Project name: 614a0b54d0f92b2

Chain sequence(s)	A: MAGLINKIGDALHIGGGNKEGEHKKEEEHKKHVDEHKSGEHKEGIVDKIKDKIHGGEGKSHDGEGKSHDGEKKKKKDKKEKKHHDDGHHSSSSDSDSD
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	No
pH calculations	No
alphaCutter usage	No
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:01)
[INFO]       Analysis: Starting Aggrescan4D on folded.pdb                                          (00:00:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:01)

• Minimal score value: -4.9728
• Maximal score value: 1.997
• Average score: -2.5469
• Total score value: -249.5958

The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan4D score	mutation
1	M	A	1.4769
2	A	A	0.8337
3	G	A	0.6926
4	L	A	1.9970
5	I	A	1.9704
6	N	A	-0.4334
7	K	A	-0.8485
8	I	A	1.6813
9	G	A	0.4330
10	D	A	-1.4109
11	A	A	-0.0348
12	L	A	1.2828
13	H	A	-0.1939
14	I	A	1.4089
15	G	A	-0.4366
16	G	A	-1.2355
17	G	A	-1.8677
18	N	A	-3.0758
19	K	A	-3.7712
20	E	A	-3.8663
21	G	A	-3.4381
22	E	A	-4.0476
23	H	A	-3.8942
24	K	A	-4.4738
25	K	A	-4.8028
26	E	A	-4.7827
27	E	A	-4.7873
28	E	A	-4.5373
29	H	A	-3.8706
30	K	A	-3.7461
31	K	A	-3.2303
32	H	A	-2.2565
33	V	A	-0.8911
34	D	A	-2.8118
35	E	A	-3.3469
36	H	A	-3.3551
37	K	A	-3.8403
38	S	A	-2.8690
39	G	A	-3.0032
40	E	A	-3.9082
41	H	A	-3.1993
42	K	A	-3.1245
43	E	A	-3.2066
44	G	A	-2.0347
45	I	A	-0.5857
46	V	A	-0.4632
47	D	A	-2.6615
48	K	A	-2.3414
49	I	A	-0.3697
50	K	A	-2.4639
51	D	A	-3.4988
52	K	A	-2.5370
53	I	A	-0.6023
54	H	A	-2.1716
55	G	A	-2.8493
56	G	A	-2.1389
57	E	A	-2.9574
58	G	A	-2.6770
59	K	A	-2.9080
60	S	A	-2.3305
61	H	A	-2.8731
62	D	A	-3.3050
63	G	A	-2.9298
64	E	A	-3.3452
65	G	A	-2.8254
66	K	A	-3.1513
67	S	A	-2.5841
68	H	A	-2.9012
69	D	A	-3.4503
70	G	A	-3.2960
71	E	A	-4.1119
72	K	A	-4.4911
73	K	A	-4.4908
74	K	A	-4.8549
75	K	A	-4.7517
76	K	A	-4.8492
77	D	A	-4.9728
78	K	A	-4.9471
79	K	A	-4.9021
80	E	A	-4.8021
81	K	A	-4.5605
82	K	A	-4.1983
83	H	A	-3.7013
84	H	A	-3.5249
85	D	A	-3.9927
86	D	A	-3.7105
87	G	A	-2.9380
88	H	A	-2.6148
89	H	A	-2.0823
90	S	A	-1.2977
91	S	A	-1.2136
92	S	A	-1.2426
93	S	A	-1.6340
94	D	A	-2.6854
95	S	A	-2.3332
96	D	A	-3.0186
97	S	A	-2.2541
98	D	A	-2.3460