	-3.0474
40	H	A	-2.7221
41	S	A	-1.9874
42	E	A	-2.0507
43	I	A	-0.5016
44	L	A	0.5820
45	W	A	0.6014
46	G	A	-0.6924
47	D	A	-1.6604
48	G	A	-0.9647
49	G	A	-1.1078
50	P	A	-1.3890
51	G	A	-1.2435
52	T	A	0.0000
53	I	A	-0.2602
54	K	A	0.0000
55	K	A	-0.9181
56	I	A	-0.8650
57	T	A	-0.8672
58	F	A	-1.1405
59	G	A	-2.1405
60	E	A	-2.6631
61	G	A	-1.7653
62	S	A	-1.0693
63	Q	A	-1.1009
64	Y	A	0.2216
65	G	A	-0.5454
66	Y	A	-0.4031
67	V	A	0.0000
68	K	A	-0.5767
69	H	A	-0.4242
70	K	A	-0.9119
71	I	A	0.0000
72	D	A	-2.0841
73	S	A	-1.2140
74	I	A	-1.2973
75	D	A	-2.2193
76	K	A	-2.8955
77	E	A	-3.2454
78	N	A	-2.6178
79	Y	A	-1.7656
80	S	A	0.0000
81	Y	A	0.0000
82	S	A	-1.1992
83	Y	A	-1.0356
84	T	A	-1.1200
85	L	A	0.0000
86	I	A	-0.5721
87	E	A	-1.1825
88	G	A	-1.1325
89	D	A	-2.0773
90	A	A	-1.3984
91	L	A	0.0000
92	G	A	-2.0522
93	D	A	-2.5611
94	T	A	-2.1803
95	L	A	0.0000
96	E	A	-2.7267
97	K	A	-2.4065
98	I	A	0.0000
99	S	A	-0.8723
100	Y	A	-0.7167
101	E	A	-1.6356
102	T	A	0.0000
103	K	A	-1.6113
104	L	A	0.0000
105	V	A	0.3080
106	A	A	-0.0488
107	S	A	-0.3400
108	P	A	-0.4791
109	S	A	-0.8365
110	G	A	-1.0317
111	G	A	-1.0962
112	S	A	0.0000
113	I	A	0.1812
114	I	A	0.0000
115	K	A	-1.6305
116	S	A	-1.7272
117	T	A	-1.8134
118	S	A	-0.7414
119	H	A	-0.3960
120	Y	A	-0.7890
121	H	A	-1.8483
122	T	A	0.0000
123	K	A	-3.1434
124	G	A	-2.1537
125	N	A	-1.9720
126	V	A	-1.4491
127	E	A	-2.3353
128	I	A	-2.1954
129	K	A	-3.6909
130	E	A	-4.3950
131	E	A	-4.1072
132	H	A	-3.2567
133	V	A	0.0000
134	K	A	-4.2258
135	A	A	-3.4494
136	G	A	-3.0238
137	K	A	-3.5466
138	E	A	-3.6429
139	K	A	-3.2412
140	A	A	-1.9947
141	S	A	-1.8589
142	N	A	-1.9756
143	L	A	-1.0299
144	F	A	0.0000
145	K	A	-0.8103
146	L	A	-0.1400
147	I	A	0.0000
148	E	A	-1.4682
149	T	A	-1.2971
150	Y	A	-1.2540
151	L	A	0.0000
152	K	A	-2.7223
153	G	A	-1.9794
154	H	A	-2.3006
155	P	A	-2.2559
156	D	A	-2.7934
157	A	A	-1.9143
158	Y	A	-1.1712
159	N	A	-2.1016