CABS-flex
Server for fast simulation of protein structure fluctuationsAs a consequence of publishing a CABS-flex 2.0 server this one will no longer supported. We have disabled new job submissions and previous results will be available untill 4th of April 2018 when the server will be shut down.
CABS-flex 2.0 is available HERE and offers new features that include: extension of the method to significantly larger and multimeric proteins, customizable distance restraints and simulation parameters, contact maps and a new enhanced web server interface (see the paper)
Please contact us at biocomp@chem.uw.edu.pl for support.
Our papers describing the CABS-flex server, methodology and its utilization in other modeling pipelines:
CABS-flex: server for fast simulation of protein structure fluctuations, Nucleic Acids Res. 41, W427-W431, 2013
CABS-flex predictions of protein flexibility compared with NMR ensembles, Bioinformatics 30 (15), pp. 2150-2154, 2014
A Consistent View of Protein Fluctuations from All-atom Molecular Dynamics and Coarse-Grained Dynamics with Knowledge-based Force-field, J. Chem. Theory Comput., 9 (1), pp 119–125, 2013
AGGRESCAN3D (A3D): server for prediction of aggregation properties of protein structures, Nucleic Acids Res., 2015 |
© Laboratory of Theory of Biopolymers, Faculty of Chemistry, University of Warsaw 2013