a server for prediction of aggregation propensity in protein structures and rational design of protein solubility. In dynamic mode, A3D takes into account the flexibility of natural and designed polypeptides.
Aggrescan3D standalone version is currently in a beta stage. Visit our repository
To try it out! The standalone extends the functionality with dynamic mode supporting multichanin proteins and proteins longer than 400 AA, local server with extra functionality and more.
New Aggrescan3D server featuring all the standalone functionality and new interface is under construction and coming soon.
Papers describing Aggrescan3D server and its example applications: