| Chain sequence(s) |
A: LNGTLMQYFEWYMPNDGQHWKRLQNDSAYLAEHGITAVWIPPAYKGTSQADVGYGAYDLYDLGEFHQKGTVRTKYGTKGELQSAIKSLHSRDINVYGDVVINHKGGADATEDVTAVEVDPADRNRVISGEHLIKAWTHFHFPGRGSTYSDFKWHWYHFDGTDWDESRKLNRIYKFQGKAWDWEVSNEFGNYDYLMYADIDYDHPDVAAEIKRWGTWYANELQLDGFRLDAVKHIKFSFLRDWVNHVREKTGKEMFTVAEYWSYDLGALENYLNKTNFNHSVFDVPLHYQFHAASTQGGGYDMRKLLNGTVVSKHPLKSVTFVDNHDTQPGQSLESTVQTWFKPLAYAFILTRESGYPQVFYGDMYGTKGDSQREIPALKHKIEPILKARKQYAYGAQHDYFDHHDIVGWTREGDSSVANSGLAALITDGPGGAKRMYVGRQNAGETWHDITGNRSEPVVINSAGWGEFHVNGGSVSIYVQR
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| pH calculations | Yes |
| alphaCutter usage | No |
| Dynamic mode | No |
| Automated mutations | No |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] PDB-Info: The input structure is globular. Max score is recommended for pH analysis. (00:00:02)
[INFO] FoldX: Starting FoldX energy minimization (00:00:02)
[INFO] Analysis: Starting Aggrescan4D on folded.pdb (00:05:21)
[INFO] agg3D: Running pKa-ANI on
/STORAGE/DATA/lcbio/aggreskan/79404e10219562a/tmp/folded.pdb (00:05:21)
[INFO] Main: Simulation completed successfully. (00:07:57)
|
The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan4D score | mutation |
|---|---|---|---|---|
| 3 | L | A | 1.2076 | |
| 4 | N | A | -0.0583 | |
| 5 | G | A | 0.0911 | |
| 6 | T | A | 0.0000 | |
| 7 | L | A | 0.0000 | |
| 8 | M | A | 0.0000 | |
| 9 | Q | A | 0.0000 | |
| 10 | Y | A | 0.0000 | |
| 11 | F | A | 0.0000 | |
| 12 | E | A | 0.0000 | |
| 13 | W | A | 0.1927 | |
| 14 | Y | A | -0.2058 | |
| 15 | M | A | 0.0000 | |
| 16 | P | A | -0.8791 | |
| 17 | N | A | -1.1982 | |
| 18 | D | A | -1.3975 | |
| 19 | G | A | 0.0000 | |
| 20 | Q | A | -1.6988 | |
| 21 | H | A | 0.0000 | |
| 22 | W | A | 0.0000 | |
| 23 | K | A | -2.5303 | |
| 24 | R | A | -2.2189 | |
| 25 | L | A | 0.0000 | |
| 26 | Q | A | -2.2459 | |
| 27 | N | A | -2.2061 | |
| 28 | D | A | -1.2980 | |
| 29 | S | A | 0.0000 | |
| 30 | A | A | -1.1322 | |
| 31 | Y | A | -0.5739 | |
| 32 | L | A | 0.0000 | |
| 33 | A | A | -1.4101 | |
| 34 | E | A | -1.9319 | |
| 35 | H | A | 0.0000 | |
| 36 | G | A | -0.7170 | |
| 37 | I | A | 0.0000 | |
| 38 | T | A | -0.7886 | |
| 39 | A | A | 0.0000 | |
| 40 | V | A | 0.0000 | |
| 41 | W | A | 0.0000 | |
| 42 | I | A | 0.0000 | |
| 43 | P | A | 0.0000 | |
| 44 | P | A | 0.0000 | |
| 45 | A | A | 0.0000 | |
| 46 | Y | A | 0.0000 | |
| 47 | K | A | 0.0000 | |
| 48 | G | A | 0.0000 | |
| 49 | T | A | -0.6037 | |
| 50 | S | A | -0.8773 | |
| 51 | Q | A | -0.9304 | |
| 52 | A | A | -0.5439 | |
| 53 | D | A | -0.3885 | |
| 54 | V | A | 0.0829 | |
| 55 | G | A | 0.0000 | |
| 56 | Y | A | 0.0844 | |
| 57 | G | A | 0.0000 | |
| 58 | A | A | 0.0000 | |
| 59 | Y | A | 0.0000 | |
| 60 | D | A | 0.0000 | |
| 61 | L | A | 0.0000 | |
| 62 | Y | A | 0.0000 | |
| 63 | D | A | 0.0000 | |
| 64 | L | A | 0.0000 | |
| 65 | G | A | 0.0000 | |
| 66 | E | A | -0.4766 | |
| 67 | F | A | -0.4177 | |
| 68 | H | A | -1.0217 | |
| 69 | Q | A | 0.0000 | |
| 70 | K | A | -1.6468 | |
| 71 | G | A | -1.1635 | |
| 72 | T | A | 0.0000 | |
| 73 | V | A | 0.0994 | |
| 74 | R | A | -0.5232 | |
| 75 | T | A | 0.0000 | |
| 76 | K | A | 0.0000 | |
| 77 | Y | A | 0.0000 | |
| 78 | G | A | 0.0000 | |
| 79 | T | A | -0.5436 | |
| 80 | K | A | 0.0000 | |
| 81 | G | A | -0.9467 | |
| 82 | E | A | -1.5104 | |
| 83 | L | A | 0.0000 | |
| 84 | Q | A | -1.5307 | |
| 85 | S | A | -1.6150 | |
| 86 | A | A | 0.0000 | |
| 87 | I | A | 0.0000 | |
| 88 | K | A | -2.7566 | |
| 89 | S | A | -2.0807 | |
| 90 | L | A | 0.0000 | |
| 91 | H | A | -2.5897 | |
| 92 | S | A | -2.0215 | |
| 93 | R | A | -2.7366 | |
| 94 | D | A | -2.9150 | |
| 95 | I | A | 0.0000 | |
| 96 | N | A | -1.5382 | |
| 97 | V | A | 0.0000 | |
| 98 | Y | A | 0.0000 | |
| 99 | G | A | 0.0000 | |
| 100 | D | A | 0.0000 | |
| 101 | V | A | 0.0000 | |
| 102 | V | A | 0.0000 | |
| 103 | I | A | 0.0000 | |
| 104 | N | A | -0.4323 | |
| 105 | H | A | 0.0014 | |
| 106 | K | A | 0.0000 | |
| 107 | G | A | 0.0000 | |
| 108 | G | A | -0.3778 | |
| 109 | A | A | -0.4250 | |
| 110 | D | A | -1.0684 | |
| 111 | A | A | -0.7047 | |
| 112 | T | A | -0.9770 | |
| 113 | E | A | -1.5484 | |
| 114 | D | A | -1.9345 | |
| 115 | V | A | 0.0000 | |
| 116 | T | A | -0.7192 | |
| 117 | A | A | 0.0000 | |
| 118 | V | A | -0.4571 | |
| 119 | E | A | 0.0000 | |
| 120 | V | A | 0.0000 | |
| 121 | D | A | -0.5761 | |
| 122 | P | A | -0.2783 | |
| 123 | A | A | -0.5182 | |
| 124 | D | A | -1.0236 | |
| 125 | R | A | -0.8780 | |
| 126 | N | A | -1.1423 | |
| 127 | R | A | -1.2759 | |
| 128 | V | A | 0.8737 | |
| 129 | I | A | 1.3067 | |
| 130 | S | A | 0.2388 | |
| 131 | G | A | -0.6723 | |
| 132 | E | A | -1.8164 | |
| 133 | H | A | -0.5354 | |
| 134 | L | A | 0.3414 | |
| 135 | I | A | 0.0000 | |
| 136 | K | A | -1.9850 | |
| 137 | A | A | 0.0000 | |
| 138 | W | A | -0.2763 | |
| 139 | T | A | 0.0000 | |
| 140 | H | A | -0.8478 | |
| 141 | F | A | 0.0000 | |
| 142 | H | A | -1.7770 | |
| 143 | F | A | -1.1861 | |
| 144 | P | A | -1.0408 | |
| 145 | G | A | -0.9786 | |
| 146 | R | A | 0.0000 | |
| 147 | G | A | -0.9099 | |
| 148 | S | A | -1.3438 | |
| 149 | T | A | -0.3879 | |
| 150 | Y | A | -0.0005 | |
| 151 | S | A | -1.0727 | |
| 152 | D | A | -2.2767 | |
| 153 | F | A | -1.8800 | |
| 154 | K | A | -2.3012 | |
| 155 | W | A | 0.0000 | |
| 156 | H | A | -0.2344 | |
| 157 | W | A | 0.4414 | |
| 158 | Y | A | 1.1176 | |
| 159 | H | A | 0.0000 | |
| 160 | F | A | 0.0000 | |
| 161 | D | A | -0.3446 | |
| 162 | G | A | 0.0000 | |
| 163 | T | A | 0.0000 | |
| 164 | D | A | 0.0349 | |
| 165 | W | A | -0.6420 | |
| 166 | D | A | 0.0000 | |
| 167 | E | A | -1.4179 | |
| 168 | S | A | -1.1421 | |
| 169 | R | A | -1.7385 | |
| 170 | K | A | -2.0122 | |
| 171 | L | A | -0.4485 | |
| 172 | N | A | -1.1036 | |
| 173 | R | A | -1.1051 | |
| 174 | I | A | 0.0000 | |
| 175 | Y | A | 0.0000 | |
| 176 | K | A | 0.0000 | |
| 177 | F | A | 0.0000 | |
| 178 | Q | A | -1.5069 | |
| 179 | G | A | -1.4594 | |
| 180 | K | A | -1.4423 | |
| 181 | A | A | -0.9612 | |
| 182 | W | A | -0.9239 | |
| 183 | D | A | -1.8678 | |
| 184 | W | A | -0.6798 | |
| 185 | E | A | -1.5719 | |
| 186 | V | A | -1.3533 | |
| 187 | S | A | -1.3441 | |
| 188 | N | A | -1.9239 | |
| 189 | E | A | -1.7889 | |
| 190 | F | A | -0.3136 | |
| 191 | G | A | 0.0000 | |
| 192 | N | A | 0.0000 | |
| 193 | Y | A | 0.3158 | |
| 194 | D | A | -0.9465 | |
| 195 | Y | A | 0.6889 | |
| 196 | L | A | 1.4425 | |
| 197 | M | A | 0.9542 | |
| 198 | Y | A | 0.9262 | |
| 199 | A | A | 0.0000 | |
| 200 | D | A | 0.0000 | |
| 201 | I | A | -0.0184 | |
| 202 | D | A | -0.6158 | |
| 203 | Y | A | -1.4129 | |
| 204 | D | A | -2.3185 | |
| 205 | H | A | -1.5096 | |
| 206 | P | A | -1.7185 | |
| 207 | D | A | -2.2341 | |
| 208 | V | A | 0.0000 | |
| 209 | A | A | -1.3160 | |
| 210 | A | A | -1.1713 | |
| 211 | E | A | -1.3232 | |
| 212 | I | A | 0.0000 | |
| 213 | K | A | -1.2513 | |
| 214 | R | A | -1.4008 | |
| 215 | W | A | 0.0000 | |
| 216 | G | A | 0.0000 | |
| 217 | T | A | 0.0000 | |
| 218 | W | A | -1.0056 | |
| 219 | Y | A | 0.0000 | |
| 220 | A | A | 0.0000 | |
| 221 | N | A | -1.8629 | |
| 222 | E | A | -1.4497 | |
| 223 | L | A | 0.0000 | |
| 224 | Q | A | -2.1748 | |
| 225 | L | A | 0.0000 | |
| 226 | D | A | -1.2254 | |
| 227 | G | A | 0.0000 | |
| 228 | F | A | 0.0000 | |
| 229 | R | A | 0.0000 | |
| 230 | L | A | 0.0000 | |
| 231 | D | A | -0.7458 | |
| 232 | A | A | -1.0620 | |
| 233 | V | A | 0.0000 | |
| 234 | K | A | -1.9772 | |
| 235 | H | A | -1.5087 | |
| 236 | I | A | 0.0000 | |
| 237 | K | A | -1.9496 | |
| 238 | F | A | -0.6525 | |
| 239 | S | A | -0.6930 | |
| 240 | F | A | -1.0767 | |
| 241 | L | A | 0.0000 | |
| 242 | R | A | -1.7481 | |
| 243 | D | A | -1.8223 | |
| 244 | W | A | 0.0000 | |
| 245 | V | A | 0.0000 | |
| 246 | N | A | -2.6271 | |
| 247 | H | A | -2.4724 | |
| 248 | V | A | 0.0000 | |
| 249 | R | A | -3.2963 | |
| 250 | E | A | -3.6647 | |
| 251 | K | A | -3.3538 | |
| 252 | T | A | -2.6972 | |
| 253 | G | A | -2.4633 | |
| 254 | K | A | -2.5306 | |
| 255 | E | A | -2.6386 | |
| 256 | M | A | 0.0000 | |
| 257 | F | A | -0.2492 | |
| 258 | T | A | 0.0000 | |
| 259 | V | A | 0.0000 | |
| 260 | A | A | 0.0000 | |
| 261 | E | A | -0.5259 | |
| 262 | Y | A | 0.2765 | |
| 263 | W | A | 0.6030 | |
| 264 | S | A | 0.4331 | |
| 265 | Y | A | 0.5815 | |
| 266 | D | A | -1.2809 | |
| 267 | L | A | -1.2263 | |
| 268 | G | A | -1.2902 | |
| 269 | A | A | -1.2314 | |
| 270 | L | A | 0.0000 | |
| 271 | E | A | -2.5052 | |
| 272 | N | A | -2.6805 | |
| 273 | Y | A | -1.8135 | |
| 274 | L | A | 0.0000 | |
| 275 | N | A | -3.0805 | |
| 276 | K | A | -2.9071 | |
| 277 | T | A | 0.0000 | |
| 278 | N | A | -2.2094 | |
| 279 | F | A | -0.9391 | |
| 280 | N | A | -1.1124 | |
| 281 | H | A | 0.0000 | |
| 282 | S | A | 0.0724 | |
| 283 | V | A | 0.0000 | |
| 284 | F | A | 0.0000 | |
| 285 | D | A | 0.0000 | |
| 286 | V | A | 0.0000 | |
| 287 | P | A | 0.0000 | |
| 288 | L | A | 0.0000 | |
| 289 | H | A | 0.0000 | |
| 290 | Y | A | 0.2510 | |
| 291 | Q | A | -0.5289 | |
| 292 | F | A | 0.0000 | |
| 293 | H | A | -0.7707 | |
| 294 | A | A | -0.6232 | |
| 295 | A | A | 0.0000 | |
| 296 | S | A | -1.0059 | |
| 297 | T | A | -1.0730 | |
| 298 | Q | A | -1.5091 | |
| 299 | G | A | -1.2641 | |
| 300 | G | A | -1.0135 | |
| 301 | G | A | -1.0796 | |
| 302 | Y | A | -0.8186 | |
| 303 | D | A | -1.2812 | |
| 304 | M | A | 0.0000 | |
| 305 | R | A | -2.2804 | |
| 306 | K | A | -1.9816 | |
| 307 | L | A | 0.0000 | |
| 308 | L | A | -1.2627 | |
| 309 | N | A | -2.1818 | |
| 310 | G | A | -1.7244 | |
| 311 | T | A | 0.0000 | |
| 312 | V | A | 0.0000 | |
| 313 | V | A | -0.5498 | |
| 314 | S | A | -1.1367 | |
| 315 | K | A | -1.9888 | |
| 316 | H | A | -0.7297 | |
| 317 | P | A | -0.2551 | |
| 318 | L | A | 1.0792 | |
| 319 | K | A | 0.0828 | |
| 320 | S | A | 0.0000 | |
| 321 | V | A | 0.0000 | |
| 322 | T | A | 0.0000 | |
| 323 | F | A | 0.0000 | |
| 324 | V | A | 0.0000 | |
| 325 | D | A | 0.0000 | |
| 326 | N | A | -0.3664 | |
| 327 | H | A | 0.0000 | |
| 328 | D | A | -0.6970 | |
| 329 | T | A | 0.0000 | |
| 330 | Q | A | 0.0000 | |
| 331 | P | A | 0.0000 | |
| 332 | G | A | -1.4683 | |
| 333 | Q | A | -0.6638 | |
| 334 | S | A | -0.4243 | |
| 335 | L | A | -0.0545 | |
| 336 | E | A | -0.7204 | |
| 337 | S | A | 0.0000 | |
| 338 | T | A | -0.8517 | |
| 339 | V | A | 0.0000 | |
| 340 | Q | A | -1.4096 | |
| 341 | T | A | -0.4856 | |
| 342 | W | A | -0.1810 | |
| 343 | F | A | 0.0000 | |
| 344 | K | A | 0.0000 | |
| 345 | P | A | -0.5649 | |
| 346 | L | A | 0.0000 | |
| 347 | A | A | 0.0000 | |
| 348 | Y | A | 0.0000 | |
| 349 | A | A | 0.0000 | |
| 350 | F | A | 0.0000 | |
| 351 | I | A | 0.0000 | |
| 352 | L | A | 0.0000 | |
| 353 | T | A | 0.0000 | |
| 354 | R | A | -1.3297 | |
| 355 | E | A | -2.0654 | |
| 356 | S | A | -1.0393 | |
| 357 | G | A | -0.2000 | |
| 358 | Y | A | 0.0316 | |
| 359 | P | A | 0.0000 | |
| 360 | Q | A | 0.0000 | |
| 361 | V | A | 0.0000 | |
| 362 | F | A | 0.0000 | |
| 363 | Y | A | 0.0000 | |
| 364 | G | A | 0.0000 | |
| 365 | D | A | 0.0000 | |
| 366 | M | A | 0.0000 | |
| 367 | Y | A | -0.0986 | |
| 368 | G | A | 0.0000 | |
| 369 | T | A | 0.0000 | |
| 370 | K | A | -1.6122 | |
| 371 | G | A | -1.9807 | |
| 372 | D | A | -2.7195 | |
| 373 | S | A | -2.4165 | |
| 374 | Q | A | -2.5238 | |
| 375 | R | A | -2.7790 | |
| 376 | E | A | -2.2042 | |
| 377 | I | A | 0.0000 | |
| 378 | P | A | -0.5727 | |
| 379 | A | A | -0.4616 | |
| 380 | L | A | 0.0000 | |
| 381 | K | A | -1.7037 | |
| 382 | H | A | -2.2033 | |
| 383 | K | A | -2.5450 | |
| 384 | I | A | 0.0000 | |
| 385 | E | A | -1.4364 | |
| 386 | P | A | -1.0923 | |
| 387 | I | A | 0.0000 | |
| 388 | L | A | 0.0000 | |
| 389 | K | A | -1.0538 | |
| 390 | A | A | 0.0000 | |
| 391 | R | A | 0.0000 | |
| 392 | K | A | -1.1558 | |
| 393 | Q | A | -1.0303 | |
| 394 | Y | A | -0.8957 | |
| 395 | A | A | 0.0000 | |
| 396 | Y | A | 0.0000 | |
| 397 | G | A | -0.9187 | |
| 398 | A | A | -0.7526 | |
| 399 | Q | A | -1.1956 | |
| 400 | H | A | -1.0169 | |
| 401 | D | A | -1.6826 | |
| 402 | Y | A | -1.4059 | |
| 403 | F | A | 0.0000 | |
| 404 | D | A | -2.4663 | |
| 405 | H | A | -1.9398 | |
| 406 | H | A | -1.9362 | |
| 407 | D | A | -1.7911 | |
| 408 | I | A | -1.0764 | |
| 409 | V | A | 0.0000 | |
| 410 | G | A | 0.0000 | |
| 411 | W | A | 0.0000 | |
| 412 | T | A | 0.0000 | |
| 413 | R | A | 0.0000 | |
| 414 | E | A | -1.1315 | |
| 415 | G | A | -1.5027 | |
| 416 | D | A | -1.6743 | |
| 417 | S | A | -1.2112 | |
| 418 | S | A | -0.7199 | |
| 419 | V | A | -0.4528 | |
| 420 | A | A | -0.8292 | |
| 421 | N | A | -1.9133 | |
| 422 | S | A | 0.0000 | |
| 423 | G | A | 0.0000 | |
| 424 | L | A | 0.0000 | |
| 425 | A | A | 0.0000 | |
| 426 | A | A | 0.0000 | |
| 427 | L | A | 0.0000 | |
| 428 | I | A | 0.0000 | |
| 429 | T | A | 0.0000 | |
| 430 | D | A | 0.0000 | |
| 431 | G | A | -1.0055 | |
| 432 | P | A | -1.0075 | |
| 433 | G | A | -1.3101 | |
| 434 | G | A | -0.9545 | |
| 435 | A | A | -1.4390 | |
| 436 | K | A | -1.7692 | |
| 437 | R | A | -2.7426 | |
| 438 | M | A | 0.0000 | |
| 439 | Y | A | -0.8067 | |
| 440 | V | A | 0.0000 | |
| 441 | G | A | 0.0000 | |
| 442 | R | A | -2.5522 | |
| 443 | Q | A | -2.6886 | |
| 444 | N | A | 0.0000 | |
| 445 | A | A | -1.4728 | |
| 446 | G | A | -1.1543 | |
| 447 | E | A | -1.3114 | |
| 448 | T | A | -0.3883 | |
| 449 | W | A | 0.0000 | |
| 450 | H | A | -1.2024 | |
| 451 | D | A | 0.0000 | |
| 452 | I | A | -0.4959 | |
| 453 | T | A | -1.0611 | |
| 454 | G | A | -1.4621 | |
| 455 | N | A | -1.6129 | |
| 456 | R | A | -2.1118 | |
| 457 | S | A | -1.7899 | |
| 458 | E | A | -2.1140 | |
| 459 | P | A | -1.0732 | |
| 460 | V | A | -0.4651 | |
| 461 | V | A | 0.6254 | |
| 462 | I | A | 0.0000 | |
| 463 | N | A | -1.1356 | |
| 464 | S | A | -0.9852 | |
| 465 | A | A | -0.6953 | |
| 466 | G | A | 0.0000 | |
| 467 | W | A | -0.8309 | |
| 468 | G | A | 0.0000 | |
| 469 | E | A | -2.6786 | |
| 470 | F | A | 0.0000 | |
| 471 | H | A | -1.9414 | |
| 472 | V | A | 0.0000 | |
| 473 | N | A | -1.4515 | |
| 474 | G | A | -1.1081 | |
| 475 | G | A | -0.7461 | |
| 476 | S | A | -0.6413 | |
| 477 | V | A | 0.0000 | |
| 478 | S | A | 0.0000 | |
| 479 | I | A | 0.0000 | |
| 480 | Y | A | 0.0000 | |
| 481 | V | A | 0.0000 | |
| 482 | Q | A | -1.3366 | |
| 483 | R | A | -2.0032 |
Calculations for various pH values
This page contains details and comparisons for all models calculated at different pH points.
Please find suggestions on interpreting the results below. More details can be found in the Tutorial.
The input structure is globular. Max score is recommended for pH analysis.
pH |
Average A4D Score |
Max A4D Score |
|||
| 4.0 | -0.5621 | 3.137 | View | CSV | PDB |
| 4.5 | -0.6134 | 2.7787 | View | CSV | PDB |
| 5.0 | -0.6738 | 2.3349 | View | CSV | PDB |
| 5.5 | -0.7319 | 2.0061 | View | CSV | PDB |
| 6.0 | -0.777 | 1.8919 | View | CSV | PDB |
| 6.5 | -0.8032 | 1.7777 | View | CSV | PDB |
| 7.0 | -0.8129 | 1.6642 | View | CSV | PDB |
| 7.5 | -0.8127 | 1.5975 | View | CSV | PDB |
| 8.0 | -0.8066 | 1.7359 | View | CSV | PDB |
| 8.5 | -0.7943 | 1.8756 | View | CSV | PDB |
| 9.0 | -0.7738 | 2.0146 | View | CSV | PDB |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine