Project name: eece343a6c843b0

Status: done

Started: 2026-01-03 08:02:59
Chain sequence(s) A: KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
input PDB
Selected Chain(s) A
Distance of aggregation 10 Å
FoldX usage No
pH calculations No
alphaCutter usage No
Dynamic mode No
Automated mutations No
Downloads Download all the data
Simulation log 
[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:01)
[INFO]       Analysis: Starting Aggrescan4D on folded.pdb                                          (00:00:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:02)
Show buried residues
Minimal score value
-4.094
Maximal score value
1.6994
Average score
-0.9227
Total score value
-119.9537
Download the table (csv)

The table below lists A4D score for protein residues. Residues with A4D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan4D score mutation
1 K A -1.0800
2 V A 0.2893
3 F A 0.0000
4 E A -2.0476
5 R A -1.9454
6 C A -1.4548
7 E A -1.8693
8 L A 0.0000
9 A A 0.0000
10 R A -2.1103
11 T A -1.6132
12 L A 0.0000
13 K A -2.6111
14 R A -2.6482
15 L A -1.3840
16 G A -1.5592
17 M A 0.0000
18 D A -2.4595
19 G A -1.8977
20 Y A -1.7502
21 R A -2.6087
22 G A -1.6933
23 I A 0.0000
24 S A -1.4122
25 L A 0.0000
26 A A 0.0000
27 N A -1.1832
28 W A 0.0000
29 M A 0.0000
30 C A 0.0000
31 L A 0.0000
32 A A 0.0000
33 K A -0.8850
34 W A -0.3843
35 E A -0.3446
36 S A -0.7087
37 G A -0.5889
38 Y A 0.0000
39 N A -0.9192
40 T A 0.0000
41 R A -2.0363
42 A A -1.2269
43 T A -0.9915
44 N A -0.8760
45 Y A -0.2293
46 N A -1.2826
47 A A -1.2183
48 G A -1.6108
49 D A -2.5654
50 R A -2.9017
51 S A 0.0000
52 T A 0.0000
53 D A -0.6068
54 Y A 0.0000
55 G A 0.0000
56 I A 0.0000
57 F A 0.0000
58 Q A 0.0000
59 I A 0.0000
60 N A -0.2410
61 S A 0.0000
62 R A -0.2894
63 Y A 1.5692
64 W A 0.5306
65 C A 0.0000
66 N A -1.1807
67 D A -1.6492
68 G A -1.7888
69 K A -2.6031
70 T A 0.0000
71 P A -1.3997
72 G A -0.5816
73 A A 0.2391
74 V A 1.6994
75 N A 0.3311
76 A A 0.3676
77 C A -0.2563
78 H A -0.8342
79 L A -0.7293
80 S A -0.8405
81 C A 0.0000
82 S A -0.6276
83 A A -0.7297
84 L A 0.0000
85 L A -1.3612
86 Q A -2.1083
87 D A -2.3897
88 N A -2.2387
89 I A 0.0000
90 A A -0.8111
91 D A -0.9102
92 A A 0.0000
93 V A 0.0000
94 A A -0.3379
95 C A 0.0000
96 A A 0.0000
97 K A -1.2804
98 R A -1.2068
99 V A 0.0000
100 V A 0.0000
101 R A -2.6314
102 D A -1.9544
103 P A -1.5573
104 Q A -1.8833
105 G A -1.9865
106 I A 0.0000
107 R A -1.2907
108 A A -0.5283
109 W A 0.0000
110 V A 0.6844
111 A A -0.3720
112 W A 0.0000
113 R A -1.9499
114 N A -2.2384
115 R A -2.3187
116 C A 0.0000
117 Q A -2.6571
118 N A -3.1434
119 R A -4.0940
120 D A -3.7435
121 V A -3.0100
122 R A -3.3884
123 Q A -2.7946
124 Y A 0.0000
125 V A -1.3876
126 Q A -2.1030
127 G A -1.1322
128 C A 0.0000
129 G A -0.3981
130 V A -0.0020
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