Project name: Q162L

Status: done

Started: 2026-08-16 07:19:50
Chain sequence(s) A: QCIQPGTGYNNGYFYSYWNDGHGGVTYCNGPGGQFSVNWSNSGNFVGGKGWQPGTKNKVINFSGSYNPNGNSYLSVYGWSRNPLIEYYIVENFGTYNPSTGATKLGEVTSDGSVYDIYRTQRVNQPSIIGTATFYQYWSVRRNHRSSGSVNTANHFNAWAQLGLTLGTMDYQIVAVEGYFSSGSASITVS
input PDB
Selected Chain(s) A
Distance of aggregation 10 Å
FoldX usage Yes
pH calculations No
alphaCutter usage No
Dynamic mode No
Automated mutations No
Downloads Download all the data
Simulation log 
[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:02)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:02)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:02)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:02)
[INFO]       FoldX:    Starting FoldX energy minimization                                          (00:00:02)
[INFO]       Analysis: Starting Aggrescan4D on folded.pdb                                          (00:01:54)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:56)
Show buried residues
Minimal score value
-2.501
Maximal score value
1.9588
Average score
-0.4623
Total score value
-87.8364
Download the table (csv)

The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan4D score mutation
1 Q A -0.7995
2 C A 0.1262
3 I A -0.1894
4 Q A -0.8807
5 P A -0.6982
6 G A -0.4351
7 T A 0.0182
8 G A 0.4147
9 Y A 0.7753
10 N A -0.6237
11 N A -1.4691
12 G A -0.7786
13 Y A -0.2297
14 F A 0.0000
15 Y A 0.2300
16 S A 0.0000
17 Y A 0.0000
18 W A -0.0626
19 N A -0.8413
20 D A -1.2790
21 G A -1.4508
22 H A -1.6355
23 G A -1.4373
24 G A -1.1925
25 V A -1.0551
26 T A -0.4634
27 Y A 0.0000
28 C A -0.2373
29 N A 0.0000
30 G A -0.8309
31 P A -1.0679
32 G A -1.0804
33 G A 0.0000
34 Q A -0.8402
35 F A 0.0000
36 S A -0.5258
37 V A 0.0000
38 N A -1.5387
39 W A 0.0000
40 S A -1.1684
41 N A -1.1091
42 S A 0.0000
43 G A 0.0000
44 N A 0.0816
45 F A 0.0000
46 V A 0.0000
47 G A 0.0000
48 G A 0.0000
49 K A 0.0000
50 G A 0.0000
51 W A 0.0948
52 Q A -0.2644
53 P A -0.4608
54 G A 0.0000
55 T A -1.0459
56 K A -1.8859
57 N A -2.0408
58 K A -1.1165
59 V A -0.0194
60 I A 0.0000
61 N A -1.0257
62 F A 0.0000
63 S A -0.7814
64 G A -0.6078
65 S A -0.7444
66 Y A -0.9189
67 N A -1.7735
68 P A -1.5930
69 N A -1.7487
70 G A -0.5517
71 N A 0.2443
72 S A 0.0000
73 Y A 0.0861
74 L A 0.0000
75 S A 0.0000
76 V A 0.0000
77 Y A 0.0000
78 G A 0.0000
79 W A 0.0000
80 S A 0.0000
81 R A -0.9757
82 N A -1.6454
83 P A -1.0086
84 L A -0.1777
85 I A 0.0000
86 E A 0.0000
87 Y A 0.0000
88 Y A 0.0000
89 I A 0.0000
90 V A 0.0000
91 E A 0.0000
92 N A -0.8757
93 F A -0.3090
94 G A -0.6235
95 T A -0.2035
96 Y A 0.4997
97 N A -0.2078
98 P A -0.1236
99 S A 0.0000
100 T A -0.4757
101 G A -0.8407
102 A A -0.9374
103 T A -1.1098
104 K A -1.8799
105 L A -0.6852
106 G A -1.1512
107 E A -1.8075
108 V A -0.9068
109 T A -0.5329
110 S A 0.0000
111 D A -0.9559
112 G A -0.8989
113 S A 0.0000
114 V A -0.9215
115 Y A 0.0000
116 D A -1.3584
117 I A 0.0000
118 Y A -1.0940
119 R A -1.0706
120 T A -0.9631
121 Q A -1.0820
122 R A -0.8997
123 V A 0.3102
124 N A -1.1262
125 Q A -1.1713
126 P A -0.4027
127 S A 0.2346
128 I A 1.2170
129 I A 1.9588
130 G A 0.4147
131 T A -0.2531
132 A A -0.1087
133 T A -0.3360
134 F A 0.0000
135 Y A -0.1132
136 Q A 0.0000
137 Y A 0.0000
138 W A 0.0000
139 S A 0.0000
140 V A 0.0000
141 R A 0.0000
142 R A -2.4898
143 N A -2.5010
144 H A -1.9163
145 R A -1.2602
146 S A -0.7132
147 S A -0.7466
148 G A -0.7951
149 S A -0.6187
150 V A 0.0000
151 N A -0.8165
152 T A 0.0000
153 A A 0.0000
154 N A -1.3713
155 H A 0.0000
156 F A 0.0000
157 N A -1.9466
158 A A -1.3468
159 W A 0.0000
160 A A -0.9296
161 Q A -1.3577
162 L A -0.4047
163 G A -0.5882
164 L A 0.0000
165 T A -0.5189
166 L A -0.5620
167 G A -0.8465
168 T A -0.7761
169 M A 0.0000
170 D A 0.0000
171 Y A 0.0000
172 Q A 0.0000
173 I A 0.0000
174 V A 0.0000
175 A A 0.0000
176 V A 0.0000
177 E A 0.0986
178 G A 0.0000
179 Y A 1.7046
180 F A 1.6663
181 S A 0.0000
182 S A -1.0241
183 G A -1.5918
184 S A -1.3080
185 A A 0.0000
186 S A -0.6804
187 I A 0.0000
188 T A -0.6859
189 V A 0.0000
190 S A -0.4842
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