Project name: MUT9

Status: done

Started: 2026-08-16 07:41:14
Chain sequence(s) A: QCISPGTGYNNGYFYSYWNDGRGGVTYCNGPGGQFSVNWSNSGNFVGGKGWQPGTKNKVINFSGSYNPNGNSYLSVYGWTRNPLIEYYIVENFGTYNPSTGATKLGEVTSDGSVYDIYQTTRVNQPSIIGTATFYQYWSVRRNHRSSGTVNTANHFNAWAALGLTLGTMDYQIVAVEGYFSSGSADITVS
input PDB
Selected Chain(s) A
Distance of aggregation 10 Å
FoldX usage Yes
pH calculations No
alphaCutter usage No
Dynamic mode No
Automated mutations No
Downloads Download all the data
Simulation log 
[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimization                                          (00:00:02)
[INFO]       Analysis: Starting Aggrescan4D on folded.pdb                                          (00:02:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:32)
Show buried residues
Minimal score value
-2.4651
Maximal score value
1.9228
Average score
-0.4335
Total score value
-82.3582
Download the table (csv)

The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan4D score mutation
1 Q A -0.7998
2 C A 0.2946
3 I A 0.2494
4 S A 0.0314
5 P A -0.2647
6 G A -0.2750
7 T A 0.0772
8 G A 0.3784
9 Y A 0.7642
10 N A -0.5795
11 N A -1.4550
12 G A -0.7720
13 Y A -0.2450
14 F A 0.0000
15 Y A 0.1948
16 S A 0.1835
17 Y A 0.0000
18 W A -0.0117
19 N A -0.9126
20 D A -1.5220
21 G A -1.8455
22 R A -2.4651
23 G A -1.8148
24 G A -1.3751
25 V A -1.0485
26 T A -0.3298
27 Y A 0.0000
28 C A -0.1962
29 N A 0.0000
30 G A -0.8953
31 P A -1.0648
32 G A -1.1034
33 G A 0.0000
34 Q A -0.9182
35 F A 0.0000
36 S A -0.8184
37 V A 0.0000
38 N A -1.6411
39 W A 0.0000
40 S A -1.1657
41 N A -1.2512
42 S A 0.0000
43 G A 0.0000
44 N A -0.1666
45 F A 0.0000
46 V A 0.1911
47 G A 0.0000
48 G A 0.0000
49 K A 0.0000
50 G A 0.0000
51 W A -0.0644
52 Q A -0.4709
53 P A -0.5614
54 G A 0.0000
55 T A -1.0768
56 K A -1.8644
57 N A -2.0905
58 K A -1.1500
59 V A -0.2316
60 I A 0.0000
61 N A -0.8558
62 F A 0.0000
63 S A -0.7479
64 G A -0.7497
65 S A -0.9475
66 Y A -1.0921
67 N A -1.8964
68 P A -1.6237
69 N A -1.7445
70 G A -0.6073
71 N A 0.1069
72 S A 0.0000
73 Y A 0.0000
74 L A 0.0000
75 S A 0.0000
76 V A 0.0000
77 Y A 0.0000
78 G A 0.0000
79 W A 0.0000
80 T A 0.0000
81 R A -1.2716
82 N A -1.7886
83 P A -1.0484
84 L A -0.1986
85 I A 0.0000
86 E A 0.0000
87 Y A 0.0000
88 Y A 0.0000
89 I A 0.0000
90 V A 0.0000
91 E A 0.0000
92 N A -1.0304
93 F A -0.3940
94 G A -0.6101
95 T A -0.2401
96 Y A 0.4102
97 N A -0.2542
98 P A 0.0000
99 S A -0.5630
100 T A -0.4585
101 G A -0.7256
102 A A -0.6197
103 T A -0.7420
104 K A -1.5085
105 L A -0.4308
106 G A -0.9250
107 E A -1.7319
108 V A -0.8684
109 T A -0.4700
110 S A 0.0000
111 D A -0.8786
112 G A -0.8463
113 S A 0.0000
114 V A -0.7600
115 Y A 0.0000
116 D A -1.2586
117 I A 0.0000
118 Y A 0.0000
119 Q A -0.3116
120 T A -0.0858
121 T A -0.0549
122 R A -0.5234
123 V A 0.5282
124 N A -1.0454
125 Q A -1.0518
126 P A -0.4566
127 S A 0.2370
128 I A 1.1830
129 I A 1.9228
130 G A 0.4326
131 T A -0.2440
132 A A -0.1249
133 T A -0.1203
134 F A 0.0000
135 Y A 0.7458
136 Q A 0.0000
137 Y A 0.0000
138 W A 0.0000
139 S A 0.0000
140 V A 0.0000
141 R A 0.0000
142 R A -2.3562
143 N A -2.4361
144 H A -1.8915
145 R A -1.2502
146 S A -0.7643
147 S A -0.6551
148 G A -0.6814
149 T A -0.5389
150 V A 0.0000
151 N A -0.8640
152 T A 0.0000
153 A A -1.4980
154 N A -1.2974
155 H A 0.0000
156 F A 0.0000
157 N A -1.5911
158 A A -0.8893
159 W A 0.0000
160 A A -0.2967
161 A A -0.0695
162 L A 0.2837
163 G A -0.1485
164 L A 0.0000
165 T A -0.3128
166 L A -0.5619
167 G A -0.8158
168 T A -0.8274
169 M A -0.6598
170 D A 0.0000
171 Y A 0.0000
172 Q A 0.0000
173 I A 0.0000
174 V A 0.0000
175 A A 0.0000
176 V A 0.0000
177 E A 0.0157
178 G A 0.0000
179 Y A 1.4091
180 F A 1.4293
181 S A 0.0000
182 S A -1.0675
183 G A -1.5948
184 S A -1.4607
185 A A 0.0000
186 D A -1.3561
187 I A 0.0000
188 T A -0.7532
189 V A 0.0000
190 S A -0.4354
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