Project name: fff097d09ab679d

Chain sequence(s)	A: MQVQLVESGGGSVQAGGSLRLSCTASGTKELKYAAFDLGWFRQAPGQEREAVAAIDRDGGITYYADSVKGRFTISRDNAKNTVTLQMNNLKPVDTAIYYCAARRSRNRTYESWGQGTQVTVSGGGGSHHHHHHLESRLEEELRRRLTE
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:52)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:53)

• Minimal score value: -3.6353
• Maximal score value: 1.2207
• Average score: -1.138
• Total score value: -168.4171

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.0279
2	Q	A	-1.3878
3	V	A	-1.2583
4	Q	A	-1.3615
5	L	A	0.0000
6	V	A	0.4847
7	E	A	0.0000
8	S	A	-0.6248
9	G	A	-1.2381
10	G	A	-1.1860
11	G	A	-0.9389
12	S	A	-0.6946
13	V	A	-0.8159
14	Q	A	-1.9230
15	A	A	-1.7276
16	G	A	-1.9560
17	G	A	-1.4166
18	S	A	-1.5245
19	L	A	-1.2695
20	R	A	-2.2148
21	L	A	0.0000
22	S	A	-0.5944
23	C	A	0.0000
24	T	A	-0.3785
25	A	A	0.0000
26	S	A	-0.8736
27	G	A	-0.9582
28	T	A	-0.7337
29	K	A	-1.2750
30	E	A	0.0000
31	L	A	-0.1178
32	K	A	-1.5424
33	Y	A	0.0000
34	A	A	-1.5745
35	A	A	-1.5358
36	F	A	-1.6691
37	D	A	0.0000
38	L	A	0.0000
39	G	A	0.0000
40	W	A	0.0000
41	F	A	-0.2350
42	R	A	0.0000
43	Q	A	-1.9890
44	A	A	-1.2166
45	P	A	-1.1977
46	G	A	-1.6779
47	Q	A	-2.7380
48	E	A	-3.5929
49	R	A	-3.1495
50	E	A	-2.2138
51	A	A	-0.8023
52	V	A	0.0000
53	A	A	0.0000
54	A	A	0.6127
55	I	A	0.0000
56	D	A	0.0000
57	R	A	-2.3674
58	D	A	-2.6363
59	G	A	-1.5343
60	G	A	-0.5529
61	I	A	1.1491
62	T	A	1.1438
63	Y	A	1.2207
64	Y	A	-0.2483
65	A	A	-1.0898
66	D	A	-2.3681
67	S	A	-1.3870
68	V	A	0.0000
69	K	A	-2.4570
70	G	A	-1.8917
71	R	A	-1.8369
72	F	A	0.0000
73	T	A	-0.7728
74	I	A	0.0000
75	S	A	-0.4801
76	R	A	-1.6851
77	D	A	-2.0654
78	N	A	-2.6535
79	A	A	-1.4077
80	K	A	-2.1701
81	N	A	-1.5585
82	T	A	-1.0910
83	V	A	0.0000
84	T	A	-0.7879
85	L	A	0.0000
86	Q	A	-1.3690
87	M	A	0.0000
88	N	A	-1.9773
89	N	A	-2.3505
90	L	A	0.0000
91	K	A	-1.5628
92	P	A	-0.4460
93	V	A	1.1687
94	D	A	0.0000
95	T	A	0.0642
96	A	A	0.0000
97	I	A	-0.3586
98	Y	A	0.0000
99	Y	A	-0.1540
100	C	A	0.0000
101	A	A	0.0000
102	A	A	0.0000
103	R	A	-2.2846
104	R	A	-3.0191
105	S	A	-2.2836
106	R	A	-2.8925
107	N	A	-2.8989
108	R	A	-2.6702
109	T	A	-1.8040
110	Y	A	-1.5323
111	E	A	-2.3957
112	S	A	-1.3761
113	W	A	-0.3298
114	G	A	-0.3172
115	Q	A	-1.0450
116	G	A	0.0000
117	T	A	0.0000
118	Q	A	-1.3402
119	V	A	0.0000
120	T	A	-0.5296
121	V	A	0.0000
122	S	A	-1.1788
123	G	A	-1.5696
124	G	A	-1.7034
125	G	A	-1.2956
126	G	A	-1.4681
127	S	A	-1.5787
128	H	A	-2.3376
129	H	A	-2.4965
130	H	A	-2.4495
131	H	A	-2.3644
132	H	A	-1.9672
133	H	A	-1.8150
134	L	A	-0.2520
135	E	A	-1.6722
136	S	A	-2.1358
137	R	A	-2.3256
138	L	A	-0.6238
139	E	A	-2.4935
140	E	A	-3.6353
141	E	A	-2.8756
142	L	A	-1.5220
143	R	A	-2.7321
144	R	A	-3.6025
145	R	A	-2.9534
146	L	A	-1.4026
147	T	A	-1.7925
148	E	A	-2.4632