| Chain sequence(s) |
A: MTIPSAEGFLHAASCLPCTAEEERDLVVALTREAEENVKDGDLRYLVSHSWWLNWQSYVGLIKPDENDADMLPQAPSRPGEIDNSKLVSEESSSIGDEPELQRTLREGDDYALVPQEVWRKLHEWYKGGPELSRRVICSSPTSRSYIVDVYPLRLKLFDGRDSLERIIRISRKAKVSELYSLVCSLLSVEQSKIDIWDFYQKTKGKKLINLNETVEEAQLMMDQEIIIEAKADDAWCSDLGTRSNNELALIPLEPSTSSFSIAGGPAFSNGFSSGFGSSFSQDNSFSPLLRDAEDGYSFSNGTKDDIHGLSGLHNLGNTCFMNSAIQSLVHTPPLVEYFLQDYSREINTENPLGLQGELATAFGELLRKLWSAGRTSIAPRPFKTKLSRFAPQFSGYNQHDSQELLAFLLDGLHEDLNRVKKKPYIEAKDADGRPDEELAEECWNYHKARNDSIIVDKFQGQYKSTLVCPDCKKISVTFDPFMYLSLPLPSTVTRMINVTVFSGTGDALPMPYTVKVQKNGVCGDLIKSLSVMCCLQSCETLLLAEVYDHRIYRYWNPSEPLCHVKDEDKLVAYRLPVGSENLLRVEILHRVVDRYTSESMFNLSRKLIGSPLVTCIPSDSTRKADIYATVSSLLAPFVRAKVHTLDESATKLNSNGPSLDGIVLTDNGVTCEEDVSTSNVDEEAADEEVLPFQLWLTDDKANKREHIDADSNGVPGSTMRLLMDWSDREHEVYDIKYMDELSVVFKPGFMSKKNRQEAVNLFSCLDAFLKDEPLGPDDMWYCPRCTEHKQASKKLDLWRLPEILVVHLKRFSYSRFMKNKLDTFVNFPIHDLDMSRYANHSRGDQPPIYELYAVINHYGGMGGGHYSAYAKLVEEDSWYHFDDSHVSSVGEEDIRTSSAYLLFYRRVGSSSCSVSKNVAVDTDMVDSLDT
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | RC495A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 2.39629 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:18:46)
[INFO] FoldX: Starting FoldX energy minimalization (00:19:10)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:28:29)
[INFO] Main: Simulation completed successfully. (00:28:47)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 1.4691 | |
| 2 | T | A | 1.3303 | |
| 3 | I | A | 2.0606 | |
| 4 | P | A | 0.5209 | |
| 5 | S | A | -0.3897 | |
| 6 | A | A | -0.5646 | |
| 7 | E | A | -1.4725 | |
| 8 | G | A | -0.1596 | |
| 9 | F | A | 1.8113 | |
| 10 | L | A | 1.6642 | |
| 11 | H | A | 0.2237 | |
| 12 | A | A | 0.2677 | |
| 13 | A | A | 0.3850 | |
| 14 | S | A | 0.4775 | |
| 15 | C | A | 1.3662 | |
| 16 | L | A | 1.7739 | |
| 17 | P | A | 0.7739 | |
| 18 | C | A | -0.1598 | |
| 19 | T | A | -1.0446 | |
| 20 | A | A | -1.9781 | |
| 21 | E | A | -3.1779 | |
| 22 | E | A | -3.1847 | |
| 23 | E | A | 0.0000 | |
| 24 | R | A | -2.0647 | |
| 25 | D | A | -2.6047 | |
| 26 | L | A | -1.2789 | |
| 27 | V | A | 0.0000 | |
| 28 | V | A | -0.8603 | |
| 29 | A | A | -1.2623 | |
| 30 | L | A | -1.8797 | |
| 31 | T | A | -2.2795 | |
| 32 | R | A | -3.7078 | |
| 33 | E | A | -4.0718 | |
| 34 | A | A | -3.4954 | |
| 35 | E | A | -4.2516 | |
| 36 | E | A | -4.3056 | |
| 37 | N | A | -3.3454 | |
| 38 | V | A | -2.6150 | |
| 39 | K | A | -3.4058 | |
| 40 | D | A | -2.8697 | |
| 41 | G | A | -1.8970 | |
| 42 | D | A | -1.6826 | |
| 43 | L | A | -0.9426 | |
| 44 | R | A | 0.0000 | |
| 45 | Y | A | 0.0000 | |
| 46 | L | A | 0.0000 | |
| 47 | V | A | 0.0000 | |
| 48 | S | A | 0.0000 | |
| 49 | H | A | -1.5756 | |
| 50 | S | A | -0.9379 | |
| 51 | W | A | 0.0000 | |
| 52 | W | A | -0.1791 | |
| 53 | L | A | 0.2092 | |
| 54 | N | A | -1.1944 | |
| 55 | W | A | 0.0000 | |
| 56 | Q | A | -0.0992 | |
| 57 | S | A | -0.4487 | |
| 58 | Y | A | -0.6395 | |
| 59 | V | A | 0.0000 | |
| 60 | G | A | -0.6884 | |
| 61 | L | A | 0.5057 | |
| 62 | I | A | 0.1310 | |
| 63 | K | A | -1.9681 | |
| 64 | P | A | -2.6427 | |
| 65 | D | A | -3.9023 | |
| 66 | E | A | -4.0980 | |
| 67 | N | A | -3.8488 | |
| 68 | D | A | -3.5311 | |
| 69 | A | A | -2.2346 | |
| 70 | D | A | -1.6613 | |
| 71 | M | A | 0.3165 | |
| 72 | L | A | 1.0198 | |
| 73 | P | A | -0.2829 | |
| 74 | Q | A | -0.8106 | |
| 75 | A | A | -0.6663 | |
| 76 | P | A | -1.1504 | |
| 77 | S | A | -1.1829 | |
| 78 | R | A | -1.5639 | |
| 79 | P | A | -1.4342 | |
| 80 | G | A | -2.2254 | |
| 81 | E | A | -3.1858 | |
| 82 | I | A | 0.0000 | |
| 83 | D | A | -2.9659 | |
| 84 | N | A | 0.0000 | |
| 85 | S | A | -1.7411 | |
| 86 | K | A | -2.1267 | |
| 87 | L | A | 0.0000 | |
| 88 | V | A | -1.5040 | |
| 89 | S | A | -2.2116 | |
| 90 | E | A | -3.0479 | |
| 91 | E | A | -2.8862 | |
| 92 | S | A | -1.8733 | |
| 93 | S | A | -1.0404 | |
| 94 | S | A | -0.2726 | |
| 95 | I | A | 1.0608 | |
| 96 | G | A | -0.5928 | |
| 97 | D | A | -1.9843 | |
| 98 | E | A | -1.7367 | |
| 99 | P | A | -1.8110 | |
| 100 | E | A | -1.6375 | |
| 101 | L | A | 0.0000 | |
| 102 | Q | A | -2.0355 | |
| 103 | R | A | -2.3662 | |
| 104 | T | A | -1.7072 | |
| 105 | L | A | -2.4967 | |
| 106 | R | A | -3.6568 | |
| 107 | E | A | -3.4579 | |
| 108 | G | A | -2.6576 | |
| 109 | D | A | -3.4062 | |
| 110 | D | A | -2.8804 | |
| 111 | Y | A | 0.0000 | |
| 112 | A | A | -1.1608 | |
| 113 | L | A | -0.0691 | |
| 114 | V | A | 0.0000 | |
| 115 | P | A | 0.0000 | |
| 116 | Q | A | -1.3761 | |
| 117 | E | A | -2.3923 | |
| 118 | V | A | 0.0000 | |
| 119 | W | A | 0.0000 | |
| 120 | R | A | -3.3672 | |
| 121 | K | A | -2.5497 | |
| 122 | L | A | 0.0000 | |
| 123 | H | A | -3.1131 | |
| 124 | E | A | -2.9895 | |
| 125 | W | A | -1.8721 | |
| 126 | Y | A | 0.0000 | |
| 127 | K | A | -3.3343 | |
| 128 | G | A | -2.6911 | |
| 129 | G | A | -1.9555 | |
| 130 | P | A | -1.5960 | |
| 131 | E | A | -1.8620 | |
| 132 | L | A | 0.0000 | |
| 133 | S | A | -0.7734 | |
| 134 | R | A | 0.0000 | |
| 135 | R | A | -1.8718 | |
| 136 | V | A | 0.0000 | |
| 137 | I | A | 0.0000 | |
| 138 | C | A | -1.1007 | |
| 139 | S | A | -0.3695 | |
| 140 | S | A | -0.7001 | |
| 141 | P | A | -0.9842 | |
| 142 | T | A | -0.8756 | |
| 143 | S | A | -1.2093 | |
| 144 | R | A | -2.3749 | |
| 145 | S | A | -0.8623 | |
| 146 | Y | A | -0.2233 | |
| 147 | I | A | 1.0031 | |
| 148 | V | A | 0.3360 | |
| 149 | D | A | 0.0000 | |
| 150 | V | A | 0.0000 | |
| 151 | Y | A | -0.3030 | |
| 152 | P | A | -0.3772 | |
| 153 | L | A | 0.0000 | |
| 154 | R | A | -0.6285 | |
| 155 | L | A | 0.0000 | |
| 156 | K | A | -0.8876 | |
| 157 | L | A | 0.0000 | |
| 158 | F | A | -0.5979 | |
| 159 | D | A | 0.0000 | |
| 160 | G | A | -1.7370 | |
| 161 | R | A | -2.6002 | |
| 162 | D | A | -2.1451 | |
| 163 | S | A | -1.1101 | |
| 164 | L | A | -0.2840 | |
| 165 | E | A | -1.1355 | |
| 166 | R | A | -0.3143 | |
| 167 | I | A | -0.2304 | |
| 168 | I | A | 0.0000 | |
| 169 | R | A | -0.4633 | |
| 170 | I | A | 0.0000 | |
| 171 | S | A | -1.2062 | |
| 172 | R | A | -1.5473 | |
| 173 | K | A | -1.5724 | |
| 174 | A | A | -1.7942 | |
| 175 | K | A | -2.5286 | |
| 176 | V | A | 0.0000 | |
| 177 | S | A | -1.3042 | |
| 178 | E | A | -1.8543 | |
| 179 | L | A | 0.0000 | |
| 180 | Y | A | 0.0000 | |
| 181 | S | A | -0.9556 | |
| 182 | L | A | -0.0267 | |
| 183 | V | A | 0.0000 | |
| 184 | C | A | -0.6474 | |
| 185 | S | A | 0.0649 | |
| 186 | L | A | 1.0458 | |
| 187 | L | A | 0.3913 | |
| 188 | S | A | -0.2268 | |
| 189 | V | A | -1.0792 | |
| 190 | E | A | -2.6365 | |
| 191 | Q | A | -2.2795 | |
| 192 | S | A | -2.0667 | |
| 193 | K | A | -3.0659 | |
| 194 | I | A | 0.0000 | |
| 195 | D | A | -0.8299 | |
| 196 | I | A | 0.0000 | |
| 197 | W | A | -0.5476 | |
| 198 | D | A | -1.1064 | |
| 199 | F | A | 0.0000 | |
| 200 | Y | A | -1.3491 | |
| 201 | Q | A | -2.1857 | |
| 202 | K | A | -2.5983 | |
| 203 | T | A | -1.9697 | |
| 204 | K | A | -2.4282 | |
| 205 | G | A | -1.9114 | |
| 206 | K | A | -1.4105 | |
| 207 | K | A | -0.7231 | |
| 208 | L | A | 0.0000 | |
| 209 | I | A | 1.2556 | |
| 210 | N | A | -0.4941 | |
| 211 | L | A | -0.6400 | |
| 212 | N | A | -1.8741 | |
| 213 | E | A | -1.8684 | |
| 214 | T | A | -2.4448 | |
| 215 | V | A | 0.0000 | |
| 216 | E | A | -2.6730 | |
| 217 | E | A | -3.1686 | |
| 218 | A | A | 0.0000 | |
| 219 | Q | A | -1.7707 | |
| 220 | L | A | 0.0000 | |
| 221 | M | A | -0.3974 | |
| 222 | M | A | -0.2948 | |
| 223 | D | A | -0.6828 | |
| 224 | Q | A | 0.0000 | |
| 225 | E | A | -1.1857 | |
| 226 | I | A | 0.0000 | |
| 227 | I | A | -0.7219 | |
| 228 | I | A | 0.0000 | |
| 229 | E | A | -1.4674 | |
| 230 | A | A | -1.9737 | |
| 231 | K | A | -2.6513 | |
| 232 | A | A | -2.1584 | |
| 233 | D | A | -2.9986 | |
| 234 | D | A | -2.3792 | |
| 235 | A | A | -0.5710 | |
| 236 | W | A | 0.6281 | |
| 237 | C | A | 0.7493 | |
| 238 | S | A | -0.1220 | |
| 239 | D | A | -0.9556 | |
| 240 | L | A | 0.2477 | |
| 241 | G | A | -0.7760 | |
| 242 | T | A | -1.2599 | |
| 243 | R | A | -2.3494 | |
| 244 | S | A | -2.2895 | |
| 245 | N | A | -2.7528 | |
| 246 | N | A | -2.6248 | |
| 247 | E | A | -1.8768 | |
| 248 | L | A | 0.8842 | |
| 249 | A | A | 1.3909 | |
| 250 | L | A | 2.8912 | |
| 251 | I | A | 2.9633 | |
| 252 | P | A | 1.3936 | |
| 253 | L | A | 1.1038 | |
| 254 | E | A | -1.0484 | |
| 255 | P | A | -0.9084 | |
| 256 | S | A | -0.6672 | |
| 257 | T | A | -0.3883 | |
| 258 | S | A | 0.1227 | |
| 259 | S | A | 0.6525 | |
| 260 | F | A | 1.9880 | |
| 261 | S | A | 1.4218 | |
| 262 | I | A | 2.0678 | |
| 263 | A | A | 0.7486 | |
| 264 | G | A | 0.1859 | |
| 265 | G | A | 0.0554 | |
| 266 | P | A | 0.2902 | |
| 267 | A | A | 0.6787 | |
| 268 | F | A | 1.3373 | |
| 269 | S | A | 0.0357 | |
| 270 | N | A | -0.7524 | |
| 271 | G | A | -0.1910 | |
| 272 | F | A | 1.1522 | |
| 273 | S | A | 0.4562 | |
| 274 | S | A | 0.3327 | |
| 275 | G | A | 0.4130 | |
| 276 | F | A | 1.3245 | |
| 277 | G | A | 0.4216 | |
| 278 | S | A | 0.3885 | |
| 279 | S | A | 0.5087 | |
| 280 | F | A | 1.0895 | |
| 281 | S | A | -0.5274 | |
| 282 | Q | A | -2.0353 | |
| 283 | D | A | -2.8963 | |
| 284 | N | A | -2.1944 | |
| 285 | S | A | -0.4405 | |
| 286 | F | A | 1.5700 | |
| 287 | S | A | 1.1718 | |
| 288 | P | A | 0.9840 | |
| 289 | L | A | 1.6984 | |
| 290 | L | A | 0.8422 | |
| 291 | R | A | -1.8509 | |
| 292 | D | A | -2.7914 | |
| 293 | A | A | -2.5028 | |
| 294 | E | A | -3.3662 | |
| 295 | D | A | -2.8073 | |
| 296 | G | A | -1.0287 | |
| 297 | Y | A | 0.7108 | |
| 298 | S | A | 0.8178 | |
| 299 | F | A | 1.5732 | |
| 300 | S | A | 0.0928 | |
| 301 | N | A | -1.3718 | |
| 302 | G | A | -1.8037 | |
| 303 | T | A | -2.0355 | |
| 304 | K | A | -2.8015 | |
| 305 | D | A | -2.6668 | |
| 306 | D | A | -1.8422 | |
| 307 | I | A | -0.2419 | |
| 308 | H | A | -0.6903 | |
| 309 | G | A | 0.0000 | |
| 310 | L | A | -0.2811 | |
| 311 | S | A | 0.0000 | |
| 312 | G | A | 0.0000 | |
| 313 | L | A | 0.0000 | |
| 314 | H | A | -1.1309 | |
| 315 | N | A | -0.9563 | |
| 316 | L | A | 0.0000 | |
| 317 | G | A | -0.9746 | |
| 318 | N | A | -1.5223 | |
| 319 | T | A | 0.0000 | |
| 320 | C | A | 0.0000 | |
| 321 | F | A | 0.0000 | |
| 322 | M | A | 0.0000 | |
| 323 | N | A | 0.0000 | |
| 324 | S | A | 0.0000 | |
| 325 | A | A | 0.0000 | |
| 326 | I | A | 0.0000 | |
| 327 | Q | A | 0.0000 | |
| 328 | S | A | 0.0000 | |
| 329 | L | A | 0.0000 | |
| 330 | V | A | 0.0000 | |
| 331 | H | A | 0.0000 | |
| 332 | T | A | 0.0000 | |
| 333 | P | A | -0.6870 | |
| 334 | P | A | 0.0000 | |
| 335 | L | A | 0.0000 | |
| 336 | V | A | 0.0000 | |
| 337 | E | A | -1.8926 | |
| 338 | Y | A | -1.1389 | |
| 339 | F | A | 0.0000 | |
| 340 | L | A | -0.8197 | |
| 341 | Q | A | -2.0514 | |
| 342 | D | A | -2.7334 | |
| 343 | Y | A | 0.0000 | |
| 344 | S | A | -1.6772 | |
| 345 | R | A | -2.2433 | |
| 346 | E | A | 0.0000 | |
| 347 | I | A | -0.8053 | |
| 348 | N | A | 0.0000 | |
| 349 | T | A | -1.4878 | |
| 350 | E | A | -2.4954 | |
| 351 | N | A | 0.0000 | |
| 352 | P | A | -0.5672 | |
| 353 | L | A | 0.8816 | |
| 354 | G | A | -0.1558 | |
| 355 | L | A | -0.6493 | |
| 356 | Q | A | -1.4312 | |
| 357 | G | A | 0.0000 | |
| 358 | E | A | -0.6923 | |
| 359 | L | A | 0.0000 | |
| 360 | A | A | 0.0000 | |
| 361 | T | A | -0.8051 | |
| 362 | A | A | -0.9908 | |
| 363 | F | A | 0.0000 | |
| 364 | G | A | 0.0000 | |
| 365 | E | A | -2.3218 | |
| 366 | L | A | 0.0000 | |
| 367 | L | A | 0.0000 | |
| 368 | R | A | -1.8379 | |
| 369 | K | A | -2.1387 | |
| 370 | L | A | 0.0000 | |
| 371 | W | A | -0.3861 | |
| 372 | S | A | -0.7976 | |
| 373 | A | A | -0.9583 | |
| 374 | G | A | -1.4968 | |
| 375 | R | A | -1.8662 | |
| 376 | T | A | -1.0162 | |
| 377 | S | A | -0.7127 | |
| 378 | I | A | 0.0000 | |
| 379 | A | A | -0.5659 | |
| 380 | P | A | 0.0000 | |
| 381 | R | A | -1.1507 | |
| 382 | P | A | -1.0386 | |
| 383 | F | A | 0.0000 | |
| 384 | K | A | 0.0000 | |
| 385 | T | A | -1.1225 | |
| 386 | K | A | -1.4333 | |
| 387 | L | A | 0.0000 | |
| 388 | S | A | -1.3964 | |
| 389 | R | A | -2.1370 | |
| 390 | F | A | -0.9195 | |
| 391 | A | A | 0.0000 | |
| 392 | P | A | -1.3346 | |
| 393 | Q | A | -1.9527 | |
| 394 | F | A | 0.0000 | |
| 395 | S | A | -1.2844 | |
| 396 | G | A | -1.2900 | |
| 397 | Y | A | -1.4343 | |
| 398 | N | A | -2.3811 | |
| 399 | Q | A | -2.0502 | |
| 400 | H | A | -1.7084 | |
| 401 | D | A | -1.3237 | |
| 402 | S | A | 0.0000 | |
| 403 | Q | A | -1.2458 | |
| 404 | E | A | -1.9670 | |
| 405 | L | A | 0.0000 | |
| 406 | L | A | 0.0000 | |
| 407 | A | A | -0.6648 | |
| 408 | F | A | -0.4058 | |
| 409 | L | A | 0.0000 | |
| 410 | L | A | 0.0000 | |
| 411 | D | A | -0.6576 | |
| 412 | G | A | 0.0000 | |
| 413 | L | A | 0.0000 | |
| 414 | H | A | 0.0000 | |
| 415 | E | A | -0.4647 | |
| 416 | D | A | 0.0000 | |
| 417 | L | A | 0.0000 | |
| 418 | N | A | 0.0000 | |
| 419 | R | A | -1.6006 | |
| 420 | V | A | -1.8727 | |
| 421 | K | A | -3.2250 | |
| 422 | K | A | -2.8910 | |
| 423 | K | A | -1.4780 | |
| 424 | P | A | -0.3103 | |
| 425 | Y | A | 0.8296 | |
| 426 | I | A | 0.0492 | |
| 427 | E | A | -1.7635 | |
| 428 | A | A | -1.5565 | |
| 429 | K | A | -2.9834 | |
| 430 | D | A | -2.9089 | |
| 431 | A | A | -2.3424 | |
| 432 | D | A | -2.6612 | |
| 433 | G | A | -1.7383 | |
| 434 | R | A | -2.3970 | |
| 435 | P | A | -2.5038 | |
| 436 | D | A | -3.0978 | |
| 437 | E | A | -3.8587 | |
| 438 | E | A | -3.6324 | |
| 439 | L | A | 0.0000 | |
| 440 | A | A | 0.0000 | |
| 441 | E | A | -2.5772 | |
| 442 | E | A | -1.8978 | |
| 443 | C | A | -1.3297 | |
| 444 | W | A | -1.2460 | |
| 445 | N | A | -1.4681 | |
| 446 | Y | A | -0.4058 | |
| 447 | H | A | -1.0254 | |
| 448 | K | A | -1.6116 | |
| 449 | A | A | -0.9699 | |
| 450 | R | A | -1.6021 | |
| 451 | N | A | -1.6911 | |
| 452 | D | A | -1.5937 | |
| 453 | S | A | 0.0000 | |
| 454 | I | A | 0.0000 | |
| 455 | I | A | 0.0000 | |
| 456 | V | A | 0.0000 | |
| 457 | D | A | -1.7556 | |
| 458 | K | A | -1.3654 | |
| 459 | F | A | 0.0000 | |
| 460 | Q | A | -0.6184 | |
| 461 | G | A | 0.0000 | |
| 462 | Q | A | 0.0000 | |
| 463 | Y | A | -0.5064 | |
| 464 | K | A | -0.7220 | |
| 465 | S | A | 0.0000 | |
| 466 | T | A | -0.0210 | |
| 467 | L | A | -0.1318 | |
| 468 | V | A | -0.2275 | |
| 469 | C | A | 0.0000 | |
| 470 | P | A | -1.5214 | |
| 471 | D | A | -2.6037 | |
| 472 | C | A | -1.7490 | |
| 473 | K | A | -1.9917 | |
| 474 | K | A | -0.7790 | |
| 475 | I | A | 0.9292 | |
| 476 | S | A | 0.1240 | |
| 477 | V | A | -0.2287 | |
| 478 | T | A | -0.7057 | |
| 479 | F | A | 0.0000 | |
| 480 | D | A | -0.7085 | |
| 481 | P | A | -0.2464 | |
| 482 | F | A | 0.0000 | |
| 483 | M | A | -0.0167 | |
| 484 | Y | A | 0.1747 | |
| 485 | L | A | 0.0000 | |
| 486 | S | A | -0.4071 | |
| 487 | L | A | 0.0000 | |
| 488 | P | A | -0.6330 | |
| 489 | L | A | 0.0000 | |
| 490 | P | A | -0.2670 | |
| 491 | S | A | 0.2859 | |
| 492 | T | A | 0.1769 | |
| 493 | V | A | 0.8083 | |
| 494 | T | A | -0.2539 | |
| 495 | C | A | -0.0854 | mutated: RC495A |
| 496 | M | A | 0.0769 | |
| 497 | I | A | 0.0000 | |
| 498 | N | A | -0.2537 | |
| 499 | V | A | 0.0000 | |
| 500 | T | A | 0.0000 | |
| 501 | V | A | 0.0000 | |
| 502 | F | A | 0.0000 | |
| 503 | S | A | -0.4117 | |
| 504 | G | A | 0.0000 | |
| 505 | T | A | -0.7153 | |
| 506 | G | A | -0.9389 | |
| 507 | D | A | -1.7371 | |
| 508 | A | A | -0.4983 | |
| 509 | L | A | 0.5845 | |
| 510 | P | A | 0.4876 | |
| 511 | M | A | 1.1269 | |
| 512 | P | A | 0.0678 | |
| 513 | Y | A | 0.4438 | |
| 514 | T | A | -0.0028 | |
| 515 | V | A | 0.0000 | |
| 516 | K | A | -1.5842 | |
| 517 | V | A | 0.0000 | |
| 518 | Q | A | -1.2933 | |
| 519 | K | A | -0.9808 | |
| 520 | N | A | -1.2323 | |
| 521 | G | A | -0.8035 | |
| 522 | V | A | -0.4432 | |
| 523 | C | A | 0.0000 | |
| 524 | G | A | 0.0000 | |
| 525 | D | A | -1.5534 | |
| 526 | L | A | 0.0000 | |
| 527 | I | A | -0.4364 | |
| 528 | K | A | -1.3780 | |
| 529 | S | A | -0.6066 | |
| 530 | L | A | 0.0000 | |
| 531 | S | A | 0.3842 | |
| 532 | V | A | 1.8361 | |
| 533 | M | A | 1.5580 | |
| 534 | C | A | 0.0000 | |
| 535 | C | A | 1.3288 | |
| 536 | L | A | 0.2879 | |
| 537 | Q | A | -0.5495 | |
| 538 | S | A | -0.1637 | |
| 539 | C | A | 0.5673 | |
| 540 | E | A | -0.0060 | |
| 541 | T | A | 0.0365 | |
| 542 | L | A | 0.0000 | |
| 543 | L | A | -0.1138 | |
| 544 | L | A | 0.0000 | |
| 545 | A | A | 0.0000 | |
| 546 | E | A | 0.0000 | |
| 547 | V | A | 0.0000 | |
| 548 | Y | A | 0.3988 | |
| 549 | D | A | -1.4559 | |
| 550 | H | A | -1.2672 | |
| 551 | R | A | -0.7196 | |
| 552 | I | A | 0.2547 | |
| 553 | Y | A | 0.9047 | |
| 554 | R | A | 0.1400 | |
| 555 | Y | A | -0.0725 | |
| 556 | W | A | 0.0000 | |
| 557 | N | A | -1.4337 | |
| 558 | P | A | -1.0730 | |
| 559 | S | A | -0.7813 | |
| 560 | E | A | -0.7087 | |
| 561 | P | A | -0.6373 | |
| 562 | L | A | 0.0000 | |
| 563 | C | A | -0.3580 | |
| 564 | H | A | -0.8119 | |
| 565 | V | A | -1.0422 | |
| 566 | K | A | -1.4347 | |
| 567 | D | A | -1.8944 | |
| 568 | E | A | -2.5311 | |
| 569 | D | A | -1.3221 | |
| 570 | K | A | -0.8445 | |
| 571 | L | A | 0.0000 | |
| 572 | V | A | 0.0000 | |
| 573 | A | A | 0.0000 | |
| 574 | Y | A | 0.0000 | |
| 575 | R | A | -0.3158 | |
| 576 | L | A | 0.0000 | |
| 577 | P | A | 0.2096 | |
| 578 | V | A | 0.9718 | |
| 579 | G | A | -0.3569 | |
| 580 | S | A | 0.0000 | |
| 581 | E | A | -2.1714 | |
| 582 | N | A | -1.9687 | |
| 583 | L | A | -1.2324 | |
| 584 | L | A | 0.0000 | |
| 585 | R | A | -0.8969 | |
| 586 | V | A | 0.0000 | |
| 587 | E | A | 0.0000 | |
| 588 | I | A | 0.0000 | |
| 589 | L | A | 0.0000 | |
| 590 | H | A | 0.0000 | |
| 591 | R | A | -0.4248 | |
| 592 | V | A | -0.3693 | |
| 593 | V | A | -0.6892 | |
| 594 | D | A | -1.7589 | |
| 595 | R | A | -1.9572 | |
| 596 | Y | A | -0.1403 | |
| 597 | T | A | -0.2570 | |
| 598 | S | A | -0.7982 | |
| 599 | E | A | -1.4404 | |
| 600 | S | A | -0.5016 | |
| 601 | M | A | 0.6941 | |
| 602 | F | A | 0.3668 | |
| 603 | N | A | -0.4704 | |
| 604 | L | A | 0.8347 | |
| 605 | S | A | -0.3950 | |
| 606 | R | A | -1.8525 | |
| 607 | K | A | -2.2078 | |
| 608 | L | A | -1.3513 | |
| 609 | I | A | -1.1377 | |
| 610 | G | A | 0.0000 | |
| 611 | S | A | 0.0000 | |
| 612 | P | A | 0.0000 | |
| 613 | L | A | 0.0000 | |
| 614 | V | A | 0.0000 | |
| 615 | T | A | 0.0000 | |
| 616 | C | A | -0.4361 | |
| 617 | I | A | 0.0000 | |
| 618 | P | A | -1.1453 | |
| 619 | S | A | -1.4899 | |
| 620 | D | A | -2.5838 | |
| 621 | S | A | -2.0240 | |
| 622 | T | A | -2.6413 | |
| 623 | R | A | -3.7005 | |
| 624 | K | A | -2.6059 | |
| 625 | A | A | -1.3147 | |
| 626 | D | A | -2.1928 | |
| 627 | I | A | 0.0000 | |
| 628 | Y | A | 0.0000 | |
| 629 | A | A | -0.5254 | |
| 630 | T | A | -0.3836 | |
| 631 | V | A | 0.0000 | |
| 632 | S | A | -0.2951 | |
| 633 | S | A | -0.4591 | |
| 634 | L | A | 0.0000 | |
| 635 | L | A | 0.0000 | |
| 636 | A | A | -0.0747 | |
| 637 | P | A | -0.1454 | |
| 638 | F | A | 0.0000 | |
| 639 | V | A | 0.3576 | |
| 640 | R | A | -0.7212 | |
| 641 | A | A | -0.4862 | |
| 642 | K | A | -1.1050 | |
| 643 | V | A | 0.5609 | |
| 644 | H | A | -0.4760 | |
| 645 | T | A | -0.2813 | |
| 646 | L | A | 0.0506 | |
| 647 | D | A | -2.1436 | |
| 648 | E | A | -2.3494 | |
| 649 | S | A | -1.5214 | |
| 650 | A | A | -0.7997 | |
| 651 | T | A | -0.9820 | |
| 652 | K | A | -1.3183 | |
| 653 | L | A | -0.1201 | |
| 654 | N | A | -1.3552 | |
| 655 | S | A | -1.4784 | |
| 656 | N | A | -1.7817 | |
| 657 | G | A | -1.1643 | |
| 658 | P | A | -0.7975 | |
| 659 | S | A | -0.0898 | |
| 660 | L | A | 0.5635 | |
| 661 | D | A | -0.6731 | |
| 662 | G | A | 0.6769 | |
| 663 | I | A | 2.8233 | |
| 664 | V | A | 2.9470 | |
| 665 | L | A | 2.2457 | |
| 666 | T | A | 0.1502 | |
| 667 | D | A | -1.9603 | |
| 668 | N | A | -1.8241 | |
| 669 | G | A | -0.5989 | |
| 670 | V | A | 1.4012 | |
| 671 | T | A | 0.4324 | |
| 672 | C | A | -0.1848 | |
| 673 | E | A | -2.6514 | |
| 674 | E | A | -3.0801 | |
| 675 | D | A | -2.3190 | |
| 676 | V | A | 0.1541 | |
| 677 | S | A | -0.2043 | |
| 678 | T | A | -0.1570 | |
| 679 | S | A | -0.4975 | |
| 680 | N | A | -1.2221 | |
| 681 | V | A | -0.5725 | |
| 682 | D | A | -2.5555 | |
| 683 | E | A | -3.1600 | |
| 684 | E | A | -3.0771 | |
| 685 | A | A | -2.2667 | |
| 686 | A | A | -2.3000 | |
| 687 | D | A | -3.1431 | |
| 688 | E | A | -2.9606 | |
| 689 | E | A | -2.2587 | |
| 690 | V | A | 0.2805 | |
| 691 | L | A | 0.3572 | |
| 692 | P | A | -0.0890 | |
| 693 | F | A | 0.0000 | |
| 694 | Q | A | -0.5867 | |
| 695 | L | A | 0.0000 | |
| 696 | W | A | -1.2166 | |
| 697 | L | A | -1.6133 | |
| 698 | T | A | -2.3424 | |
| 699 | D | A | -2.6492 | |
| 700 | D | A | -2.7837 | |
| 701 | K | A | -3.2209 | |
| 702 | A | A | 0.0000 | |
| 703 | N | A | -3.1641 | |
| 704 | K | A | -3.4215 | |
| 705 | R | A | -2.7056 | |
| 706 | E | A | -3.1891 | |
| 707 | H | A | -2.5691 | |
| 708 | I | A | 0.0000 | |
| 709 | D | A | -3.5306 | |
| 710 | A | A | -2.7085 | |
| 711 | D | A | -3.3178 | |
| 712 | S | A | -2.6223 | |
| 713 | N | A | -2.5358 | |
| 714 | G | A | -1.4474 | |
| 715 | V | A | -0.1791 | |
| 716 | P | A | -0.4584 | |
| 717 | G | A | -0.5934 | |
| 718 | S | A | -0.8516 | |
| 719 | T | A | -0.3507 | |
| 720 | M | A | 0.0000 | |
| 721 | R | A | -0.8577 | |
| 722 | L | A | 0.0000 | |
| 723 | L | A | 0.0000 | |
| 724 | M | A | 0.0000 | |
| 725 | D | A | 0.0000 | |
| 726 | W | A | 0.0000 | |
| 727 | S | A | -2.0565 | |
| 728 | D | A | -3.2071 | |
| 729 | R | A | -3.1271 | |
| 730 | E | A | 0.0000 | |
| 731 | H | A | -2.0266 | |
| 732 | E | A | -2.6611 | |
| 733 | V | A | -1.0534 | |
| 734 | Y | A | -0.4724 | |
| 735 | D | A | -0.7563 | |
| 736 | I | A | 0.0000 | |
| 737 | K | A | -2.2230 | |
| 738 | Y | A | -0.6358 | |
| 739 | M | A | 0.0000 | |
| 740 | D | A | -2.5714 | |
| 741 | E | A | -2.6305 | |
| 742 | L | A | 0.0000 | |
| 743 | S | A | -1.0509 | |
| 744 | V | A | -1.1544 | |
| 745 | V | A | 0.0000 | |
| 746 | F | A | -0.3112 | |
| 747 | K | A | -1.3459 | |
| 748 | P | A | -0.6107 | |
| 749 | G | A | 0.2840 | |
| 750 | F | A | 1.4621 | |
| 751 | M | A | 0.4947 | |
| 752 | S | A | -0.6440 | |
| 753 | K | A | -2.6527 | |
| 754 | K | A | -3.4822 | |
| 755 | N | A | -3.8389 | |
| 756 | R | A | -4.0115 | |
| 757 | Q | A | -3.3409 | |
| 758 | E | A | -2.8577 | |
| 759 | A | A | -1.6435 | |
| 760 | V | A | 0.0000 | |
| 761 | N | A | -1.3964 | |
| 762 | L | A | 0.0000 | |
| 763 | F | A | -0.4480 | |
| 764 | S | A | -0.7054 | |
| 765 | C | A | 0.0000 | |
| 766 | L | A | 0.0000 | |
| 767 | D | A | -1.7739 | |
| 768 | A | A | -1.4565 | |
| 769 | F | A | -1.1472 | |
| 770 | L | A | -1.8329 | |
| 771 | K | A | -3.4572 | |
| 772 | D | A | -3.9146 | |
| 773 | E | A | -3.4432 | |
| 774 | P | A | -2.0242 | |
| 775 | L | A | -1.8099 | |
| 776 | G | A | -1.7687 | |
| 777 | P | A | -1.8938 | |
| 778 | D | A | -2.7139 | |
| 779 | D | A | -2.6404 | |
| 780 | M | A | -1.5151 | |
| 781 | W | A | -0.6210 | |
| 782 | Y | A | -0.3741 | |
| 783 | C | A | 0.0000 | |
| 784 | P | A | -1.2422 | |
| 785 | R | A | -2.4090 | |
| 786 | C | A | -1.8883 | |
| 787 | T | A | -1.4621 | |
| 788 | E | A | -2.1559 | |
| 789 | H | A | -1.7044 | |
| 790 | K | A | -1.6622 | |
| 791 | Q | A | -1.5944 | |
| 792 | A | A | 0.0000 | |
| 793 | S | A | -1.4596 | |
| 794 | K | A | -1.9891 | |
| 795 | K | A | -2.2905 | |
| 796 | L | A | -1.2167 | |
| 797 | D | A | -0.9414 | |
| 798 | L | A | 0.0000 | |
| 799 | W | A | 0.0000 | |
| 800 | R | A | -0.7694 | |
| 801 | L | A | -0.5019 | |
| 802 | P | A | 0.0000 | |
| 803 | E | A | -1.5444 | |
| 804 | I | A | 0.0000 | |
| 805 | L | A | 0.0000 | |
| 806 | V | A | 0.0000 | |
| 807 | V | A | 0.0000 | |
| 808 | H | A | 0.0000 | |
| 809 | L | A | 0.0000 | |
| 810 | K | A | -1.1941 | |
| 811 | R | A | 0.0000 | |
| 812 | F | A | -0.7965 | |
| 813 | S | A | -0.4681 | |
| 814 | Y | A | 0.3147 | |
| 815 | S | A | -0.2875 | |
| 816 | R | A | -0.8397 | |
| 817 | F | A | 0.9560 | |
| 818 | M | A | -0.1956 | |
| 819 | K | A | -1.6595 | |
| 820 | N | A | -1.9397 | |
| 821 | K | A | -1.4358 | |
| 822 | L | A | -1.0696 | |
| 823 | D | A | -1.8248 | |
| 824 | T | A | 0.0000 | |
| 825 | F | A | -1.1276 | |
| 826 | V | A | 0.0000 | |
| 827 | N | A | -1.0505 | |
| 828 | F | A | 0.0000 | |
| 829 | P | A | -1.2215 | |
| 830 | I | A | 0.0000 | |
| 831 | H | A | -1.7281 | |
| 832 | D | A | -2.3569 | |
| 833 | L | A | 0.0000 | |
| 834 | D | A | -1.7804 | |
| 835 | M | A | 0.0000 | |
| 836 | S | A | -1.6230 | |
| 837 | R | A | -2.2174 | |
| 838 | Y | A | -1.3744 | |
| 839 | A | A | -1.3472 | |
| 840 | N | A | -2.4645 | |
| 841 | H | A | -2.5772 | |
| 842 | S | A | -2.4138 | |
| 843 | R | A | -3.0559 | |
| 844 | G | A | -2.6324 | |
| 845 | D | A | -3.3965 | |
| 846 | Q | A | -2.6053 | |
| 847 | P | A | -1.6818 | |
| 848 | P | A | 0.0000 | |
| 849 | I | A | -1.1288 | |
| 850 | Y | A | 0.0000 | |
| 851 | E | A | -1.5254 | |
| 852 | L | A | 0.0000 | |
| 853 | Y | A | 0.0000 | |
| 854 | A | A | 0.0000 | |
| 855 | V | A | 0.0000 | |
| 856 | I | A | 0.0000 | |
| 857 | N | A | 0.0000 | |
| 858 | H | A | 0.0000 | |
| 859 | Y | A | -0.4757 | |
| 860 | G | A | -0.9788 | |
| 861 | G | A | -1.2660 | |
| 862 | M | A | -0.9337 | |
| 863 | G | A | -1.1197 | |
| 864 | G | A | -1.0404 | |
| 865 | G | A | -1.1538 | |
| 866 | H | A | -1.3263 | |
| 867 | Y | A | 0.0000 | |
| 868 | S | A | 0.0000 | |
| 869 | A | A | 0.0000 | |
| 870 | Y | A | 0.0000 | |
| 871 | A | A | 0.0000 | |
| 872 | K | A | 0.0000 | |
| 873 | L | A | 0.0000 | |
| 874 | V | A | -1.4327 | |
| 875 | E | A | -2.7355 | |
| 876 | E | A | -2.8459 | |
| 877 | D | A | -2.7718 | |
| 878 | S | A | -1.6414 | |
| 879 | W | A | 0.0000 | |
| 880 | Y | A | 0.0142 | |
| 881 | H | A | -0.1701 | |
| 882 | F | A | 0.0000 | |
| 883 | D | A | -0.7071 | |
| 884 | D | A | -0.8599 | |
| 885 | S | A | -1.1167 | |
| 886 | H | A | -0.9944 | |
| 887 | V | A | -0.2983 | |
| 888 | S | A | -0.0724 | |
| 889 | S | A | -0.1367 | |
| 890 | V | A | -0.7020 | |
| 891 | G | A | -1.5327 | |
| 892 | E | A | -2.2209 | |
| 893 | E | A | -3.0953 | |
| 894 | D | A | -2.8539 | |
| 895 | I | A | 0.0000 | |
| 896 | R | A | -2.0105 | |
| 897 | T | A | -1.2440 | |
| 898 | S | A | -0.6193 | |
| 899 | S | A | -0.4426 | |
| 900 | A | A | 0.0000 | |
| 901 | Y | A | 0.0000 | |
| 902 | L | A | 0.0000 | |
| 903 | L | A | 0.0000 | |
| 904 | F | A | 0.0000 | |
| 905 | Y | A | 0.0000 | |
| 906 | R | A | -1.1498 | |
| 907 | R | A | -1.3819 | |
| 908 | V | A | -0.5881 | |
| 909 | G | A | -0.7004 | |
| 910 | S | A | -0.5568 | |
| 911 | S | A | -0.0715 | |
| 912 | S | A | 0.2997 | |
| 913 | C | A | 0.6457 | |
| 914 | S | A | 0.2639 | |
| 915 | V | A | 1.0248 | |
| 916 | S | A | -0.1488 | |
| 917 | K | A | -1.4329 | |
| 918 | N | A | -0.7350 | |
| 919 | V | A | 0.9518 | |
| 920 | A | A | 0.6046 | |
| 921 | V | A | 1.0141 | |
| 922 | D | A | -1.0696 | |
| 923 | T | A | -0.8242 | |
| 924 | D | A | -1.4495 | |
| 925 | M | A | 0.3404 | |
| 926 | V | A | 1.1520 | |
| 927 | D | A | -0.8853 | |
| 928 | S | A | -0.1628 | |
| 929 | L | A | 0.3846 | |
| 930 | D | A | -1.3706 | |
| 931 | T | A | -0.5495 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine