Project name: 183

Chain sequence(s)	H: QVQLQESGGDSVEAGGSLRLSCAASGSTYSSNCMGWFRQAPGKEREEVASMSIRSGNAYYSDSVKGRFTISHDGSKNTLYLQMNSLKAEDTAMYYCAAAYGGSRCDYNYRGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:44)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:45)

• Minimal score value: -2.9953
• Maximal score value: 1.1398
• Average score: -0.9499
• Total score value: -113.9899

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.8146
2	V	H	0.0000
3	Q	H	-2.2161
4	L	H	0.0000
5	Q	H	-2.0015
6	E	H	0.0000
7	S	H	-1.1287
8	G	H	-1.3787
9	G	H	-1.6389
11	D	H	-2.3147
12	S	H	-1.5131
13	V	H	-1.4920
14	E	H	-2.1733
15	A	H	-1.7832
16	G	H	-1.4190
17	G	H	0.0000
18	S	H	-1.1036
19	L	H	-1.2212
20	R	H	-1.5521
21	L	H	0.0000
22	S	H	-0.6318
23	C	H	0.0000
24	A	H	-1.1559
25	A	H	0.0000
26	S	H	-1.3639
27	G	H	-1.0746
28	S	H	-0.5572
29	T	H	-0.0614
30	Y	H	1.1398
35	S	H	0.4026
36	S	H	-0.1265
37	N	H	0.0000
38	C	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	-0.4777
43	R	H	0.0000
44	Q	H	-1.6029
45	A	H	-1.4909
46	P	H	-1.1117
47	G	H	-1.5592
48	K	H	-2.4588
49	E	H	-2.9953
50	R	H	-2.3455
51	E	H	-1.7810
52	E	H	-0.9057
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	M	H	0.0000
57	S	H	-0.7161
58	I	H	-0.9877
59	R	H	-2.0626
62	S	H	-1.4446
63	G	H	-1.3586
64	N	H	-1.0400
65	A	H	0.2031
66	Y	H	0.7497
67	Y	H	-0.2907
68	S	H	-1.2230
69	D	H	-2.3986
70	S	H	-1.7932
71	V	H	0.0000
72	K	H	-2.3941
74	G	H	-1.7176
75	R	H	-1.4779
76	F	H	0.0000
77	T	H	-0.5488
78	I	H	0.0000
79	S	H	-0.3714
80	H	H	-0.8062
81	D	H	-1.3516
82	G	H	-1.6792
83	S	H	-1.5272
84	K	H	-2.3351
85	N	H	-1.5442
86	T	H	-1.2480
87	L	H	0.0000
88	Y	H	-0.2811
89	L	H	0.0000
90	Q	H	-0.8487
91	M	H	0.0000
92	N	H	-1.1643
93	S	H	-1.2096
94	L	H	0.0000
95	K	H	-2.0502
96	A	H	-1.5170
97	E	H	-1.8255
98	D	H	0.0000
99	T	H	-1.0430
100	A	H	0.0000
101	M	H	-0.2878
102	Y	H	0.0000
103	Y	H	-0.9249
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	A	H	0.0000
108	Y	H	-0.2073
109	G	H	-1.2929
110	G	H	-1.2086
111	S	H	-1.5468
112	R	H	-2.5627
113	C	H	-1.8423
114	D	H	-2.6023
115	Y	H	-1.8249
116	N	H	-2.0414
117	Y	H	-2.0972
118	R	H	-2.5914
119	G	H	0.0000
120	Q	H	-1.8250
121	G	H	-1.1849
122	T	H	-1.0738
123	Q	H	-1.1716
124	V	H	0.0000
125	T	H	-1.2684
126	V	H	0.0000
127	S	H	-1.2750
128	S	H	-0.9494