CABS-fold server

CABS-fold

Server for de novo and consensus-based prediction of protein structure.
 

CABS-fold uses an efficient simulation procedure for protein structure prediction: in de novo fashion (from amino acid sequence only), guided by user-provided template(s) (consensus modeling) and/or user-provided distance restraints (e.g. from sparse experimental data). The web server output is a coarse grained trajectory of generated conformations, its Jmol representation and predicted models in all-atom resolution (together with accompanying analysis). Typically, the output is generated within 2-12 hours.

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Consensus modeling
De-novo modeling
Dear Users, note that the numbering of the residues should correspond to the query sequence order.
Thus the template(s), have to be already aligned to the query sequence.
You will get wrong results if your template is not aligned.

Format: 

A 3 14 7.8 10.12
D 55,58,120-160

"A" - add distance constraint (above example: distance range between 3 and 14 residue must be between 7.8 and 10.12). Constraint generated from templates for these residues will be deleted.
"D" - delete distance constaints (above example: remove all constraints between residues 55,58,120-160 and the rest of chain)
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- required field
When you publish results using the server, please cite the following papers describing the server and the method:

© Laboratory of Theory of Biopolymers 2013