CABS-flex: server for fast simulation of protein structure fluctuations

This Gallery shows example molecular visualizations of protein structure fluctuations resulted from the CABS-flex server.

Example movies - the CABS-flex automatically generates movies like these for each job run (click to start):

Protein PDB code: 1K40
Protein PDB code: 1HUI
Protein PDB code: 1ASS
Protein PDB code: 1MHN

Visualization of stromal cell-derived factor-1 (1SDF) fluctuations (superimposed models from the CABS-flex server), created using PyMOL.

all-atom representation

Cα trace representation

cartoon representation

Visualization of bovine angiogenin (1AGI) fluctuations (superimposed models from the CABS-flex server), created using PyMOL (colored according to type of secondary structure: beta in red, alpha in cyan, and loops in magenta).

Cα trace representation

cartoon representation

Visualization of FAT domain of focal adhesion kinase (1K40) fluctuations (superimposed models from the CABS-flex server), created using PyMOL (colored according to type of secondary structure: alpha in cyan, and loops in magenta). Additionally, 962ARG side chain was shown (which is one of the residues constituting the interaction site of 1K40).

cartoon representation	Cα trace representation	all-atom representation for the main chain only and 962Arg side chain