Project name: fb16cc627db167

Chain sequence(s)	C: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMAWFRQAPGKGRELVAAISSSGGYTYYADSVKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAARSGGLTKESAFDESKYDYWGQGTQVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:52)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:52)

• Minimal score value: -2.7185
• Maximal score value: 0.8791
• Average score: -0.804
• Total score value: -102.1129

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	C	-2.1379
2	V	C	-1.4700
3	Q	C	-1.3696
4	L	C	0.0000
5	V	C	0.6623
6	E	C	0.0000
7	S	C	-0.5677
8	G	C	-1.1538
9	G	C	-0.8686
10	G	C	-0.0860
11	L	C	0.8791
12	V	C	0.0000
13	Q	C	-1.4123
14	P	C	-1.6276
15	G	C	-1.3743
16	G	C	-1.0095
17	S	C	-1.3417
18	L	C	-1.1511
19	R	C	-2.1854
20	L	C	0.0000
21	S	C	-0.4350
22	C	C	0.0000
23	A	C	-0.3010
24	A	C	0.0000
25	S	C	-1.0943
26	G	C	-1.2417
27	F	C	-0.6008
28	T	C	-0.3127
29	F	C	0.0000
30	S	C	-0.6701
31	S	C	-0.4694
32	Y	C	-0.5106
33	A	C	0.0000
34	M	C	0.0000
35	A	C	0.0000
36	W	C	0.0000
37	F	C	0.0000
38	R	C	0.0000
39	Q	C	-1.7172
40	A	C	-1.7114
41	P	C	-1.1512
42	G	C	-1.6612
43	K	C	-2.7185
44	G	C	-2.3020
45	R	C	-2.4242
46	E	C	-2.0151
47	L	C	0.0000
48	V	C	0.0000
49	A	C	0.0000
50	A	C	0.0000
51	I	C	0.0000
52	S	C	-0.1081
53	S	C	-0.4778
54	S	C	-0.4854
55	G	C	-0.3449
56	G	C	-0.0303
57	Y	C	0.7560
58	T	C	0.2467
59	Y	C	0.0000
60	Y	C	-1.0128
61	A	C	-1.4613
62	D	C	-2.4779
63	S	C	-1.7193
64	V	C	0.0000
65	K	C	-2.6106
66	G	C	-1.7413
67	R	C	-1.5021
68	F	C	0.0000
69	T	C	-0.8566
70	I	C	0.0000
71	S	C	-0.2627
72	R	C	-1.0365
73	D	C	-1.5149
74	N	C	-1.7334
75	A	C	-1.4485
76	K	C	-2.3927
77	R	C	-2.0507
78	M	C	-1.0220
79	V	C	0.0000
80	Y	C	-0.5121
81	L	C	0.0000
82	Q	C	-1.2344
83	M	C	0.0000
84	N	C	-1.4639
85	S	C	-1.1899
86	L	C	0.0000
87	R	C	-2.2503
88	A	C	-1.7111
89	E	C	-2.2221
90	D	C	0.0000
91	T	C	-0.8391
92	A	C	0.0000
93	V	C	-0.3842
94	Y	C	0.0000
95	Y	C	-0.2555
96	C	C	0.0000
97	A	C	0.0000
98	A	C	0.0000
99	R	C	-1.3138
100	S	C	-1.0624
101	G	C	-0.8996
102	G	C	-0.7872
103	L	C	0.0000
104	T	C	-1.2891
105	K	C	-2.2111
106	E	C	-2.3572
107	S	C	-1.7330
108	A	C	0.0000
109	F	C	-0.5631
110	D	C	-1.5381
111	E	C	-1.7343
112	S	C	-1.4920
113	K	C	-2.0445
114	Y	C	0.0000
115	D	C	-1.9741
116	Y	C	-0.7144
117	W	C	-0.2472
118	G	C	-0.2277
119	Q	C	-1.0630
120	G	C	-0.5058
121	T	C	-0.7112
122	Q	C	-1.0695
123	V	C	0.0000
124	T	C	-0.3294
125	V	C	0.0000
126	S	C	-0.8131
127	S	C	-0.5319