| Chain sequence(s) |
A: DQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVANRLQEALKLFDSIWNNKWLRDTSVILFLNIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTNIRRVFNDCRDIIQRMHLRQYELL
B: ELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN G: ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFR N: QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTV P: EEPPISLDLTFHLLREVLEMARAEQLAQQAHSN R: SKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYTTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW input PDB |
| Selected Chain(s) | A,B,G,N,P,R |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| pH calculations | Yes |
| alphaCutter usage | No |
| Dynamic mode | No |
| Automated mutations | No |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:01)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:01)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:01)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:01)
[INFO] PDB-Info: The input structure is globular. Max score is recommended for pH analysis. (00:00:03)
[INFO] FoldX: Starting FoldX energy minimization (00:00:03)
[INFO] Analysis: Starting Aggrescan4D on folded.pdb (00:15:56)
[INFO] agg3D: Running pKa-ANI on
/STORAGE/DATA/lcbio/aggreskan/9560dca4e9f632a/tmp/folded.pdb (00:15:56)
[INFO] Main: Simulation completed successfully. (00:21:17)
|
The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan4D score | mutation |
|---|---|---|---|---|
| 11 | D | A | -4.0451 | |
| 12 | Q | A | -4.3210 | |
| 13 | R | A | -4.9225 | |
| 14 | N | A | -5.0976 | |
| 15 | E | A | -5.3375 | |
| 16 | E | A | -5.0828 | |
| 17 | K | A | -5.0080 | |
| 18 | A | A | -3.6184 | |
| 19 | Q | A | -3.6169 | |
| 20 | R | A | -4.6978 | |
| 21 | E | A | -4.4151 | |
| 22 | A | A | -2.9645 | |
| 23 | N | A | -3.3478 | |
| 24 | K | A | -4.3989 | |
| 25 | K | A | -4.0978 | |
| 26 | I | A | -2.8654 | |
| 27 | E | A | -3.3839 | |
| 28 | K | A | -4.2971 | |
| 29 | Q | A | -3.7267 | |
| 30 | L | A | 0.0000 | |
| 31 | Q | A | -3.1631 | |
| 32 | K | A | -3.2206 | |
| 33 | D | A | -2.2149 | |
| 34 | K | A | -2.3542 | |
| 35 | Q | A | -2.0342 | |
| 36 | V | A | 0.0221 | |
| 37 | Y | A | -0.7264 | |
| 38 | R | A | -1.7265 | |
| 39 | A | A | -0.8944 | |
| 40 | T | A | 0.0000 | |
| 41 | H | A | 0.0000 | |
| 42 | R | A | -1.0214 | |
| 43 | L | A | 0.0000 | |
| 44 | L | A | 0.0000 | |
| 45 | L | A | -0.0344 | |
| 46 | L | A | 0.0000 | |
| 47 | G | A | -0.3321 | |
| 205 | S | A | -0.1708 | |
| 206 | G | A | 0.0000 | |
| 207 | I | A | 0.0000 | |
| 208 | F | A | 0.2712 | |
| 209 | E | A | -1.2479 | |
| 210 | T | A | -1.3439 | |
| 211 | K | A | -2.1619 | |
| 212 | F | A | -1.3142 | |
| 213 | Q | A | -2.2336 | |
| 214 | V | A | 0.0000 | |
| 215 | D | A | -2.9780 | |
| 216 | K | A | -2.8467 | |
| 217 | V | A | -1.6793 | |
| 218 | N | A | -1.5937 | |
| 219 | F | A | 0.0000 | |
| 220 | H | A | -1.3788 | |
| 221 | M | A | -0.6199 | |
| 222 | F | A | 0.0000 | |
| 223 | D | A | -0.5401 | |
| 224 | V | A | 0.0000 | |
| 225 | G | A | -0.5203 | |
| 226 | G | A | -0.6682 | |
| 227 | Q | A | -0.8943 | |
| 228 | R | A | -0.9977 | |
| 229 | D | A | -1.0087 | |
| 230 | E | A | 0.0000 | |
| 231 | R | A | -0.7055 | |
| 232 | R | A | -0.4422 | |
| 233 | K | A | 0.0000 | |
| 234 | W | A | 0.0000 | |
| 235 | I | A | 0.0000 | |
| 236 | Q | A | -0.6186 | |
| 237 | C | A | 0.0000 | |
| 238 | F | A | 0.0000 | |
| 239 | N | A | -1.6620 | |
| 240 | D | A | -2.1706 | |
| 241 | V | A | 0.0000 | |
| 242 | T | A | -0.7625 | |
| 243 | A | A | 0.0000 | |
| 244 | I | A | 0.0000 | |
| 245 | I | A | 0.0000 | |
| 246 | F | A | 0.0000 | |
| 247 | V | A | 0.0028 | |
| 248 | V | A | 0.0000 | |
| 249 | A | A | -0.7319 | |
| 264 | N | A | -2.1138 | |
| 265 | R | A | -2.7988 | |
| 266 | L | A | 0.0000 | |
| 267 | Q | A | -1.7218 | |
| 268 | E | A | -2.6901 | |
| 269 | A | A | -1.5193 | |
| 270 | L | A | 0.0000 | |
| 271 | K | A | -0.7522 | |
| 272 | L | A | -0.5159 | |
| 273 | F | A | 0.0000 | |
| 274 | D | A | -0.8694 | |
| 275 | S | A | 0.0000 | |
| 276 | I | A | 0.0000 | |
| 277 | W | A | 0.0000 | |
| 278 | N | A | -1.4374 | |
| 279 | N | A | -1.5886 | |
| 280 | K | A | -1.7831 | |
| 281 | W | A | -1.3809 | |
| 282 | L | A | 0.0000 | |
| 283 | R | A | -2.7820 | |
| 284 | D | A | -3.0565 | |
| 285 | T | A | 0.0000 | |
| 286 | S | A | 0.0000 | |
| 287 | V | A | 0.0000 | |
| 288 | I | A | 0.0000 | |
| 289 | L | A | 0.0000 | |
| 290 | F | A | 0.0000 | |
| 291 | L | A | 0.0000 | |
| 292 | N | A | -1.1810 | |
| 308 | I | A | -0.4579 | |
| 309 | E | A | -2.2885 | |
| 310 | D | A | -2.1884 | |
| 311 | Y | A | -0.8352 | |
| 312 | F | A | 0.0000 | |
| 313 | P | A | -2.0232 | |
| 314 | E | A | -2.5585 | |
| 315 | F | A | 0.0000 | |
| 316 | A | A | -1.9007 | |
| 317 | R | A | -2.1950 | |
| 318 | Y | A | -1.1562 | |
| 319 | T | A | -0.7713 | |
| 320 | T | A | -1.1482 | |
| 321 | P | A | -1.6394 | |
| 322 | E | A | -2.7566 | |
| 323 | D | A | -2.7355 | |
| 324 | A | A | -1.8086 | |
| 325 | T | A | -1.3042 | |
| 326 | P | A | -1.6254 | |
| 327 | E | A | -2.2611 | |
| 328 | P | A | -1.6852 | |
| 329 | G | A | -1.5743 | |
| 330 | E | A | -1.9676 | |
| 331 | D | A | -1.8948 | |
| 332 | P | A | -1.7528 | |
| 333 | R | A | -2.2491 | |
| 334 | V | A | -1.0233 | |
| 335 | T | A | 0.0000 | |
| 336 | R | A | -1.1105 | |
| 337 | A | A | -0.6964 | |
| 338 | K | A | -0.6533 | |
| 339 | Y | A | -0.2016 | |
| 340 | F | A | 0.0000 | |
| 341 | I | A | 0.0112 | |
| 342 | R | A | -0.6023 | |
| 343 | D | A | -0.8283 | |
| 344 | E | A | -0.7608 | |
| 345 | F | A | 0.0000 | |
| 346 | L | A | -0.5311 | |
| 347 | R | A | -1.6942 | |
| 348 | I | A | -0.5710 | |
| 349 | S | A | 0.0000 | |
| 350 | T | A | -0.6675 | |
| 351 | A | A | -0.5904 | |
| 352 | S | A | -1.0867 | |
| 353 | G | A | -1.4375 | |
| 354 | D | A | -2.4629 | |
| 355 | G | A | -1.7963 | |
| 356 | R | A | -2.3147 | |
| 357 | H | A | 0.0000 | |
| 358 | Y | A | -0.3302 | |
| 359 | C | A | 0.4539 | |
| 360 | Y | A | 0.1754 | |
| 361 | P | A | 0.1139 | |
| 362 | H | A | -0.4695 | |
| 363 | F | A | -0.3712 | |
| 364 | T | A | -0.6104 | |
| 371 | N | A | -0.9696 | |
| 372 | I | A | 0.0872 | |
| 373 | R | A | -1.4317 | |
| 374 | R | A | -1.5658 | |
| 375 | V | A | 0.0000 | |
| 376 | F | A | 0.0000 | |
| 377 | N | A | -1.7866 | |
| 378 | D | A | 0.0000 | |
| 379 | C | A | 0.0000 | |
| 380 | R | A | -0.9599 | |
| 381 | D | A | -0.7436 | |
| 382 | I | A | -0.2460 | |
| 383 | I | A | 0.0000 | |
| 384 | Q | A | -0.0995 | |
| 385 | R | A | 0.0000 | |
| 386 | M | A | -0.4543 | |
| 387 | H | A | -0.3759 | |
| 388 | L | A | 0.0000 | |
| 389 | R | A | -0.9922 | |
| 390 | Q | A | -1.2372 | |
| 391 | Y | A | 0.0000 | |
| 392 | E | A | -0.7996 | |
| 393 | L | A | 0.0000 | |
| 394 | L | A | -0.0284 | |
| 3 | E | B | -2.6510 | |
| 4 | L | B | -0.9750 | |
| 5 | D | B | -3.2320 | |
| 6 | Q | B | -3.6573 | |
| 7 | L | B | 0.0000 | |
| 8 | R | B | -3.8687 | |
| 9 | Q | B | -4.0561 | |
| 10 | E | B | -4.3382 | |
| 11 | A | B | 0.0000 | |
| 12 | E | B | -3.3479 | |
| 13 | Q | B | -3.5511 | |
| 14 | L | B | -2.9507 | |
| 15 | K | B | -3.2296 | |
| 16 | N | B | -3.4787 | |
| 17 | Q | B | -3.4783 | |
| 18 | I | B | 0.0000 | |
| 19 | R | B | -4.1866 | |
| 20 | D | B | -4.0098 | |
| 21 | A | B | -2.7598 | |
| 22 | R | B | -2.8127 | |
| 23 | K | B | -3.4196 | |
| 24 | A | B | -2.0608 | |
| 25 | C | B | 0.0000 | |
| 26 | A | B | -2.1282 | |
| 27 | D | B | -2.4456 | |
| 28 | A | B | -1.4139 | |
| 29 | T | B | -0.8490 | |
| 30 | L | B | 0.0000 | |
| 31 | S | B | -1.1201 | |
| 32 | Q | B | -1.6236 | |
| 33 | I | B | -0.6950 | |
| 34 | T | B | 0.0000 | |
| 35 | N | B | -2.4274 | |
| 36 | N | B | -2.3465 | |
| 37 | I | B | -1.7773 | |
| 38 | D | B | -2.3077 | |
| 39 | P | B | -1.8762 | |
| 40 | V | B | -1.1700 | |
| 41 | G | B | -1.6262 | |
| 42 | R | B | -2.3338 | |
| 43 | I | B | 0.0000 | |
| 44 | Q | B | -2.0837 | |
| 45 | M | B | 0.0000 | |
| 46 | R | B | -2.2579 | |
| 47 | T | B | -1.2587 | |
| 48 | R | B | -1.4000 | |
| 49 | R | B | -1.1146 | |
| 50 | T | B | -0.6761 | |
| 51 | L | B | 0.0000 | |
| 52 | R | B | -1.8546 | |
| 53 | G | B | -1.2756 | |
| 54 | H | B | 0.0000 | |
| 55 | L | B | 0.0000 | |
| 56 | A | B | -0.4005 | |
| 57 | K | B | 0.0000 | |
| 58 | I | B | 0.0000 | |
| 59 | Y | B | 0.1684 | |
| 60 | A | B | 0.0517 | |
| 61 | M | B | 0.0000 | |
| 62 | H | B | -0.2389 | |
| 63 | W | B | 0.0000 | |
| 64 | G | B | 0.0000 | |
| 65 | T | B | -1.9112 | |
| 66 | D | B | -2.7351 | |
| 67 | S | B | 0.0000 | |
| 68 | R | B | -1.5267 | |
| 69 | L | B | -0.5264 | |
| 70 | L | B | 0.0000 | |
| 71 | V | B | 0.0000 | |
| 72 | S | B | 0.0000 | |
| 73 | A | B | 0.0000 | |
| 74 | S | B | 0.0000 | |
| 75 | Q | B | 0.0000 | |
| 76 | D | B | -0.3148 | |
| 77 | G | B | 0.0000 | |
| 78 | K | B | 0.0000 | |
| 79 | L | B | 0.0000 | |
| 80 | I | B | 0.0000 | |
| 81 | I | B | 0.0000 | |
| 82 | W | B | 0.0000 | |
| 83 | D | B | 0.0000 | |
| 84 | S | B | 0.0000 | |
| 85 | Y | B | -0.0700 | |
| 86 | T | B | -0.3303 | |
| 87 | T | B | -0.4490 | |
| 88 | N | B | 0.0000 | |
| 89 | K | B | 0.0000 | |
| 90 | V | B | -0.0565 | |
| 91 | H | B | -0.1768 | |
| 92 | A | B | -0.1963 | |
| 93 | I | B | 0.0000 | |
| 94 | P | B | -0.6559 | |
| 95 | L | B | -0.7882 | |
| 96 | R | B | -1.8710 | |
| 97 | S | B | 0.0000 | |
| 98 | S | B | -0.7117 | |
| 99 | W | B | 0.0000 | |
| 100 | V | B | 0.0000 | |
| 101 | M | B | 0.1669 | |
| 102 | T | B | 0.0000 | |
| 103 | C | B | 0.0000 | |
| 104 | A | B | 0.0000 | |
| 105 | Y | B | 0.0000 | |
| 106 | A | B | 0.0000 | |
| 107 | P | B | -1.0364 | |
| 108 | S | B | -1.0103 | |
| 109 | G | B | -0.8916 | |
| 110 | N | B | -1.0391 | |
| 111 | Y | B | -0.8209 | |
| 112 | V | B | 0.0000 | |
| 113 | A | B | 0.0000 | |
| 114 | C | B | 0.0000 | |
| 115 | G | B | 0.0000 | |
| 116 | G | B | 0.0000 | |
| 117 | L | B | 0.0000 | |
| 118 | D | B | -0.4193 | |
| 119 | N | B | -0.4422 | |
| 120 | I | B | -0.2241 | |
| 121 | C | B | 0.0000 | |
| 122 | S | B | -0.4345 | |
| 123 | I | B | 0.0000 | |
| 124 | Y | B | 0.0000 | |
| 125 | N | B | -1.1619 | |
| 126 | L | B | 0.0000 | |
| 127 | K | B | -2.8822 | |
| 128 | T | B | -2.9505 | |
| 129 | R | B | -3.3331 | |
| 130 | E | B | -3.4504 | |
| 131 | G | B | -2.6757 | |
| 132 | N | B | -2.1038 | |
| 133 | V | B | -1.6359 | |
| 134 | R | B | -1.9976 | |
| 135 | V | B | -0.3682 | |
| 136 | S | B | -0.8673 | |
| 137 | R | B | -1.4137 | |
| 138 | E | B | -0.9434 | |
| 139 | L | B | 0.0000 | |
| 140 | A | B | -0.7162 | |
| 141 | G | B | -0.7757 | |
| 142 | H | B | 0.0000 | |
| 143 | T | B | -0.4877 | |
| 144 | G | B | 0.0000 | |
| 145 | Y | B | 0.0000 | |
| 146 | L | B | 0.0000 | |
| 147 | S | B | 0.0000 | |
| 148 | C | B | 0.0611 | |
| 149 | C | B | 0.0000 | |
| 150 | R | B | -0.6177 | |
| 151 | F | B | 0.0000 | |
| 152 | L | B | -1.4201 | |
| 153 | D | B | -2.3607 | |
| 154 | D | B | -2.0429 | |
| 155 | N | B | -2.1295 | |
| 156 | Q | B | -1.7767 | |
| 157 | I | B | 0.0000 | |
| 158 | V | B | 0.0000 | |
| 159 | T | B | 0.0000 | |
| 160 | S | B | 0.0000 | |
| 161 | S | B | 0.0000 | |
| 162 | G | B | 0.0000 | |
| 163 | D | B | -0.5162 | |
| 164 | T | B | -0.3596 | |
| 165 | T | B | -0.2752 | |
| 166 | C | B | 0.0000 | |
| 167 | A | B | 0.0000 | |
| 168 | L | B | 0.0000 | |
| 169 | W | B | 0.0000 | |
| 170 | D | B | -1.9135 | |
| 171 | I | B | 0.0000 | |
| 172 | E | B | -2.5460 | |
| 173 | T | B | -1.6685 | |
| 174 | G | B | -1.8974 | |
| 175 | Q | B | -1.9143 | |
| 176 | Q | B | -1.2874 | |
| 177 | T | B | -0.9647 | |
| 178 | T | B | -0.9417 | |
| 179 | T | B | -0.2085 | |
| 180 | F | B | 0.0000 | |
| 181 | T | B | -0.3149 | |
| 182 | G | B | -0.7069 | |
| 183 | H | B | 0.0000 | |
| 184 | T | B | -0.2784 | |
| 185 | G | B | 0.0000 | |
| 186 | D | B | 0.0000 | |
| 187 | V | B | 0.0000 | |
| 188 | M | B | 0.0850 | |
| 189 | S | B | 0.0000 | |
| 190 | L | B | 0.0000 | |
| 191 | S | B | 0.0000 | |
| 192 | L | B | -0.3658 | |
| 193 | A | B | 0.0000 | |
| 194 | P | B | -1.4037 | |
| 195 | D | B | -2.2912 | |
| 196 | T | B | -1.8399 | |
| 197 | R | B | -2.3378 | |
| 198 | L | B | -1.3166 | |
| 199 | F | B | 0.0000 | |
| 200 | V | B | 0.0000 | |
| 201 | S | B | 0.0000 | |
| 202 | G | B | 0.0000 | |
| 203 | A | B | 0.0000 | |
| 204 | C | B | 0.0000 | |
| 205 | D | B | -0.3565 | |
| 206 | A | B | 0.0000 | |
| 207 | S | B | 0.0000 | |
| 208 | A | B | 0.0000 | |
| 209 | K | B | 0.0000 | |
| 210 | L | B | 0.0000 | |
| 211 | W | B | 0.0000 | |
| 212 | D | B | 0.0000 | |
| 213 | V | B | 0.0000 | |
| 214 | R | B | -2.9480 | |
| 215 | E | B | -2.7516 | |
| 216 | G | B | -1.4057 | |
| 217 | M | B | -0.6690 | |
| 218 | C | B | 0.0000 | |
| 219 | R | B | -0.4764 | |
| 220 | Q | B | -0.3333 | |
| 221 | T | B | -0.2834 | |
| 222 | F | B | 0.0000 | |
| 223 | T | B | -0.5988 | |
| 224 | G | B | -0.7196 | |
| 225 | H | B | 0.0000 | |
| 226 | E | B | -0.7766 | |
| 227 | S | B | 0.0000 | |
| 228 | D | B | 0.0000 | |
| 229 | I | B | 0.0000 | |
| 230 | N | B | -0.2066 | |
| 231 | A | B | 0.0000 | |
| 232 | I | B | 0.0000 | |
| 233 | C | B | 0.1229 | |
| 234 | F | B | 0.0000 | |
| 235 | F | B | 0.0000 | |
| 236 | P | B | -0.4452 | |
| 237 | N | B | -0.9087 | |
| 238 | G | B | -0.7584 | |
| 239 | N | B | -0.8255 | |
| 240 | A | B | 0.0000 | |
| 241 | F | B | 0.0000 | |
| 242 | A | B | 0.0000 | |
| 243 | T | B | 0.0000 | |
| 244 | G | B | 0.0000 | |
| 245 | S | B | 0.0000 | |
| 246 | D | B | -0.1384 | |
| 247 | D | B | 0.1120 | |
| 248 | A | B | 0.0000 | |
| 249 | T | B | -0.0468 | |
| 250 | C | B | 0.0000 | |
| 251 | R | B | -0.3586 | |
| 252 | L | B | 0.0000 | |
| 253 | F | B | 0.0000 | |
| 254 | D | B | 0.0000 | |
| 255 | L | B | 0.0000 | |
| 256 | R | B | -0.9035 | |
| 257 | A | B | 0.0000 | |
| 258 | D | B | 0.0000 | |
| 259 | Q | B | -0.9615 | |
| 260 | E | B | -0.5950 | |
| 261 | L | B | 0.0000 | |
| 262 | M | B | 0.0000 | |
| 263 | T | B | -0.3452 | |
| 264 | Y | B | 0.0000 | |
| 265 | S | B | -1.0658 | |
| 266 | H | B | -1.8380 | |
| 267 | D | B | -2.2909 | |
| 268 | N | B | -1.8060 | |
| 269 | I | B | 0.0000 | |
| 270 | I | B | 1.2630 | |
| 271 | C | B | 0.7302 | |
| 272 | G | B | 0.0000 | |
| 273 | I | B | 0.0000 | |
| 274 | T | B | -0.1070 | |
| 275 | S | B | 0.0000 | |
| 276 | V | B | 0.0000 | |
| 277 | S | B | -0.0124 | |
| 278 | F | B | 0.0000 | |
| 279 | S | B | 0.0000 | |
| 280 | K | B | -1.7244 | |
| 281 | S | B | 0.0000 | |
| 282 | G | B | 0.0000 | |
| 283 | R | B | 0.0000 | |
| 284 | L | B | 0.0000 | |
| 285 | L | B | 0.0000 | |
| 286 | L | B | 0.0000 | |
| 287 | A | B | 0.0000 | |
| 288 | G | B | 0.0000 | |
| 289 | Y | B | 0.0000 | |
| 290 | D | B | 0.0000 | |
| 291 | D | B | -0.9267 | |
| 292 | F | B | -0.6874 | |
| 293 | N | B | -0.4013 | |
| 294 | C | B | 0.0000 | |
| 295 | N | B | 0.0000 | |
| 296 | V | B | 0.0000 | |
| 297 | W | B | 0.0000 | |
| 298 | D | B | 0.0000 | |
| 299 | A | B | 0.0000 | |
| 300 | L | B | 0.0000 | |
| 301 | K | B | -1.7263 | |
| 302 | A | B | -1.3534 | |
| 303 | D | B | -2.3323 | |
| 304 | R | B | -1.8643 | |
| 305 | A | B | -1.5873 | |
| 306 | G | B | 0.0000 | |
| 307 | V | B | -0.2338 | |
| 308 | L | B | 0.0000 | |
| 309 | A | B | -0.9368 | |
| 310 | G | B | -1.0413 | |
| 311 | H | B | 0.0000 | |
| 312 | D | B | -1.6330 | |
| 313 | N | B | -1.1526 | |
| 314 | R | B | 0.0000 | |
| 315 | V | B | 0.0000 | |
| 316 | S | B | 0.0085 | |
| 317 | C | B | 0.0000 | |
| 318 | L | B | 0.0000 | |
| 319 | G | B | -0.2100 | |
| 320 | V | B | -0.6137 | |
| 321 | T | B | 0.0000 | |
| 322 | D | B | -3.1737 | |
| 323 | D | B | -3.2477 | |
| 324 | G | B | 0.0000 | |
| 325 | M | B | -0.9857 | |
| 326 | A | B | 0.0000 | |
| 327 | V | B | 0.0000 | |
| 328 | A | B | 0.0000 | |
| 329 | T | B | 0.0000 | |
| 330 | G | B | 0.0000 | |
| 331 | S | B | 0.0000 | |
| 332 | W | B | 0.0000 | |
| 333 | D | B | -0.6235 | |
| 334 | S | B | -0.5814 | |
| 335 | F | B | -0.5967 | |
| 336 | L | B | 0.0000 | |
| 337 | K | B | 0.0000 | |
| 338 | I | B | 0.0000 | |
| 339 | W | B | 0.0000 | |
| 340 | N | B | 0.0000 | |
| 7 | A | G | 0.1745 | |
| 8 | S | G | -0.2328 | |
| 9 | I | G | -0.9830 | |
| 10 | A | G | -1.2349 | |
| 11 | Q | G | -1.9251 | |
| 12 | A | G | -2.0312 | |
| 13 | R | G | -3.1258 | |
| 14 | K | G | -2.8516 | |
| 15 | L | G | -1.4483 | |
| 16 | V | G | 0.0000 | |
| 17 | E | G | -2.2476 | |
| 18 | Q | G | -1.4972 | |
| 19 | L | G | -1.6844 | |
| 20 | K | G | -1.7874 | |
| 21 | M | G | -0.9833 | |
| 22 | E | G | 0.0000 | |
| 23 | A | G | -1.5021 | |
| 24 | N | G | -1.5975 | |
| 25 | I | G | -1.1695 | |
| 26 | D | G | -1.8424 | |
| 27 | R | G | -1.1247 | |
| 28 | I | G | -0.8731 | |
| 29 | K | G | -1.8468 | |
| 30 | V | G | 0.0000 | |
| 31 | S | G | -1.6528 | |
| 32 | K | G | -2.3338 | |
| 33 | A | G | 0.0000 | |
| 34 | A | G | 0.0000 | |
| 35 | A | G | -0.8924 | |
| 36 | D | G | -1.6950 | |
| 37 | L | G | 0.0000 | |
| 38 | M | G | -0.5528 | |
| 39 | A | G | -0.8055 | |
| 40 | Y | G | -0.6470 | |
| 41 | C | G | 0.0000 | |
| 42 | E | G | -2.0783 | |
| 43 | A | G | -1.3877 | |
| 44 | H | G | -1.8658 | |
| 45 | A | G | -2.0751 | |
| 46 | K | G | -2.8439 | |
| 47 | E | G | -2.9299 | |
| 48 | D | G | 0.0000 | |
| 49 | P | G | -1.0788 | |
| 50 | L | G | 0.0000 | |
| 51 | L | G | -0.6872 | |
| 52 | T | G | -0.7360 | |
| 53 | P | G | -0.4240 | |
| 54 | V | G | -0.6503 | |
| 55 | P | G | -0.9581 | |
| 56 | A | G | -1.2038 | |
| 57 | S | G | -1.4033 | |
| 58 | E | G | -2.1751 | |
| 59 | N | G | 0.0000 | |
| 60 | P | G | -1.1277 | |
| 61 | F | G | 0.0000 | |
| 62 | R | G | -2.2271 | |
| 1 | Q | N | -1.5795 | |
| 2 | V | N | -1.0885 | |
| 3 | Q | N | -1.7567 | |
| 4 | L | N | 0.0000 | |
| 5 | Q | N | -1.7841 | |
| 6 | E | N | 0.0000 | |
| 7 | S | N | -1.0659 | |
| 8 | G | N | -1.2029 | |
| 9 | G | N | 0.0000 | |
| 10 | G | N | -0.0831 | |
| 11 | L | N | 1.0658 | |
| 12 | V | N | 0.0126 | |
| 13 | Q | N | -1.2583 | |
| 14 | P | N | -1.6285 | |
| 15 | G | N | -1.5164 | |
| 16 | G | N | -0.9558 | |
| 17 | S | N | -1.2209 | |
| 18 | L | N | -0.8124 | |
| 19 | R | N | -1.7595 | |
| 20 | L | N | 0.0000 | |
| 21 | S | N | -0.7371 | |
| 22 | C | N | 0.0000 | |
| 23 | A | N | -0.9535 | |
| 24 | A | N | 0.0000 | |
| 25 | S | N | -1.0860 | |
| 26 | G | N | -1.0520 | |
| 27 | F | N | 0.0000 | |
| 28 | T | N | -0.4400 | |
| 29 | F | N | 0.0000 | |
| 30 | S | N | -0.7901 | |
| 31 | N | N | -0.2391 | |
| 32 | Y | N | 0.0000 | |
| 33 | K | N | -0.5208 | |
| 34 | M | N | 0.0000 | |
| 35 | N | N | 0.0000 | |
| 36 | W | N | 0.0000 | |
| 37 | V | N | 0.0000 | |
| 38 | R | N | 0.0000 | |
| 39 | Q | N | -1.2091 | |
| 40 | A | N | -1.5174 | |
| 41 | P | N | -1.1085 | |
| 42 | G | N | -1.5649 | |
| 43 | K | N | -2.4517 | |
| 44 | G | N | -1.6984 | |
| 45 | L | N | -1.0691 | |
| 46 | E | N | -1.6005 | |
| 47 | W | N | 0.0000 | |
| 48 | V | N | 0.0000 | |
| 49 | S | N | 0.0000 | |
| 50 | D | N | 0.0000 | |
| 51 | I | N | 0.0000 | |
| 52 | S | N | -0.4639 | |
| 53 | Q | N | -0.7510 | |
| 54 | S | N | -0.6283 | |
| 55 | G | N | -0.3880 | |
| 56 | A | N | -0.0044 | |
| 57 | S | N | 0.0944 | |
| 58 | I | N | 0.7148 | |
| 59 | S | N | 0.1710 | |
| 60 | Y | N | -0.2355 | |
| 61 | T | N | 0.0000 | |
| 62 | G | N | -1.0803 | |
| 63 | S | N | -1.1704 | |
| 64 | V | N | 0.0000 | |
| 65 | K | N | -2.1923 | |
| 66 | G | N | -1.5484 | |
| 67 | R | N | -1.3880 | |
| 68 | F | N | 0.0000 | |
| 69 | T | N | -0.6609 | |
| 70 | I | N | 0.0000 | |
| 71 | S | N | -0.2088 | |
| 72 | R | N | -0.9311 | |
| 73 | D | N | -1.3716 | |
| 74 | N | N | -1.5808 | |
| 75 | A | N | -1.3067 | |
| 76 | K | N | -2.2463 | |
| 77 | N | N | -1.7699 | |
| 78 | T | N | -1.1550 | |
| 79 | L | N | 0.0000 | |
| 80 | Y | N | -0.3520 | |
| 81 | L | N | 0.0000 | |
| 82 | Q | N | -1.1101 | |
| 83 | M | N | 0.0000 | |
| 84 | N | N | -1.4643 | |
| 85 | S | N | -1.4029 | |
| 86 | L | N | 0.0000 | |
| 87 | K | N | -2.6716 | |
| 88 | P | N | -2.0068 | |
| 89 | E | N | -2.3796 | |
| 90 | D | N | 0.0000 | |
| 91 | T | N | -0.8723 | |
| 92 | A | N | 0.0000 | |
| 93 | V | N | -0.5185 | |
| 94 | Y | N | 0.0000 | |
| 95 | Y | N | -0.4991 | |
| 96 | C | N | 0.0000 | |
| 97 | A | N | 0.0000 | |
| 98 | R | N | 0.0000 | |
| 99 | C | N | 0.0000 | |
| 100 | P | N | 0.0000 | |
| 101 | A | N | -0.1470 | |
| 102 | P | N | 0.0000 | |
| 103 | F | N | 0.9854 | |
| 104 | T | N | -0.6045 | |
| 105 | R | N | -1.8654 | |
| 106 | D | N | 0.0000 | |
| 107 | C | N | -0.3326 | |
| 108 | F | N | 0.1013 | |
| 109 | D | N | 0.0000 | |
| 110 | V | N | -0.1184 | |
| 111 | T | N | 0.0000 | |
| 112 | S | N | -0.4930 | |
| 113 | T | N | -0.3594 | |
| 114 | T | N | -0.2484 | |
| 115 | Y | N | 0.0000 | |
| 116 | A | N | -0.2215 | |
| 117 | Y | N | 0.0000 | |
| 118 | R | N | -0.7456 | |
| 119 | G | N | -1.2587 | |
| 120 | Q | N | -1.8545 | |
| 121 | G | N | -1.1400 | |
| 122 | T | N | -1.1434 | |
| 123 | Q | N | -1.2014 | |
| 124 | V | N | 0.0000 | |
| 125 | T | N | -0.2094 | |
| 126 | V | N | -0.6005 | |
| 112 | S | R | -0.6247 | |
| 113 | K | R | -1.0262 | |
| 114 | V | R | 0.7069 | |
| 115 | H | R | 0.3808 | |
| 116 | Y | R | 0.0000 | |
| 117 | H | R | 0.2535 | |
| 118 | V | R | 1.3474 | |
| 119 | A | R | 0.0000 | |
| 120 | V | R | 1.6874 | |
| 121 | I | R | 2.8650 | |
| 122 | I | R | 2.4426 | |
| 123 | N | R | 0.0000 | |
| 124 | Y | R | 2.2339 | |
| 125 | L | R | 2.4946 | |
| 126 | G | R | 0.0000 | |
| 127 | H | R | 0.0000 | |
| 128 | C | R | 1.8902 | |
| 129 | I | R | 1.9539 | |
| 130 | S | R | 0.0000 | |
| 131 | L | R | 2.0891 | |
| 132 | V | R | 2.9096 | |
| 133 | A | R | 0.0000 | |
| 134 | L | R | 0.0000 | |
| 135 | L | R | 2.2833 | |
| 136 | V | R | 2.2827 | |
| 137 | A | R | 0.0000 | |
| 138 | F | R | 1.5731 | |
| 139 | V | R | 1.0454 | |
| 140 | L | R | 0.4250 | |
| 141 | F | R | 0.0000 | |
| 142 | L | R | -0.1187 | |
| 143 | R | R | -1.5354 | |
| 144 | L | R | 0.0000 | |
| 145 | R | R | -1.8715 | |
| 146 | S | R | -1.3402 | |
| 147 | I | R | 0.0000 | |
| 148 | R | R | -0.9885 | |
| 149 | C | R | -0.1903 | |
| 150 | L | R | -0.0922 | |
| 151 | R | R | 0.0000 | |
| 152 | N | R | 0.0000 | |
| 153 | I | R | 0.0000 | |
| 154 | I | R | 0.0000 | |
| 155 | H | R | 0.0000 | |
| 156 | W | R | 0.4006 | |
| 157 | N | R | 0.1444 | |
| 158 | L | R | 0.0000 | |
| 159 | I | R | 0.0000 | |
| 160 | S | R | 0.4547 | |
| 161 | A | R | 0.0000 | |
| 162 | F | R | 0.0000 | |
| 163 | I | R | 1.0746 | |
| 164 | L | R | 0.8959 | |
| 165 | R | R | 0.0000 | |
| 166 | N | R | 0.0000 | |
| 167 | A | R | 0.8390 | |
| 168 | T | R | 0.7968 | |
| 169 | W | R | 0.0000 | |
| 170 | F | R | 1.4270 | |
| 171 | V | R | 1.7285 | |
| 172 | V | R | 0.0000 | |
| 173 | Q | R | 1.0756 | |
| 174 | L | R | 1.8586 | |
| 175 | T | R | 1.1356 | |
| 176 | M | R | 0.0000 | |
| 177 | S | R | -0.6768 | |
| 178 | P | R | -1.7585 | |
| 179 | E | R | -2.2909 | |
| 180 | V | R | 0.0000 | |
| 181 | H | R | 0.0000 | |
| 182 | Q | R | -2.2553 | |
| 183 | S | R | -1.5771 | |
| 184 | N | R | -1.2967 | |
| 185 | V | R | 0.0084 | |
| 186 | G | R | 0.5266 | |
| 187 | W | R | 1.4867 | |
| 188 | C | R | 0.0000 | |
| 189 | R | R | 0.5359 | |
| 190 | L | R | 1.7476 | |
| 191 | V | R | 0.0000 | |
| 192 | T | R | 0.0000 | |
| 193 | A | R | 0.8594 | |
| 194 | A | R | 0.5644 | |
| 195 | Y | R | 0.0000 | |
| 196 | N | R | 0.0000 | |
| 197 | Y | R | 0.0000 | |
| 198 | F | R | 0.7684 | |
| 199 | H | R | 0.0000 | |
| 200 | V | R | 0.0000 | |
| 201 | T | R | 0.0000 | |
| 202 | N | R | 0.0000 | |
| 203 | F | R | 0.0000 | |
| 204 | F | R | 0.6804 | |
| 205 | W | R | 0.0000 | |
| 206 | M | R | 0.0000 | |
| 207 | F | R | 0.8201 | |
| 208 | G | R | 0.0000 | |
| 209 | E | R | 0.0000 | |
| 210 | G | R | 0.0000 | |
| 211 | C | R | 0.4374 | |
| 212 | Y | R | 0.4235 | |
| 213 | L | R | 0.0000 | |
| 214 | H | R | 0.7262 | |
| 215 | T | R | 0.2164 | |
| 216 | A | R | 0.0000 | |
| 217 | I | R | 0.0000 | |
| 218 | V | R | 0.7703 | |
| 219 | L | R | 0.8101 | |
| 220 | T | R | 0.0000 | |
| 221 | Y | R | -0.5577 | |
| 222 | T | R | -0.5301 | |
| 223 | T | R | -0.9060 | |
| 224 | D | R | -1.9358 | |
| 225 | R | R | -2.6466 | |
| 226 | L | R | -1.2491 | |
| 227 | R | R | -1.2439 | |
| 228 | K | R | -0.9199 | |
| 229 | W | R | 0.8513 | |
| 230 | M | R | 0.6503 | |
| 231 | F | R | 0.0000 | |
| 232 | I | R | 1.2092 | |
| 233 | C | R | 1.3191 | |
| 234 | I | R | 1.5573 | |
| 235 | G | R | 0.0000 | |
| 236 | W | R | 1.1556 | |
| 237 | G | R | 1.2539 | |
| 238 | V | R | 1.6094 | |
| 239 | P | R | 0.0000 | |
| 240 | F | R | 2.5646 | |
| 241 | P | R | 1.5252 | |
| 242 | I | R | 1.7498 | |
| 243 | I | R | 0.0000 | |
| 244 | V | R | 2.7721 | |
| 245 | A | R | 2.1329 | |
| 246 | W | R | 0.0000 | |
| 247 | A | R | 2.4651 | |
| 248 | I | R | 3.4137 | |
| 249 | G | R | 2.3841 | |
| 250 | K | R | 0.0000 | |
| 251 | L | R | 2.7706 | |
| 252 | Y | R | 3.0096 | |
| 253 | Y | R | 2.3491 | |
| 254 | D | R | 0.2625 | |
| 255 | N | R | 0.0862 | |
| 256 | E | R | -1.9406 | |
| 257 | K | R | -2.1896 | |
| 258 | C | R | 0.0000 | |
| 259 | W | R | 0.0000 | |
| 260 | F | R | 0.0000 | |
| 261 | G | R | 0.0000 | |
| 262 | K | R | -2.1847 | |
| 263 | R | R | -2.0227 | |
| 264 | P | R | -1.4519 | |
| 265 | G | R | -0.5396 | |
| 266 | V | R | 0.5036 | |
| 267 | Y | R | 1.3025 | |
| 268 | T | R | 1.0193 | |
| 269 | D | R | 0.7360 | |
| 270 | Y | R | 1.7755 | |
| 271 | I | R | 1.5484 | |
| 272 | Y | R | 0.0000 | |
| 273 | Q | R | 0.0000 | |
| 274 | G | R | 1.0005 | |
| 275 | P | R | 1.0538 | |
| 276 | M | R | 0.0000 | |
| 277 | I | R | 1.5459 | |
| 278 | L | R | 2.3230 | |
| 279 | V | R | 0.0000 | |
| 280 | L | R | 0.0000 | |
| 281 | L | R | 2.8676 | |
| 282 | I | R | 2.8264 | |
| 283 | N | R | 0.0000 | |
| 284 | F | R | 3.5872 | |
| 285 | I | R | 3.5877 | |
| 286 | F | R | 2.3808 | |
| 287 | L | R | 0.0000 | |
| 288 | F | R | 2.6845 | |
| 289 | N | R | 1.2365 | |
| 290 | I | R | 0.0000 | |
| 291 | V | R | 0.4557 | |
| 292 | R | R | -0.5678 | |
| 293 | I | R | 0.1814 | |
| 294 | L | R | 0.0000 | |
| 295 | M | R | -0.3565 | |
| 296 | T | R | -0.6758 | |
| 297 | K | R | 0.0000 | |
| 298 | L | R | 0.0000 | |
| 299 | R | R | -2.1443 | |
| 300 | A | R | -0.8706 | |
| 301 | S | R | -0.6289 | |
| 302 | T | R | -0.8869 | |
| 303 | T | R | -0.9019 | |
| 304 | S | R | -0.9683 | |
| 305 | E | R | -1.9882 | |
| 306 | T | R | -0.7621 | |
| 307 | I | R | -0.1248 | |
| 308 | Q | R | 0.0000 | |
| 309 | Y | R | 0.0483 | |
| 310 | R | R | -1.4839 | |
| 311 | K | R | -0.6176 | |
| 312 | A | R | 0.0000 | |
| 313 | V | R | 0.8815 | |
| 314 | K | R | -0.8296 | |
| 315 | A | R | 0.0000 | |
| 316 | T | R | 1.1123 | |
| 317 | L | R | 1.5232 | |
| 318 | V | R | 0.9811 | |
| 319 | L | R | 0.0000 | |
| 320 | L | R | 1.1327 | |
| 321 | P | R | 0.6492 | |
| 322 | L | R | 0.0000 | |
| 323 | L | R | 0.0000 | |
| 324 | G | R | 0.0000 | |
| 325 | I | R | 0.0000 | |
| 326 | T | R | 0.0000 | |
| 327 | Y | R | 0.0000 | |
| 328 | M | R | 1.5288 | |
| 329 | L | R | 1.6617 | |
| 330 | F | R | 1.8088 | |
| 331 | F | R | 1.4843 | |
| 332 | V | R | 1.3761 | |
| 333 | N | R | 0.0000 | |
| 334 | P | R | -0.8306 | |
| 335 | G | R | -2.0224 | |
| 336 | E | R | -2.8481 | |
| 337 | D | R | -2.6235 | |
| 338 | E | R | -1.9857 | |
| 339 | V | R | 0.4241 | |
| 340 | S | R | -0.1554 | |
| 341 | R | R | -0.5315 | |
| 342 | V | R | 0.9130 | |
| 343 | V | R | 1.7993 | |
| 344 | F | R | 0.0000 | |
| 345 | I | R | 0.0000 | |
| 346 | Y | R | 1.6215 | |
| 347 | F | R | 1.9666 | |
| 348 | N | R | 0.0000 | |
| 349 | S | R | 0.0000 | |
| 350 | F | R | 1.9284 | |
| 351 | L | R | 1.3449 | |
| 352 | E | R | 0.0000 | |
| 353 | S | R | 0.0000 | |
| 354 | F | R | 0.0000 | |
| 355 | Q | R | 0.0000 | |
| 356 | G | R | 0.0000 | |
| 357 | F | R | 1.4938 | |
| 358 | F | R | 1.1203 | |
| 359 | V | R | 0.0000 | |
| 360 | S | R | 0.0000 | |
| 361 | V | R | 1.2052 | |
| 362 | F | R | 1.0372 | |
| 363 | Y | R | 0.0000 | |
| 364 | C | R | 0.0000 | |
| 365 | F | R | 0.7083 | |
| 366 | L | R | 0.6776 | |
| 367 | N | R | 0.0000 | |
| 368 | S | R | -1.3301 | |
| 369 | E | R | -2.3288 | |
| 370 | V | R | 0.0000 | |
| 371 | R | R | -1.7611 | |
| 372 | S | R | -1.7720 | |
| 373 | A | R | -1.8396 | |
| 374 | I | R | -1.8121 | |
| 375 | R | R | -2.3538 | |
| 376 | K | R | -2.3726 | |
| 377 | R | R | -2.0793 | |
| 378 | W | R | -0.7130 | |
| 379 | H | R | -1.5242 | |
| 380 | R | R | -1.1675 | |
| 381 | W | R | 0.2449 | |
| 2 | E | P | -2.1990 | |
| 3 | E | P | -1.9423 | |
| 4 | P | P | -0.9609 | |
| 5 | P | P | -0.1502 | |
| 6 | I | P | 0.7418 | |
| 7 | S | P | 0.0000 | |
| 8 | L | P | 0.0000 | |
| 9 | D | P | -0.1161 | |
| 10 | L | P | 0.0000 | |
| 11 | T | P | 0.0000 | |
| 12 | F | P | 0.0000 | |
| 13 | H | P | 0.0000 | |
| 14 | L | P | 0.0000 | |
| 15 | L | P | 0.0000 | |
| 16 | R | P | -1.1786 | |
| 17 | E | P | -1.3775 | |
| 18 | V | P | -1.1974 | |
| 19 | L | P | 0.0000 | |
| 20 | E | P | -2.3007 | |
| 21 | M | P | 0.0000 | |
| 22 | A | P | -1.3551 | |
| 23 | R | P | -1.6729 | |
| 24 | A | P | -1.4212 | |
| 25 | E | P | -2.4767 | |
| 26 | Q | P | -1.9429 | |
| 27 | L | P | -0.6704 | |
| 28 | A | P | -1.5343 | |
| 29 | Q | P | -2.3016 | |
| 30 | Q | P | -1.9806 | |
| 31 | A | P | -1.6766 | |
| 32 | H | P | -1.8801 | |
| 33 | S | P | -1.6026 | |
| 34 | N | P | -1.8186 |
Calculations for various pH values
This page contains details and comparisons for all models calculated at different pH points.
Please find suggestions on interpreting the results below. More details can be found in the Tutorial.
The input structure is globular. Max score is recommended for pH analysis.
pH |
Average A4D Score |
Max A4D Score |
|||
| 4.0 | -0.4668 | 6.4971 | View | CSV | PDB |
| 4.5 | -0.5178 | 6.4971 | View | CSV | PDB |
| 5.0 | -0.5795 | 6.4971 | View | CSV | PDB |
| 5.5 | -0.641 | 6.4971 | View | CSV | PDB |
| 6.0 | -0.6908 | 6.4971 | View | CSV | PDB |
| 6.5 | -0.7217 | 6.4971 | View | CSV | PDB |
| 7.0 | -0.7337 | 6.4971 | View | CSV | PDB |
| 7.5 | -0.7324 | 6.4971 | View | CSV | PDB |
| 8.0 | -0.7227 | 6.4971 | View | CSV | PDB |
| 8.5 | -0.7061 | 6.4971 | View | CSV | PDB |
| 9.0 | -0.6826 | 6.4971 | View | CSV | PDB |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine